Detailed information of XP_074606574.1 in Acropora palmata

Genomic Location: NC_133893.1:676611...693665
NR annotation: XP_044181861.1, disks large homolog 5-like [Acropora millepora]
Species Acropora palmata · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
Q8TDM6Disks large homolog 5 OS=Homo sapiens OX=9606 GN=DLG5 PE=1 SV=4
E9Q9R9Disks large homolog 5 OS=Mus musculus OX=10090 GN=Dlg5 PE=1 SV=1
A0A0G2K2P5Tight junction protein ZO-1 OS=Rattus norvegicus OX=10116 GN=Tjp1 PE=1 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0003781 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF00625
all species →
Guanylate_kinGuanylate kinaseDomainInterproscan
PF00595
all species →
PDZPDZ domainDomainInterproscan
PF07653
all species →
SH3_2Variant SH3 domainDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR036034
all species →
Homologous_superfamilyPDZ superfamilyInterproscan
IPR001478
all species →
DomainPDZ domainInterproscan
IPR008145
all species →
DomainGuanylate kinase/L-type calcium channel beta subunitInterproscan
IPR053004
all species →
FamilyMAGUK Family Regulators of Signaling PathwaysInterproscan
IPR036028
all species →
Homologous_superfamilySH3-like domain superfamilyInterproscan
IPR027417
all species →
Homologous_superfamilyP-loop containing nucleoside triphosphate hydrolaseInterproscan
IPR001452
all species →
DomainSH3 domainInterproscan
IPR011029
all species →
Homologous_superfamilyDeath-like domain superfamilyInterproscan
IPR008144
all species →
DomainGuanylate kinase-like domainInterproscan
IPR001315
all species →
DomainCARD domainInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR46360
all species →
DISKS LARGE HOMOLOG 5Interproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0005515
all species →
Molecular Functionprotein bindingInterproscan
GO:0005886
all species →
Cellular Componentplasma membraneInterproscan
GO:0035331
all species →
Biological Processnegative regulation of hippo signalingInterproscan
GO:0042981
all species →
Biological Processregulation of apoptotic processInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K24050DLG5; discs large protein 5-Hippo signaling pathway - flyko04391deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of XP_074606574.1 across 84 RNA-seq samples of Acropora palmata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

84Samples
79TPM > 0
2Conditions
72.1Max TPM
36.5Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
all_coral_tissue · exposed 46 43 32.06 70.24
all_coral_tissue · baseline 38 36 41.94 72.08

Per sample · hover a bar for the full sample record · show / hide the sample table

Source: CnidoSite RNA-seq expression matrices (APALM_TPM, StringTie quantification over 84 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

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