Genomic Location: chr5:21462027...21515770
NR annotation: XP_044183798.1, LOW QUALITY PROTEIN: 1-phosphatidylinositol 3-phosphate 5-kinase-like [Acropora millepora]
Species Montipora capricornis · all data for this species · gene families
| CDS |
| LOC138049905 |
| Transcript |
| rna-XM_068896376.1 |
| Protein |
| XP_068752477.1 |
| UniProt accession | Description |
|---|---|
| Q9Z1T6 | 1-phosphatidylinositol 3-phosphate 5-kinase OS=Mus musculus OX=10090 GN=Pikfyve PE=1 SV=3 |
| Q9Y2I7 | 1-phosphatidylinositol 3-phosphate 5-kinase OS=Homo sapiens OX=9606 GN=PIKFYVE PE=1 SV=3 |
| O96838 | Putative 1-phosphatidylinositol 3-phosphate 5-kinase OS=Drosophila melanogaster OX=7227 GN=fab1 PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0002136 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF01504 all species → | PIP5K | Phosphatidylinositol-4-phosphate 5-Kinase | Family | Interproscan |
| PF00118 all species → | Cpn60_TCP1 | TCP-1/cpn60 chaperonin family | Family | Interproscan |
| PF00610 all species → | DEP | Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) | Domain | Interproscan |
| PF01363 all species → | FYVE | FYVE zinc finger | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR011011 all species → | Homologous_superfamily | Zinc finger, FYVE/PHD-type | Interproscan |
| IPR027483 all species → | Homologous_superfamily | Phosphatidylinositol-4-phosphate 4/5-kinase, C-terminal domain superfamily | Interproscan |
| IPR002498 all species → | Domain | Phosphatidylinositol-4-phosphate 4/5-kinase, core | Interproscan |
| IPR044769 all species → | Domain | 1-phosphatidylinositol-3-phosphate 5-kinase, PIPK catalytic domain | Interproscan |
| IPR027484 all species → | Homologous_superfamily | Phosphatidylinositol-4-phosphate 5-kinase, N-terminal | Interproscan |
| IPR027409 all species → | Homologous_superfamily | GroEL-like apical domain superfamily | Interproscan |
| IPR000306 all species → | Domain | FYVE zinc finger | Interproscan |
| IPR043548 all species → | Family | 1-phosphatidylinositol-3phosphate-5-kinase | Interproscan |
| IPR002423 all species → | Family | Chaperonin Cpn60/GroEL/TCP-1 family | Interproscan |
| IPR036390 all species → | Homologous_superfamily | Winged helix DNA-binding domain superfamily | Interproscan |
| IPR000591 all species → | Domain | DEP domain | Interproscan |
| IPR017455 all species → | Domain | Zinc finger, FYVE-related | Interproscan |
| IPR036388 all species → | Homologous_superfamily | Winged helix-like DNA-binding domain superfamily | Interproscan |
| IPR013083 all species → | Homologous_superfamily | Zinc finger, RING/FYVE/PHD-type | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR46715 all species → | 1-PHOSPHATIDYLINOSITOL 3-PHOSPHATE 5-KINASE | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0046488 all species → | Biological Process | phosphatidylinositol metabolic process | Interproscan |
| GO:0052742 all species → | Molecular Function | phosphatidylinositol kinase activity | Interproscan |
| GO:0000285 all species → | Molecular Function | 1-phosphatidylinositol-3-phosphate 5-kinase activity | Interproscan |
| GO:0046872 all species → | Molecular Function | metal ion binding | Interproscan |
| GO:0012506 all species → | Cellular Component | vesicle membrane | Interproscan |
| GO:0030593 all species → | Biological Process | neutrophil chemotaxis | Interproscan |
| GO:0031410 all species → | Cellular Component | cytoplasmic vesicle | Interproscan |
| GO:0032438 all species → | Biological Process | melanosome organization | Interproscan |
| GO:0052810 all species → | Molecular Function | 1-phosphatidylinositol-5-kinase activity | Interproscan |
| GO:0090385 all species → | Biological Process | phagosome-lysosome fusion | Interproscan |
| GO:1903426 all species → | Biological Process | regulation of reactive oxygen species biosynthetic process | Interproscan |
| GO:0005524 all species → | Molecular Function | ATP binding | Interproscan |
| GO:0035556 all species → | Biological Process | intracellular signal transduction | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K00921 | PIKFYVE, FAB1; 1-phosphatidylinositol-3-phosphate 5-kinase | EC:2.7.1.150 | Membrane trafficking | ko04131 | deepkoala |
Transcript abundance of XP_068752477.1 across 36 RNA-seq samples of Montipora capricornis. This gene has no row in the species' RNA-seq expression matrix, so every value below is shown as zero — the matrix simply does not cover this transcript. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| Polyps | 36 | 0 | 0.00 | 0.00 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| SRR12710846 | Polyps | Polyps | OA3 day3 | not recorded | SRP199550 | 0.00 |
| SRR12710847 | Polyps | Polyps | OA3 day3 | not recorded | SRP199550 | 0.00 |
| SRR12710848 | Polyps | Polyps | OA3 day3 | not recorded | SRP199550 | 0.00 |
| SRR12710855 | Polyps | Polyps | OA3 day9 | not recorded | SRP199550 | 0.00 |
| SRR12710857 | Polyps | Polyps | OA3 day9 | not recorded | SRP199550 | 0.00 |
| SRR12710858 | Polyps | Polyps | OA3 day9 | not recorded | SRP199550 | 0.00 |
| SRR12786896 | Polyps | Polyps | OA3 day0 | not recorded | SRP199550 | 0.00 |
| SRR12786897 | Polyps | Polyps | OA3 day0 | not recorded | SRP199550 | 0.00 |
| SRR12786898 | Polyps | Polyps | OA3 day0 | not recorded | SRP199550 | 0.00 |
| SRR12807381 | Polyps | Polyps | OA3 day0 | not recorded | SRP199550 | 0.00 |
| SRR12849113 | Polyps | Polyps | OA3 day0 | not recorded | SRP199550 | 0.00 |
| SRR12904781 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR12904782 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR12904783 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR12927880 | Polyps | Polyps | E3 day0 | not recorded | SRP199550 | 0.00 |
| SRR12959182 | Polyps | Polyps | E3 day0 | not recorded | SRP199550 | 0.00 |
| SRR12959183 | Polyps | Polyps | E3 day0 | not recorded | SRP199550 | 0.00 |
| SRR12959184 | Polyps | Polyps | E3 day0 | not recorded | SRP199550 | 0.00 |
| SRR12959188 | Polyps | Polyps | E3 day21 | not recorded | SRP199550 | 0.00 |
| SRR12959189 | Polyps | Polyps | E3 day21 | not recorded | SRP199550 | 0.00 |
| SRR12959190 | Polyps | Polyps | E3 day21 | not recorded | SRP199550 | 0.00 |
| SRR12959201 | Polyps | Polyps | E3 day15 | not recorded | SRP199550 | 0.00 |
| SRR12959202 | Polyps | Polyps | E3 day15 | not recorded | SRP199550 | 0.00 |
| SRR12959203 | Polyps | Polyps | E3 day15 | not recorded | SRP199550 | 0.00 |
| SRR12959214 | Polyps | Polyps | E3 day9 | not recorded | SRP199550 | 0.00 |
| SRR12959215 | Polyps | Polyps | E3 day9 | not recorded | SRP199550 | 0.00 |
| SRR12959216 | Polyps | Polyps | E3 day9 | not recorded | SRP199550 | 0.00 |
| SRR12959227 | Polyps | Polyps | E3 day3 | not recorded | SRP199550 | 0.00 |
| SRR12959229 | Polyps | Polyps | E3 day3 | not recorded | SRP199550 | 0.00 |
| SRR12959230 | Polyps | Polyps | E3 day3 | not recorded | SRP199550 | 0.00 |
| SRR12963484 | Polyps | Polyps | E3 day0 | not recorded | SRP199550 | 0.00 |
| SRR27940191 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR27940192 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR27940193 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR9129316 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR9613519 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
Source: CnidoSite RNA-seq expression matrices (MCAPR_TPM,
StringTie quantification over 36 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
Genes whose expression across the transcriptome samples of Montipora capricornis tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
| Direction | Partners | Most correlated partner | PCC |
|---|---|---|---|
| Positively correlated | 0 | not in this network | - |
| Negatively correlated | 0 | not in this network | - |
This gene has no edge at all in the Montipora capricornis network, in either direction — it is not one of the genes the network was built from (the network covers genes with enough expression variation across the transcriptome samples). The counts above are a property of the network, not a failed lookup.
Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.
Whether this gene can be visualised in the single-cell atlases of Montipora capricornis, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |