Gene detail

Detailed information of XP_074609167.1 in Acropora palmata

Genomic Location: NC_133894.1:14839365...14848223
NR annotation: XP_044172187.1, cholesterol 24-hydroxylase-like [Acropora millepora]
Species Acropora palmata · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q9WVK8	Cholesterol 24-hydroxylase OS=Mus musculus OX=10090 GN=Cyp46a1 PE=1 SV=1
Q9Y6A2	Cholesterol 24-hydroxylase OS=Homo sapiens OX=9606 GN=CYP46A1 PE=1 SV=1
Q27589	Cytochrome P450 4d2 OS=Drosophila melanogaster OX=7227 GN=Cyp4d2 PE=2 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0000514 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00067 all species →	p450	Cytochrome P450	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR036396 all species →	Homologous_superfamily	Cytochrome P450 superfamily	Interproscan
IPR002401 all species →	Family	Cytochrome P450, E-class, group I	Interproscan
IPR001128 all species →	Family	Cytochrome P450	Interproscan
IPR039983 all species →	Family	Cholesterol 24-hydroxylase	Interproscan
IPR017972 all species →	Conserved_site	Cytochrome P450, conserved site	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR24293 all species →	CYTOCHROME P450 FAMILY 46 SUBFAMILY A	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0004497 all species →	Molecular Function	monooxygenase activity	Interproscan
GO:0005506 all species →	Molecular Function	iron ion binding	Interproscan
GO:0016705 all species →	Molecular Function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	Interproscan
GO:0020037 all species →	Molecular Function	heme binding	Interproscan
GO:0006707 all species →	Biological Process	cholesterol catabolic process	Interproscan
GO:0033781 all species →	Molecular Function	cholesterol 24-hydroxylase activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K07440	CYP46A1; cholesterol 24-hydroxylase	EC:1.14.14.25	Cytochrome P450	ko00199	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.