Gene detail

Detailed information of XP_068753676.1 in Montipora capricornis

Genomic Location: chr6:7282785...7302835
NR annotation: CAH3016208.1, unnamed protein product [Porites evermanni]
Species Montipora capricornis · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

rna-XM_068897575.1

AAATCACATTGTCGCCTGTCAGAACTTGACTAAGAAAGCATACCAACATGTGGTGCTGAAACATGCAATAGATTGTGAATATTTTTCTCTCGATCTTTTTCGCAACAAAGAACTTCAAAATGTTCTTAGTCCGTTCAGCTTTCTGGAGTCCAGCTCTGAGAATCCTTGGAACAAGAACCATTTTTTTGCCTCCCAATGAACCACCGACAAACCTTGAAAAAAACAGTGTCGACCTGCAGACGTTAAAAACAGAAATAGAAAGGGTGGAGAATGAAACTGTGGAAATTCCCTGCATCATTGGTGGAAAAGAAATTTATACTGGCAATACAAAATATCAATTAGCGCCTTACAACCACTCATTAAGGATTGCCAAGTACCATATGGCTACCGAGGAAGTTGTCATTAAGGCTATTGAAAGTGCAATGGCTGCAAGGAAGGAGTGGGAAAGAACTTCTCATGAACACAGGGCTGCCATTTTCCAGAAAGTAGCCGATTTAATTACTGGAAAATACAGAATTCAATCATTAGCAGCAACCATGGTGGGACAGGCCAAGACTGCATTTGAGGCTGATATCGACTGTGTGCAAGAGATAGCAGACTTTTACAGATTTGGAGTTCACTATGCCAAGGAACTACATGGAGGTCCAGAACTTCACCAGCCTCGTGGTGTAATAAACAGACTTGTGTATAGAGGATTGGAGGGTTTCATCGCTGCCATTTCTCCATTCAATTTCACTGCAATTGGAGGAAACTTGGCAGGGACTCCAGCTATTGTTGGCAATGTCATGCTCTGGAAACCTTCATCCACTGCAATCCTTTCTTGCTACCTGGTGCAAAAGATATTTCATGAAGCTGGTCTTCCAGATGGTGTGGTAAATTTTCTTCCTTCATCTGGGAAGACCTTCGGTGACAGTATAACAAAGTCGCCTCATCTAGCAGGAATCAACTTTACTGGCAGTGTCGAGACTTTCAGATATATTTGGAAGAAAGTTGCAGAGAACCTTGATGTTTACCGAACCTATCCAAGACTTGTTGGAGAATGTGGCGGGAAGAATTATCACTTTATCCACCCGTCTGCAGATGTCGaCACAGCTGTTAACTGCACCATCAGGGCAGCATTTGGTTACGCAGGGCAGAAATGTTCTGCGTGCTCGAGACTGTACGTCCCAGAGTCACTGTGGGGACAGattaaagaaagaGTTGTTGAAGAACAGAAAAGGCTCAAGTTGGGAACGCCTAGTGACTATGATACATTTATTTCGGCAGTTATAGATGAGAAGGCGTACAAGAGTATTAAGAGTTACATTGATTATGCAAAGGACAGCCCTGATCTCAGTATTTTAGCCGGAGGAAACTGTGACTCCAGTGTGGGATATTTCATCGAACCAACGATCATTGAAACAAAGAATCCTCACGACAAACTCATGAATGAGGAAATATTTGGACCGGTGCTTACAGTTTACGTTTACCATGATCTAAAATACAAGGAAGCGCTTGACTTGGTTGATAGGACGTCTCCTTTCGCTTTGACTGGAGCAATTTTCGCTAAAGACAGACGTTTTATTCAAGAAGCTTCTGACATCCTTAGAGACGCTGCGGGTAACTTTTACATCAATGACAAATGTACCGGATCCATTGTGGGACAACAGCCCTTCGGAGGGGCGCGGCTTTCAGgCACAAACGACAAAGCTGGCAGTTCGCATTACATCACGCGATGGGTTTCTCCACAGAGCATCAAGGAAACTGTTGTGCCTATTGAGGACTATAAATATCCTCATCACAGTTGAAACAACACCGTTGCAACGCTATGTTCCAAgataaacaaaaagcaaaccCCTTAGGTTCATACTATACCAATGACGTTGAAGGAATCAAAATATGCATCCCAGTTTTGGGGCTCCTGATTGTATTGGGGGGTGAGGCGCTAACGAGCAAGCGCCGGAgacgctaacttgtaggggaaagggcgggggggggggggggttcaggaggaattctccgccagaaaattttgaaatcttgaagctcggaaatgctactttcagccATCTCGACGAAATATCAAAAAGATAACCTTGGAtcaaccgtaaaatgacagatgtttttcttcttgtttttatttttttcttgaaatttggAAAGGGGGCTAGAAGAAACGTACATTGGTCGTCATTTTACTATATGGTGTGTTGATACAGAAACTGTCGAATTTTATTGAAATATTGTACTTACTATATATAATCTATTCATCCatagttttaattaatataataaAGGGAATTTATTGAAAGTA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q8CHT0	Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial OS=Mus musculus OX=10090 GN=Aldh4a1 PE=1 SV=3
A7YWE4	Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial OS=Bos taurus OX=9913 GN=ALDH4A1 PE=2 SV=1
P30038	Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=ALDH4A1 PE=1 SV=3

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0004619 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00171 all species →	Aldedh	Aldehyde dehydrogenase family	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR050485 all species →	Family	Proline metabolism enzyme	Interproscan
IPR005931 all species →	Family	Delta-1-pyrroline-5-carboxylate dehydrogenase	Interproscan
IPR015590 all species →	Domain	Aldehyde dehydrogenase domain	Interproscan
IPR016162 all species →	Homologous_superfamily	Aldehyde dehydrogenase, N-terminal	Interproscan
IPR016160 all species →	Conserved_site	Aldehyde dehydrogenase, cysteine active site	Interproscan
IPR016163 all species →	Homologous_superfamily	Aldehyde dehydrogenase, C-terminal	Interproscan
IPR016161 all species →	Homologous_superfamily	Aldehyde/histidinol dehydrogenase	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR42862 all species →	DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE 1, ISOFORM A-RELATED	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0003842 all species →	Molecular Function	1-pyrroline-5-carboxylate dehydrogenase activity	Interproscan
GO:0005759 all species →	Cellular Component	mitochondrial matrix	Interproscan
GO:0010133 all species →	Biological Process	proline catabolic process to glutamate	Interproscan
GO:0016491 all species →	Molecular Function	oxidoreductase activity	Interproscan
GO:0016620 all species →	Molecular Function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K00294	E1.2.1.88; 1-pyrroline-5-carboxylate dehydrogenase	EC:1.2.1.88	Arginine and proline metabolism	ko00330	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of XP_068753676.1 across 36 RNA-seq samples of Montipora capricornis. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

36Samples

28TPM > 0

1Conditions

40.0Max TPM

17.0Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM	Mean, relative to max
Polyps	36	28	16.99	40.01

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR12959203	Polyps	Polyps	E3 day15	not recorded	SRP199550	40.01
SRR12959202	Polyps	Polyps	E3 day15	not recorded	SRP199550	39.92
SRR12959201	Polyps	Polyps	E3 day15	not recorded	SRP199550	38.99
SRR12959214	Polyps	Polyps	E3 day9	not recorded	SRP199550	30.42
SRR12959215	Polyps	Polyps	E3 day9	not recorded	SRP199550	29.57
SRR12959216	Polyps	Polyps	E3 day9	not recorded	SRP199550	29.50
SRR12959189	Polyps	Polyps	E3 day21	not recorded	SRP199550	25.67
SRR12959190	Polyps	Polyps	E3 day21	not recorded	SRP199550	23.82
SRR12959188	Polyps	Polyps	E3 day21	not recorded	SRP199550	23.32
SRR27940191	Polyps	Polyps	not recorded	not recorded	SRP199550	23.17
SRR12904783	Polyps	Polyps	not recorded	not recorded	SRP199550	23.14
SRR12786898	Polyps	Polyps	OA3 day0	not recorded	SRP199550	22.66
SRR12786897	Polyps	Polyps	OA3 day0	not recorded	SRP199550	22.01
SRR12904781	Polyps	Polyps	not recorded	not recorded	SRP199550	21.59
SRR27940192	Polyps	Polyps	not recorded	not recorded	SRP199550	20.63
SRR12904782	Polyps	Polyps	not recorded	not recorded	SRP199550	20.55
SRR12786896	Polyps	Polyps	OA3 day0	not recorded	SRP199550	19.22
SRR12959182	Polyps	Polyps	E3 day0	not recorded	SRP199550	18.60
SRR12959183	Polyps	Polyps	E3 day0	not recorded	SRP199550	17.63
SRR27940193	Polyps	Polyps	not recorded	not recorded	SRP199550	17.52
SRR12959184	Polyps	Polyps	E3 day0	not recorded	SRP199550	17.02
SRR12959229	Polyps	Polyps	E3 day3	not recorded	SRP199550	16.24
SRR12710858	Polyps	Polyps	OA3 day9	not recorded	SRP199550	14.32
SRR12710857	Polyps	Polyps	OA3 day9	not recorded	SRP199550	14.30
SRR12710855	Polyps	Polyps	OA3 day9	not recorded	SRP199550	11.29
SRR12710846	Polyps	Polyps	OA3 day3	not recorded	SRP199550	11.13
SRR12710847	Polyps	Polyps	OA3 day3	not recorded	SRP199550	9.74
SRR12710848	Polyps	Polyps	OA3 day3	not recorded	SRP199550	9.64
SRR12807381	Polyps	Polyps	OA3 day0	not recorded	SRP199550	0.00
SRR12849113	Polyps	Polyps	OA3 day0	not recorded	SRP199550	0.00
SRR12927880	Polyps	Polyps	E3 day0	not recorded	SRP199550	0.00
SRR12959227	Polyps	Polyps	E3 day3	not recorded	SRP199550	0.00
SRR12959230	Polyps	Polyps	E3 day3	not recorded	SRP199550	0.00
SRR12963484	Polyps	Polyps	E3 day0	not recorded	SRP199550	0.00
SRR9129316	Polyps	Polyps	not recorded	not recorded	SRP199550	0.00
SRR9613519	Polyps	Polyps	not recorded	not recorded	SRP199550	0.00

Source: CnidoSite RNA-seq expression matrices (MCAPR_TPM, StringTie quantification over 36 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.