Gene detail

Detailed information of XP_068752186.1 in Montipora capricornis

Genomic Location: chr5:16865492...16870144
NR annotation: XP_029182666.2, EH domain-containing protein 3-like [Acropora millepora]
Species Montipora capricornis · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

rna-XM_068896085.1

CGCAGATGCATGGAAGGAGTCTGTCACACCTATATGAGagcaaatgaaacaaatgaaagaagaattccTCGTGGCTGCCCAGTTATTGTGATTCTTTCAAGTCACTAGCTTTGACCTTAGGCCTCAGCCGATTCTTCAAGATGTTTTCGTGGATGAAAAAGAATGACGCTCAAAGAAACCCTCAAGTTTTCAACTCCGTGGTTGACGGCCTGAGGAAGTTGTATTTCAAGACTTTAAAACCGCTTGAAGAAGCTTACcttttcaatgaatttcattcaCCGGTTATGTCTGATCCTGACTTTGTTGCAAAGCCGATGGTTTTGCTTGTTGGTCAGTATTCTACTGGCAAGACAACGTTCATTCGATATCTGCTGGAGCGAGAATTTCCGGGCTTGCGAATTGGTCCCGAACCGACAACCGATAGCTTCATAGCTGTTATGCATGGCGAGAACGAACAAGTTGTCCCTGGAAATGCCTTGATTGTGGACCCATCGAAGCCTTTTCGCTCCCTCAGTTCATTTGGCAATGCGTTTCTCAACAGATTTTGCTGTTCCGAGCTTCCAAGCCCTGTCCTTGAGAGCATATCAATTGTCGACACACCTGGGATATTATCAGGAGAAAAGCAAAGTGTCGCTAGAGGATATGATTTCACTGGCATTCTCAAATGGTTTGCTGAACGCTGCGATCGAATAATTCTGCTATTCGATGCACACAAACTGGACATTTCTGACGAGTTTCAGCGTGGGATCGAAGTGCTTCGCGACTATGATGATAAAATCAGGATCGTTCTCAACAAGGCCGATATGGTGACGACTCAACAGCTGATGCGAGTCTATGGAGCTTTGATGTGGTCCTTAGGGAAAGTCATAAATACACCTGAAGTTGCCCGTGTCTATATTGGTTCTTTTTGGGACCAGCCgcttcaaaatgatgaaaatcgAAAGCTTTTTGAGTATGAAGCTAACGATCTTTTCACTGATATCCAAACCTTGCCTAGGAATGCTGCCTTACGAAAGTtaaatgattttattaaaagAGCTCGATTAGCAAAGGTCCATGCTTACGTCATTGCTGAACTGAAAAACCAAATGCCAGCAGTGTTTGGCAAAGAGAAAAAGAAGGAGCAACTTCTTAAAAACCTCTCTGAGGTGTACATGAAGATACAAAAAGAGCAGAATATCTCTCCAGGTGACTTTCCCTCTGTGGTGAAATTTAAGGAGCAACTGCGTAAGTATGATTTCTCCAAGTTCCATCCCATAAGAACAAAGTTGATTGAATCACTTGACCGTATGCTGGCTAACGATATTCCACGTCTAATGGGGATGATTCCTTTGGAGGCGGATTCTAATTATGGGCAACAGGCTGCTGTGAAGGGAGGAGCGTTTACTGTCAGCCATTCTACCAATAATCCATTTGCCTCTGGTGCCTGCCAAGGCCTGGCTTTAGGTTCCGAGACAGATGCTTGGGTTGTGGAAGAATTCAAAGATGAGTATGACAGGTTATTCAAGAGCCTTGGCCCCAAGAATGGAAAGATCAGTGGTGCAgtggcaaagaaagaaatggtcAAGTCAAAACTGCAGAACACAGTGTTAGGAAAGATATGGACACTGTCAGACATTGATCGGGATGGGCAGTTAGACGAAGAGGAGTTTGCACTGGCTATGTACTTGATTAAAGTCAAGTTGAATGAAGATGATGACTTACCCGATGAACTTCCCACACATCTGATTCCACCATCAAAGCGTGTTACCAATGGGATCGATGACTAAAATACTGCAACAATTTAAATCTGCATAAAAGCTACTTAAACAATCACCAGGGGTGAAGTTAAATAGTTACTTCCAGGGACACCAATAGATTTGCCAACAGGGTCGGTACAGTGCTGTGTGTTTAACTGACTCGTCAGGGTTAAATAACGCAAAAAGGATATTGCACAACTGGCATATTGGCCAACACACCTGTAACTGCAAGTTTAAAGCTCTAGTTGAAGAACTACTGAAATAATTAGGCATATATTGTTGGAAGTGACATCCAAATTCAAAATTCATTCCGGCAAGAGAGTTGTTGGGTTAAAGCTGCTGTAATAAATTTTGTCTTTTTAGGGTGGTTTTGTCATGGAGACACATGTATAATGGCAAAATGGTAAATTAAACAGCAAGTGAGAGTGAGCCCTGTTGATTGATGTATCAGCAAAGGAATTGAAGAAATTTGACCCTGGGTATGTGTAGTGAAACCCTGGTTAAATTATACATCAAGTGCTCTTTACAAGAATACCTGCTCCCTGTAAGGAAggtataataataaattatttattattattggttatGTCTGTTAGCTTTAAAAGAAATCATGGTGGTGTTTGATGGGGTTTCACTATGTCTTGCCTATGATTTTCCACAAAATGCTGATTCGTGATAACGCCTGACATAAACAGTGGCTATTCTTGTTTTATCTTATTTAAGTTTCCTTAGTTGTAGCGTAGCAATAATATTACcaaattattttgttgtaaCAGAAAGATAACCTTTAGAAGGTGTGATATTTTTTATTTGGGTAAGTGATCGCCttagaacaaaattaatgattaataATTAAGTGTACAAGGGAGACATCTTTAATATTATATTTCACGTGGTATTGAAGGAGCCTATAGTTGTCCTTTCCACCTTAAACAGGtgggacctagatgttgttaaccatTTCATGCCCAAGGGGGGCCCCATTGACGGGTAAGATCAGGCGGCGTTAGACAGAATGAACTCTACAAGTGTCACAGAGAATTACAGTGCATTTAATGGTTAATTTGCTATATAGGAGAACAAAAGCACAAAACAAGTTTACAGATATTTTTGATCTACAGCTTTTACCTTAAGTTTCTGTAAGAAAGCAAAGTCCCATTAATTTTGTAAGTGGCCTTTAATTGGGTTTGTAAGAAGGGTAATTTTCAAGGCAAAACTTTTTGCATGGAATAGAAGAATATGTAGAGTGTTACAACCAGGTTTATTTTGCTATCGTAAAATAACTTATTGTATTTTATGCCATTTTGATCCATCACTAGTAAGTTTCCAAGGTTAGGTACAAAAGTTAATAAACTCCTTTGTGACCATAAA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q9H4M9	EH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=EHD1 PE=1 SV=2
Q5RBP4	EH domain-containing protein 1 OS=Pongo abelii OX=9601 GN=EHD1 PE=2 SV=1
Q5E9R3	EH domain-containing protein 1 OS=Bos taurus OX=9913 GN=EHD1 PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0007257 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF18150 all species →	DUF5600	Domain of unknown function (DUF5600)	Domain	Interproscan
PF16880 all species →	EHD_N	N-terminal EH-domain containing protein	Family	Interproscan
PF12763 all species →	EF-hand_4	Cytoskeletal-regulatory complex EF hand	Family	Interproscan
PF00350 all species →	Dynamin_N	Dynamin family	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR002048 all species →	Domain	EF-hand domain	Interproscan
IPR040990 all species →	Domain	Domain of unknown function DUF5600	Interproscan
IPR031692 all species →	Domain	EH domain-containing protein, N-terminal	Interproscan
IPR030381 all species →	Domain	Dynamin-type guanine nucleotide-binding (G) domain	Interproscan
IPR018247 all species →	Binding_site	EF-Hand 1, calcium-binding site	Interproscan
IPR027417 all species →	Homologous_superfamily	P-loop containing nucleoside triphosphate hydrolase	Interproscan
IPR000261 all species →	Domain	EH domain	Interproscan
IPR045063 all species →	Domain	Dynamin, N-terminal	Interproscan
IPR011992 all species →	Homologous_superfamily	EF-hand domain pair	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR11216 all species →	EH DOMAIN	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005509 all species →	Molecular Function	calcium ion binding	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0005886 all species →	Cellular Component	plasma membrane	Interproscan
GO:0006897 all species →	Biological Process	endocytosis	Interproscan
GO:0016197 all species →	Biological Process	endosomal transport	Interproscan
GO:0005525 all species →	Molecular Function	GTP binding	Interproscan
GO:0005515 all species →	Molecular Function	protein binding	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

No KEGG orthology assignment for XP_068752186.1.

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of XP_068752186.1 across 36 RNA-seq samples of Montipora capricornis. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

36Samples

30TPM > 0

1Conditions

90.5Max TPM

40.1Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM	Mean, relative to max
Polyps	36	30	40.10	90.48

Per sample · hover a bar for the full sample record

Show the sample table (36 samples)

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR27940191	Polyps	Polyps	not recorded	not recorded	SRP199550	90.48
SRR12904783	Polyps	Polyps	not recorded	not recorded	SRP199550	90.18
SRR12904782	Polyps	Polyps	not recorded	not recorded	SRP199550	72.13
SRR12904781	Polyps	Polyps	not recorded	not recorded	SRP199550	70.03
SRR27940193	Polyps	Polyps	not recorded	not recorded	SRP199550	68.59
SRR12959227	Polyps	Polyps	E3 day3	not recorded	SRP199550	65.42
SRR12959202	Polyps	Polyps	E3 day15	not recorded	SRP199550	63.39
SRR12959203	Polyps	Polyps	E3 day15	not recorded	SRP199550	63.05
SRR12959201	Polyps	Polyps	E3 day15	not recorded	SRP199550	60.60
SRR12959182	Polyps	Polyps	E3 day0	not recorded	SRP199550	56.62
SRR12959216	Polyps	Polyps	E3 day9	not recorded	SRP199550	54.89
SRR12959215	Polyps	Polyps	E3 day9	not recorded	SRP199550	53.94
SRR12959184	Polyps	Polyps	E3 day0	not recorded	SRP199550	53.84
SRR12959183	Polyps	Polyps	E3 day0	not recorded	SRP199550	53.35
SRR12959214	Polyps	Polyps	E3 day9	not recorded	SRP199550	51.59
SRR12959189	Polyps	Polyps	E3 day21	not recorded	SRP199550	50.80
SRR27940192	Polyps	Polyps	not recorded	not recorded	SRP199550	50.33
SRR12959190	Polyps	Polyps	E3 day21	not recorded	SRP199550	49.65
SRR12959188	Polyps	Polyps	E3 day21	not recorded	SRP199550	49.54
SRR12959229	Polyps	Polyps	E3 day3	not recorded	SRP199550	44.77
SRR12959230	Polyps	Polyps	E3 day3	not recorded	SRP199550	43.87
SRR12786896	Polyps	Polyps	OA3 day0	not recorded	SRP199550	32.38
SRR12786898	Polyps	Polyps	OA3 day0	not recorded	SRP199550	32.24
SRR12786897	Polyps	Polyps	OA3 day0	not recorded	SRP199550	31.31
SRR12710857	Polyps	Polyps	OA3 day9	not recorded	SRP199550	18.25
SRR12710858	Polyps	Polyps	OA3 day9	not recorded	SRP199550	16.38
SRR12710855	Polyps	Polyps	OA3 day9	not recorded	SRP199550	16.25
SRR12710846	Polyps	Polyps	OA3 day3	not recorded	SRP199550	14.13
SRR12710847	Polyps	Polyps	OA3 day3	not recorded	SRP199550	13.47
SRR12710848	Polyps	Polyps	OA3 day3	not recorded	SRP199550	12.28
SRR12807381	Polyps	Polyps	OA3 day0	not recorded	SRP199550	0.00
SRR12849113	Polyps	Polyps	OA3 day0	not recorded	SRP199550	0.00
SRR12927880	Polyps	Polyps	E3 day0	not recorded	SRP199550	0.00
SRR12963484	Polyps	Polyps	E3 day0	not recorded	SRP199550	0.00
SRR9129316	Polyps	Polyps	not recorded	not recorded	SRP199550	0.00
SRR9613519	Polyps	Polyps	not recorded	not recorded	SRP199550	0.00

Source: CnidoSite RNA-seq expression matrices (MCAPR_TPM, StringTie quantification over 36 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Montipora capricornis tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

Direction	Partners	Most correlated partner	PCC
Positively correlated	21	XP_068732601.1	0.95199321290263
Negatively correlated	7	XP_068724527.1	-0.453292205629828

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Montipora capricornis, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	ready	open →
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →