Gene detail

Detailed information of XP_074609990.1 in Acropora palmata

Genomic Location: NC_133894.1:18752548...18773630
NR annotation: UCR73892.1, IKKe/TBK1 [Acropora cervicornis]
Species Acropora palmata · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

XP_074609990.1

ATGGAGACCAGAGGCAGCCTAAACTACCAGTGGAATATCAGAGATCAACTAGGACAAGGAGCTACCGGTGCAGTTTTTAAAGGCAGACATAAGAAAACTGGCGAGACTTATGCGATCAAGGTTTCCAACAATTTTGGGATGATGCGTCCCGTGGAAATTCGAAGGAGAGAATATGATGTGCTTTTAAAGTTGCATCATGAGAATATTGTCAAGATTTTTGCAACCGAAGTTGAGATGAGGGGTCAAAATGAAATAATTGTAATGGAACTATGTTCAGGGGGAAGCCTCTTTACAATGCTTGAAAATCCCAGCAATGCTTATGGTTTGCAAGAAGATGAATTCAAGCAAGTAGTCAAAGATGTTGTTGCTGGGATGAAACACCTTCGAGAACAGGGCATTGTGCACAGAGACCTGAAACCTGGCAATATCATGAGGGTGGCAAAAGATGATGGCAGTTTTGTGTACAAATTAACTGATTTTGGTGCAGCCAAAGAGCTGGAAGGTTCTGAAGAGTTCATGTCAATTTATGGAACTGAGGAATATTTGCACCCAGATCTTTATGAAAGAGGTGTACTAAGGAAACATGGCAACAAGGCTTTTAGTGCTACAGTTGACCTGTGGAGTATTGGTGTTACCTTCTATCACATTGCCACAGGGCAGTTACCGTTCAGGCCATATGGGGGAAGGCAAAACAAAGTTACCATGTATGAAATCACTTCAAAGAAAAAGCCAGGTATCATTTCTGGAGTTCAAAAAAGTGAAGGAGAAGAGATTGAATGGAGTGATAAACTTCCAGAGAACACACGCTTGTCACAAGGCCTAAAGGTCTTGTTTACCCCTGTATTAGCAGGTGCATTGGAGTCAGAGCCATGCTCCACATCTATGTCATTTGAACAATTTTTCACCAGTGTACAAGATATTTTGACAAGAAAGGTCATTGACATATATTCAGTGCACTCAGCATGTTTTCACAAGATATACATGAAGCCAAATGAAACATTTGCTAAGTTTCAGGAGCTGATTGCTGTCCAGACTGGAGTTAGTGCCAGGCAGCAAATGTTGATGTTTAAGTATGAAGAGTTTAGGCCAGATCCAATGGCACCTGCTTCATCATATCCTAACACAACGGAACACTCCTTCATGGTCATGATTGGTGGGGATAGCATTTTGCCAGACAGACTTAACTTTTTCAAAATACCAAAAATGCCAAATGTTCCAGAGGAAGGCACTGATCTTGAAAGTGATGCTTCAGTTGCAAAGATAATGACAACTCGGGCACATTACTGCAAATATGCTGTAGAACTGTACACTCGTGCAACAAAAGCAATGCTGCTCACAGTTGAGAGTGTTATAAAAAATCTAAAGAAAGTTATGATGTTGTACATATCATCTTGCAAGCAAGTTGAATCTCAGTCGATTGCTCTTAACCAAACTTGTGATGTTTGTTGTTCCAGTCATGATCACTTGGTGAGGGTCTTCGACACCCTAGTGTCACAATTTACAGAACCGCAAGATAAGATTGAGTCCCTGCAGGAAAAAATTCAAACGATAAAGAAATGGACTGACGCCAAAAGACAGAGTGAAAAAGAGTTGCACAAAATTAATGAGGGACTTCAGCAGTTCAGGGACCTGATATCCAGTGTTGTCGAAAAAGATAGATTCCTTCCATTCTTGGAAGAATTCCGCAGTGATACAGAGAAGGAAAAATTTTTCAACCTAGTTTCAACTTATACCCGAAACACTGCGGACATCTGTACGCTCTTTCGAAAAGATAAAAATCAAAGACGTTTAACTGTCGCGGATAAGCAAAGACATGCGTTTGACCGAAAGAAGATTGTAGTACAGTGCGAAAAGATTACAAGAGTGACAGATGACGCCCTGGGACAAAGAAGCCAGTTACACGCCAAGCTAATTCATTGGCTAAGTGAGGTAGATACCTGTACCGAGGAGGCTGAGAATCTTCAGAATTCGTTTGTTGTTCACACGGAAGCAATGGAGGCCCATCGCATATCCTTGCAAACACTTCAAGAACAATGTCAAGTGAAATCCAAAGAGATTTTACAGGAGATTCAACAACTTCAAAGCTTGACAACATCAAACGTTGCTTCACATCCTGGGTCATCCTCTCCTGTGCTGAATGGTCATGAAGAACAGGAAGAGCAAATATTGACTGACACTATGCAAGCACTTGGATATGAATTGGACACCTTGTCAGACATCACAACGGCATCTCTGGGAACAGCTAAAGACAACACTGCACAAATTGAAAGGCTTATAAGCGGCTTAATCAAATCTTATGAATCTATGAATGACCACCTGAAGAAAAACTTTGAACAATTAGTTGAAGCAGTGAGAGGAGAAGCAGATCACCTACAGTAG

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q9UHD2	Serine/threonine-protein kinase TBK1 OS=Homo sapiens OX=9606 GN=TBK1 PE=1 SV=1
Q6DFJ6	Serine/threonine-protein kinase TBK1 OS=Xenopus laevis OX=8355 GN=tbk1 PE=2 SV=1
Q9WUN2	Serine/threonine-protein kinase TBK1 OS=Mus musculus OX=10090 GN=Tbk1 PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0003057 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF18396 all species →	TBK1_ULD	TANK binding kinase 1 ubiquitin-like domain	Domain	Interproscan
PF18394 all species →	TBK1_CCD1	TANK-binding kinase 1 coiled-coil domain 1	Coiled-coil	Interproscan
PF00069 all species →	Pkinase	Protein kinase domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR051180 all species →	Family	Inhibitor of nuclear factor kappa-B kinase	Interproscan
IPR041087 all species →	Domain	TANK binding kinase 1, ubiquitin-like domain	Interproscan
IPR041309 all species →	Domain	TANK-binding kinase 1, coiled-coil domain 1	Interproscan
IPR000719 all species →	Domain	Protein kinase domain	Interproscan
IPR011009 all species →	Homologous_superfamily	Protein kinase-like domain superfamily	Interproscan
IPR017441 all species →	Binding_site	Protein kinase, ATP binding site	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR22969 all species →	IKB KINASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0004674 all species →	Molecular Function	protein serine/threonine kinase activity	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0018105 all species →	Biological Process	peptidyl-serine phosphorylation	Interproscan
GO:0004672 all species →	Molecular Function	protein kinase activity	Interproscan
GO:0005524 all species →	Molecular Function	ATP binding	Interproscan
GO:0006468 all species →	Biological Process	protein phosphorylation	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K05410	TBK1; TANK-binding kinase 1	EC:2.7.11.10	Membrane trafficking	ko04131	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of XP_074609990.1 across 84 RNA-seq samples of Acropora palmata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

84Samples

80TPM > 0

2Conditions

112.3Max TPM

57.7Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM	Mean, relative to max
all_coral_tissue · exposed	46	45	53.02	112.32
all_coral_tissue · baseline	38	35	63.44	95.84

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR8800075	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	112.32
SRR8800105	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	108.16
SRR8800042	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	96.97
SRR8800039	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	85.41
SRR8800073	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	81.44
SRR8800077	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	77.32
SRR8800080	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	77.24
SRR8800068	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	72.32
SRR8800100	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	71.66
SRR8800083	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	70.94
SRR8800066	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	70.61
SRR8800097	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	70.44
SRR8800036	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	67.27
SRR8800099	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	65.26
SRR8800051	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	61.81
SRR8800038	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	59.40
SRR8800093	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	58.60
SRR8800045	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	56.01
SRR8800034	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	55.28
SRR8800071	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	52.04
SRR8800056	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	50.34
SRR8800028	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	47.27
SRR8800047	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	46.92
SRR8800065	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	46.85
SRR8800060	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	45.91
SRR8800092	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	45.81
SRR8800091	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	45.36
SRR8800062	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	44.93
SRR8800044	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	44.03
SRR8800063	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	43.48
SRR8800107	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	42.75
SRR8800079	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	42.62
SRR8800040	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	41.74
SRR8800061	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	38.00
SRR8800088	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	37.54
SRR8800033	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	36.59
SRR8800095	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	36.05
SRR8800094	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	33.99
SRR8800087	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	33.54
SRR8800053	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	32.14
SRR8800026	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	31.15
SRR8800089	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	31.02
SRR8800058	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	26.60
SRR8800029	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	25.72
SRR8800027	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	18.21
SRR8800086	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	0.00
SRR8800067	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	95.84
SRR8800078	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	95.33
SRR8800098	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	94.20
SRR8800043	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	91.59
SRR8800057	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	91.22
SRR8800041	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	90.01
SRR8800101	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	89.42
SRR8800076	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	89.42
SRR8800069	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	86.53
SRR8800109	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	82.47
SRR8800074	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	82.28
SRR8800096	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	81.49
SRR8800072	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	80.85
SRR8800032	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	80.04
SRR8800035	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	77.76
SRR8800106	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	77.45
SRR8800102	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	74.68
SRR8800048	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	74.27
SRR8800104	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	69.81
SRR8800049	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	68.41
SRR8800081	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	64.49
SRR8800055	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	63.56
SRR8800037	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	61.29
SRR8800031	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	56.41
SRR8800108	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	55.69
SRR8800050	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	51.04
SRR8800103	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	50.58
SRR8800082	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	49.64
SRR8800059	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	46.74
SRR8800084	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	40.95
SRR8800030	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	40.91
SRR8800085	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	40.17
SRR8800090	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	39.91
SRR8800070	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	39.31
SRR8800064	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	37.02
SRR8800046	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	0.00
SRR8800052	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	0.00
SRR8800054	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	0.00

Source: CnidoSite RNA-seq expression matrices (APALM_TPM, StringTie quantification over 84 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.