Genomic Location: chr6:41876270...41934503
NR annotation: XP_029187317.2, chromodomain-helicase-DNA-binding protein 4-like isoform X5 [Acropora millepora]
Species Montipora capricornis · all data for this species · gene families
| CDS |
| LOC138052178 |
| Transcript |
| rna-XM_068898557.1 |
| Protein |
| XP_068754658.1 |
| UniProt accession | Description |
|---|---|
| A2A8L1 | Chromodomain-helicase-DNA-binding protein 5 OS=Mus musculus OX=10090 GN=Chd5 PE=1 SV=1 |
| Q12873 | Chromodomain-helicase-DNA-binding protein 3 OS=Homo sapiens OX=9606 GN=CHD3 PE=1 SV=3 |
| D3ZD32 | Chromodomain-helicase-DNA-binding protein 5 OS=Rattus norvegicus OX=10116 GN=Chd5 PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0001718 (this species only) · gene tree & orthology |
| Ubiquitin family | E3|E3 activity RING|PHD · all ubiquitin genes in this species |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00271 all species → | Helicase_C | Helicase conserved C-terminal domain | Domain | Interproscan |
| PF00176 all species → | SNF2-rel_dom | SNF2-related domain | Domain | Interproscan |
| PF06461 all species → | CHDII_SANT-like | CHD subfamily II, SANT-like domain | Domain | Interproscan |
| PF06465 all species → | DUF1087 | CHD subfamily II, DUF1087 | Domain | Interproscan |
| PF08074 all species → | CHDCT2 | CHDCT2 (NUC038) domain | Domain | Interproscan |
| PF00628 all species → | PHD | PHD-finger | Domain | Interproscan |
| PF00385 all species → | Chromo | Chromo (CHRromatin Organisation MOdifier) domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR013083 all species → | Homologous_superfamily | Zinc finger, RING/FYVE/PHD-type | Interproscan |
| IPR002464 all species → | Conserved_site | DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site | Interproscan |
| IPR027417 all species → | Homologous_superfamily | P-loop containing nucleoside triphosphate hydrolase | Interproscan |
| IPR016197 all species → | Homologous_superfamily | Chromo-like domain superfamily | Interproscan |
| IPR009463 all species → | Domain | Domain of unknown function DUF1087 | Interproscan |
| IPR000953 all species → | Domain | Chromo/chromo shadow domain | Interproscan |
| IPR001650 all species → | Domain | Helicase, C-terminal domain-like | Interproscan |
| IPR011011 all species → | Homologous_superfamily | Zinc finger, FYVE/PHD-type | Interproscan |
| IPR009462 all species → | Domain | CHD subfamily II, SANT-like domain | Interproscan |
| IPR001965 all species → | Domain | Zinc finger, PHD-type | Interproscan |
| IPR019787 all species → | Domain | Zinc finger, PHD-finger | Interproscan |
| IPR000330 all species → | Domain | SNF2, N-terminal | Interproscan |
| IPR014001 all species → | Domain | Helicase superfamily 1/2, ATP-binding domain | Interproscan |
| IPR038718 all species → | Homologous_superfamily | SNF2-like, N-terminal domain superfamily | Interproscan |
| IPR049730 all species → | Domain | SNF2/RAD5-like, C-terminal helicase domain | Interproscan |
| IPR012957 all species → | Domain | CHD, C-terminal 2 | Interproscan |
| IPR023780 all species → | Domain | Chromo domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR45623 all species → | CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0003677 all species → | Molecular Function | DNA binding | Interproscan |
| GO:0006338 all species → | Biological Process | chromatin remodeling | Interproscan |
| GO:0005524 all species → | Molecular Function | ATP binding | Interproscan |
| GO:0140658 all species → | Molecular Function | ATP-dependent chromatin remodeler activity | Interproscan |
| GO:0000785 all species → | Cellular Component | chromatin | Interproscan |
| GO:0003682 all species → | Molecular Function | chromatin binding | Interproscan |
| GO:0005634 all species → | Cellular Component | nucleus | Interproscan |
| GO:0016887 all species → | Molecular Function | ATP hydrolysis activity | Interproscan |
| GO:0042393 all species → | Molecular Function | histone binding | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K11643 | CHD4, MI2B; chromodomain-helicase-DNA-binding protein 4 | EC:5.6.2.- | Chromosome and associated proteins | ko03036 | deepkoala |
Transcript abundance of XP_068754658.1 across 36 RNA-seq samples of Montipora capricornis. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| Polyps | 36 | 29 | 9.23 | 30.59 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| SRR12904783 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 30.59 |
| SRR27940191 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 30.50 |
| SRR12959230 | Polyps | Polyps | E3 day3 | not recorded | SRP199550 | 24.87 |
| SRR12959227 | Polyps | Polyps | E3 day3 | not recorded | SRP199550 | 21.34 |
| SRR27940193 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 16.89 |
| SRR12786898 | Polyps | Polyps | OA3 day0 | not recorded | SRP199550 | 16.76 |
| SRR12786897 | Polyps | Polyps | OA3 day0 | not recorded | SRP199550 | 16.62 |
| SRR12904781 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 15.99 |
| SRR12786896 | Polyps | Polyps | OA3 day0 | not recorded | SRP199550 | 15.64 |
| SRR12904782 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 14.11 |
| SRR12959184 | Polyps | Polyps | E3 day0 | not recorded | SRP199550 | 10.94 |
| SRR12959182 | Polyps | Polyps | E3 day0 | not recorded | SRP199550 | 10.65 |
| SRR12959183 | Polyps | Polyps | E3 day0 | not recorded | SRP199550 | 10.27 |
| SRR12959203 | Polyps | Polyps | E3 day15 | not recorded | SRP199550 | 8.86 |
| SRR12959201 | Polyps | Polyps | E3 day15 | not recorded | SRP199550 | 8.76 |
| SRR12959202 | Polyps | Polyps | E3 day15 | not recorded | SRP199550 | 8.75 |
| SRR12959214 | Polyps | Polyps | E3 day9 | not recorded | SRP199550 | 7.86 |
| SRR12959216 | Polyps | Polyps | E3 day9 | not recorded | SRP199550 | 7.64 |
| SRR12959215 | Polyps | Polyps | E3 day9 | not recorded | SRP199550 | 7.54 |
| SRR12959229 | Polyps | Polyps | E3 day3 | not recorded | SRP199550 | 6.96 |
| SRR12959188 | Polyps | Polyps | E3 day21 | not recorded | SRP199550 | 5.87 |
| SRR12710847 | Polyps | Polyps | OA3 day3 | not recorded | SRP199550 | 5.02 |
| SRR12959190 | Polyps | Polyps | E3 day21 | not recorded | SRP199550 | 4.91 |
| SRR12710857 | Polyps | Polyps | OA3 day9 | not recorded | SRP199550 | 4.56 |
| SRR12710848 | Polyps | Polyps | OA3 day3 | not recorded | SRP199550 | 4.55 |
| SRR12959189 | Polyps | Polyps | E3 day21 | not recorded | SRP199550 | 4.20 |
| SRR12710846 | Polyps | Polyps | OA3 day3 | not recorded | SRP199550 | 4.12 |
| SRR12710855 | Polyps | Polyps | OA3 day9 | not recorded | SRP199550 | 3.99 |
| SRR12710858 | Polyps | Polyps | OA3 day9 | not recorded | SRP199550 | 3.60 |
| SRR12807381 | Polyps | Polyps | OA3 day0 | not recorded | SRP199550 | 0.00 |
| SRR12849113 | Polyps | Polyps | OA3 day0 | not recorded | SRP199550 | 0.00 |
| SRR12927880 | Polyps | Polyps | E3 day0 | not recorded | SRP199550 | 0.00 |
| SRR12963484 | Polyps | Polyps | E3 day0 | not recorded | SRP199550 | 0.00 |
| SRR27940192 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR9129316 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR9613519 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
Source: CnidoSite RNA-seq expression matrices (MCAPR_TPM,
StringTie quantification over 36 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
Genes whose expression across the transcriptome samples of Montipora capricornis tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
| Direction | Partners | Most correlated partner | PCC |
|---|---|---|---|
| Positively correlated | 42 | XP_068728388.1 | 0.984373905294061 |
| Negatively correlated | 3 | XP_068724527.1 | -0.337096023321159 |
Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.
Whether this gene can be visualised in the single-cell atlases of Montipora capricornis, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | ready | open → |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |