Genomic Location: chr7:40618384...40629145
NR annotation: XP_044182963.1, 28S rRNA (cytosine-C(5))-methyltransferase-like [Acropora millepora]
Species Montipora capricornis · all data for this species · gene families
| CDS |
| LOC138055968 |
| Transcript |
| rna-XM_068901827.1 |
| Protein |
| XP_068757928.1 |
| UniProt accession | Description |
|---|---|
| Q8K4F6 | 28S rRNA (cytosine-C(5))-methyltransferase OS=Mus musculus OX=10090 GN=Nsun5 PE=1 SV=2 |
| Q96P11 | 28S rRNA (cytosine-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NSUN5 PE=1 SV=2 |
| O14039 | 25S rRNA (cytosine-C(5))-methyltransferase rcm1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=rcm1 PE=3 SV=3 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0004853 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF21153 all species → | NSUN5_N | NOL1/NOP2/Sun domain family member 5, N-terminal domain | Domain | Interproscan |
| PF21148 all species → | NSUN5_fdxn-like | NOL1/NOP2/Sun domain family member 5, ferredoxin-like domain | Domain | Interproscan |
| PF01189 all species → | Methyltr_RsmB-F | 16S rRNA methyltransferase RsmB/F | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR048889 all species → | Domain | NSUN5/RCM1, N-terminal domain | Interproscan |
| IPR049561 all species → | Domain | NOL1/NOP2/NSUN 5/7, ferredoxin-like domain | Interproscan |
| IPR023267 all species → | Family | RNA (C5-cytosine) methyltransferase | Interproscan |
| IPR049560 all species → | Domain | SAM-dependent methyltransferase RsmB-F/NOP2-type, catalytic core | Interproscan |
| IPR001678 all species → | Domain | SAM-dependent methyltransferase RsmB-F/NOP2-type domain | Interproscan |
| IPR029063 all species → | Homologous_superfamily | S-adenosyl-L-methionine-dependent methyltransferase superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR22807 all species → | NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0001510 all species → | Biological Process | RNA methylation | Interproscan |
| GO:0008173 all species → | Molecular Function | RNA methyltransferase activity | Interproscan |
| GO:0008168 all species → | Molecular Function | methyltransferase activity | Interproscan |
| GO:0005730 all species → | Cellular Component | nucleolus | Interproscan |
| GO:0070475 all species → | Biological Process | rRNA base methylation | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K15264 | NSUN5, WBSCR20, RCM1; 25S rRNA (cytosine2278-C5)-methyltransferase | EC:2.1.1.311 | Ribosome biogenesis | ko03009 | deepkoala |
Transcript abundance of XP_068757928.1 across 36 RNA-seq samples of Montipora capricornis. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| Polyps | 36 | 27 | 2.74 | 13.75 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| SRR12959229 | Polyps | Polyps | E3 day3 | not recorded | SRP199550 | 13.75 |
| SRR12786897 | Polyps | Polyps | OA3 day0 | not recorded | SRP199550 | 4.85 |
| SRR12786896 | Polyps | Polyps | OA3 day0 | not recorded | SRP199550 | 4.79 |
| SRR12904781 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 4.70 |
| SRR12904782 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 4.60 |
| SRR27940193 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 4.26 |
| SRR12959182 | Polyps | Polyps | E3 day0 | not recorded | SRP199550 | 4.20 |
| SRR12786898 | Polyps | Polyps | OA3 day0 | not recorded | SRP199550 | 4.12 |
| SRR12959184 | Polyps | Polyps | E3 day0 | not recorded | SRP199550 | 3.88 |
| SRR12710857 | Polyps | Polyps | OA3 day9 | not recorded | SRP199550 | 3.70 |
| SRR27940191 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 3.60 |
| SRR12959183 | Polyps | Polyps | E3 day0 | not recorded | SRP199550 | 3.59 |
| SRR12959202 | Polyps | Polyps | E3 day15 | not recorded | SRP199550 | 3.57 |
| SRR12904783 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 3.52 |
| SRR12959203 | Polyps | Polyps | E3 day15 | not recorded | SRP199550 | 3.45 |
| SRR12710846 | Polyps | Polyps | OA3 day3 | not recorded | SRP199550 | 3.40 |
| SRR12959190 | Polyps | Polyps | E3 day21 | not recorded | SRP199550 | 2.94 |
| SRR12959201 | Polyps | Polyps | E3 day15 | not recorded | SRP199550 | 2.65 |
| SRR12959214 | Polyps | Polyps | E3 day9 | not recorded | SRP199550 | 2.51 |
| SRR12959216 | Polyps | Polyps | E3 day9 | not recorded | SRP199550 | 2.47 |
| SRR12710855 | Polyps | Polyps | OA3 day9 | not recorded | SRP199550 | 2.36 |
| SRR12959215 | Polyps | Polyps | E3 day9 | not recorded | SRP199550 | 2.32 |
| SRR12710858 | Polyps | Polyps | OA3 day9 | not recorded | SRP199550 | 2.22 |
| SRR12710847 | Polyps | Polyps | OA3 day3 | not recorded | SRP199550 | 2.19 |
| SRR12710848 | Polyps | Polyps | OA3 day3 | not recorded | SRP199550 | 2.14 |
| SRR12959188 | Polyps | Polyps | E3 day21 | not recorded | SRP199550 | 1.97 |
| SRR12959189 | Polyps | Polyps | E3 day21 | not recorded | SRP199550 | 1.05 |
| SRR12807381 | Polyps | Polyps | OA3 day0 | not recorded | SRP199550 | 0.00 |
| SRR12849113 | Polyps | Polyps | OA3 day0 | not recorded | SRP199550 | 0.00 |
| SRR12927880 | Polyps | Polyps | E3 day0 | not recorded | SRP199550 | 0.00 |
| SRR12959227 | Polyps | Polyps | E3 day3 | not recorded | SRP199550 | 0.00 |
| SRR12959230 | Polyps | Polyps | E3 day3 | not recorded | SRP199550 | 0.00 |
| SRR12963484 | Polyps | Polyps | E3 day0 | not recorded | SRP199550 | 0.00 |
| SRR27940192 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR9129316 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR9613519 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
Source: CnidoSite RNA-seq expression matrices (MCAPR_TPM,
StringTie quantification over 36 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
Genes whose expression across the transcriptome samples of Montipora capricornis tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
| Direction | Partners | Most correlated partner | PCC |
|---|---|---|---|
| Positively correlated | 40 | XP_068720929.1 | 0.94773333648973 |
| Negatively correlated | 3 | XP_068724527.1 | -0.33059986948121 |
Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.
Whether this gene can be visualised in the single-cell atlases of Montipora capricornis, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | ready | open → |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |