Detailed information of XP_068754658.1 in Montipora capricornis

Genomic Location: chr6:41876270...41934503
NR annotation: XP_029187317.2, chromodomain-helicase-DNA-binding protein 4-like isoform X5 [Acropora millepora]
Species Montipora capricornis · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
A2A8L1Chromodomain-helicase-DNA-binding protein 5 OS=Mus musculus OX=10090 GN=Chd5 PE=1 SV=1
Q12873Chromodomain-helicase-DNA-binding protein 3 OS=Homo sapiens OX=9606 GN=CHD3 PE=1 SV=3
D3ZD32Chromodomain-helicase-DNA-binding protein 5 OS=Rattus norvegicus OX=10116 GN=Chd5 PE=1 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0001718 (this species only) · gene tree & orthology
Ubiquitin familyE3|E3 activity RING|PHD · all ubiquitin genes in this species

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF00271
all species →
Helicase_CHelicase conserved C-terminal domainDomainInterproscan
PF00176
all species →
SNF2-rel_domSNF2-related domainDomainInterproscan
PF06461
all species →
CHDII_SANT-likeCHD subfamily II, SANT-like domainDomainInterproscan
PF06465
all species →
DUF1087CHD subfamily II, DUF1087DomainInterproscan
PF08074
all species →
CHDCT2CHDCT2 (NUC038) domainDomainInterproscan
PF00628
all species →
PHDPHD-fingerDomainInterproscan
PF00385
all species →
ChromoChromo (CHRromatin Organisation MOdifier) domainDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR013083
all species →
Homologous_superfamilyZinc finger, RING/FYVE/PHD-typeInterproscan
IPR002464
all species →
Conserved_siteDNA/RNA helicase, ATP-dependent, DEAH-box type, conserved siteInterproscan
IPR027417
all species →
Homologous_superfamilyP-loop containing nucleoside triphosphate hydrolaseInterproscan
IPR016197
all species →
Homologous_superfamilyChromo-like domain superfamilyInterproscan
IPR009463
all species →
DomainDomain of unknown function DUF1087Interproscan
IPR000953
all species →
DomainChromo/chromo shadow domainInterproscan
IPR001650
all species →
DomainHelicase, C-terminal domain-likeInterproscan
IPR011011
all species →
Homologous_superfamilyZinc finger, FYVE/PHD-typeInterproscan
IPR009462
all species →
DomainCHD subfamily II, SANT-like domainInterproscan
IPR001965
all species →
DomainZinc finger, PHD-typeInterproscan
IPR019787
all species →
DomainZinc finger, PHD-fingerInterproscan
IPR000330
all species →
DomainSNF2, N-terminalInterproscan
IPR014001
all species →
DomainHelicase superfamily 1/2, ATP-binding domainInterproscan
IPR038718
all species →
Homologous_superfamilySNF2-like, N-terminal domain superfamilyInterproscan
IPR049730
all species →
DomainSNF2/RAD5-like, C-terminal helicase domainInterproscan
IPR012957
all species →
DomainCHD, C-terminal 2Interproscan
IPR023780
all species →
DomainChromo domainInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR45623
all species →
CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATEDInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0003677
all species →
Molecular FunctionDNA bindingInterproscan
GO:0006338
all species →
Biological Processchromatin remodelingInterproscan
GO:0005524
all species →
Molecular FunctionATP bindingInterproscan
GO:0140658
all species →
Molecular FunctionATP-dependent chromatin remodeler activityInterproscan
GO:0000785
all species →
Cellular ComponentchromatinInterproscan
GO:0003682
all species →
Molecular Functionchromatin bindingInterproscan
GO:0005634
all species →
Cellular ComponentnucleusInterproscan
GO:0016887
all species →
Molecular FunctionATP hydrolysis activityInterproscan
GO:0042393
all species →
Molecular Functionhistone bindingInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K11643CHD4, MI2B; chromodomain-helicase-DNA-binding protein 4EC:5.6.2.-
Chromosome and associated proteinsko03036deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of XP_068754658.1 across 36 RNA-seq samples of Montipora capricornis. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

36Samples
29TPM > 0
1Conditions
30.6Max TPM
9.2Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
Polyps 36 29 9.23 30.59

Per sample · hover a bar for the full sample record

Show the sample table (36 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
SRR12904783 Polyps Polyps not recorded not recorded SRP199550 30.59
SRR27940191 Polyps Polyps not recorded not recorded SRP199550 30.50
SRR12959230 Polyps Polyps E3 day3 not recorded SRP199550 24.87
SRR12959227 Polyps Polyps E3 day3 not recorded SRP199550 21.34
SRR27940193 Polyps Polyps not recorded not recorded SRP199550 16.89
SRR12786898 Polyps Polyps OA3 day0 not recorded SRP199550 16.76
SRR12786897 Polyps Polyps OA3 day0 not recorded SRP199550 16.62
SRR12904781 Polyps Polyps not recorded not recorded SRP199550 15.99
SRR12786896 Polyps Polyps OA3 day0 not recorded SRP199550 15.64
SRR12904782 Polyps Polyps not recorded not recorded SRP199550 14.11
SRR12959184 Polyps Polyps E3 day0 not recorded SRP199550 10.94
SRR12959182 Polyps Polyps E3 day0 not recorded SRP199550 10.65
SRR12959183 Polyps Polyps E3 day0 not recorded SRP199550 10.27
SRR12959203 Polyps Polyps E3 day15 not recorded SRP199550 8.86
SRR12959201 Polyps Polyps E3 day15 not recorded SRP199550 8.76
SRR12959202 Polyps Polyps E3 day15 not recorded SRP199550 8.75
SRR12959214 Polyps Polyps E3 day9 not recorded SRP199550 7.86
SRR12959216 Polyps Polyps E3 day9 not recorded SRP199550 7.64
SRR12959215 Polyps Polyps E3 day9 not recorded SRP199550 7.54
SRR12959229 Polyps Polyps E3 day3 not recorded SRP199550 6.96
SRR12959188 Polyps Polyps E3 day21 not recorded SRP199550 5.87
SRR12710847 Polyps Polyps OA3 day3 not recorded SRP199550 5.02
SRR12959190 Polyps Polyps E3 day21 not recorded SRP199550 4.91
SRR12710857 Polyps Polyps OA3 day9 not recorded SRP199550 4.56
SRR12710848 Polyps Polyps OA3 day3 not recorded SRP199550 4.55
SRR12959189 Polyps Polyps E3 day21 not recorded SRP199550 4.20
SRR12710846 Polyps Polyps OA3 day3 not recorded SRP199550 4.12
SRR12710855 Polyps Polyps OA3 day9 not recorded SRP199550 3.99
SRR12710858 Polyps Polyps OA3 day9 not recorded SRP199550 3.60
SRR12807381 Polyps Polyps OA3 day0 not recorded SRP199550 0.00
SRR12849113 Polyps Polyps OA3 day0 not recorded SRP199550 0.00
SRR12927880 Polyps Polyps E3 day0 not recorded SRP199550 0.00
SRR12963484 Polyps Polyps E3 day0 not recorded SRP199550 0.00
SRR27940192 Polyps Polyps not recorded not recorded SRP199550 0.00
SRR9129316 Polyps Polyps not recorded not recorded SRP199550 0.00
SRR9613519 Polyps Polyps not recorded not recorded SRP199550 0.00

Source: CnidoSite RNA-seq expression matrices (MCAPR_TPM, StringTie quantification over 36 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Montipora capricornis tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated42XP_068728388.10.984373905294061
Negatively correlated3XP_068724527.1-0.337096023321159

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Montipora capricornis, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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