Gene detail

Detailed information of XP_074616626.1 in Acropora palmata

Genomic Location: NC_133884.1:9728698...9747472
NR annotation: XP_029195943.2, eukaryotic translation initiation factor 2-alpha kinase 1-like [Acropora millepora]
Species Acropora palmata · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

XP_074616626.1

ATGGCTTCCAACACAAGGTCGAAGTGGACACGTTCAAGACTTGAGTCCCCTGGACTTCCTTCCCGCTTGACCGAGTTTCAAGATTCTGATTCCTCGGAGACATTCATAGCAAGAAATGATCCCACCTCTAGCATTCAAGCGTTGGAGGGTCGTGTGCCAAACTATCTCCTATTAGTGTCGTTACTTGAACAGCTGTGTTCCTTGTATGAGGGTGACTCTGAAAAGAGCAATAAGATCTTTACTGTTCTCTGTCAACAACTTGTGAAGATGAAGGTCATGCCTTCATTTTCATTTTTGGAAGAGTTCAGTGTTATCAGAGCAAAGTACAAGACAGTATTCAGTGATCTCATGCAAGCTGCTGCTAGGACCACTGGCACAGATTTGCATAAATTCCCTTTGGCTACAAGAAGACCAATGCTTAACCCATTTCCAGCTCACAAGTCCTTGTCAGCTCCTCCAAAAATGAGCGATTTGATGCAAAATGTTTCTTCACGCTACAAAGAAGAGTTTGTGGAGATTGCAAGAATTGGGAAAGGAGGCTTTGGGAGTGTTTTTAAGGTTAAGAACAAATTGGATGGGAGAGAATATGCTGTGAAAAAAATTCCCTTGAAGGAAACTGATCCAGATCTTTGGTTAAAGGTCCTTCGAGAAGTTAAAGTGTTGGCACACTTAAGCCATAACAACGTGGTCGGTTACCATGGAGCCTGGTTGGAATATGTTACAACCGATAATATTGAATATGCAATACCAAGGGTCGCTACTCTTCCAACCAGCCTCAAGGAACTTTGCGACTTTTCTTCCCTGAATGGAATTCAGAGAATCATGGAAGTAAGCTGCTCAGACAGCCAAAACAGCATAGTGTTTGAAGGCTCGTCCCAAGATATCTCCAATGGAGGGATCTCATTCGCTGCTTGCAGATCAAGTAATGACTCTTTTGGGACTGGAACCAAATCACATGGTGCTCAAGCCGGTTGTCAACCGGGAAAGAGTCCCAGGAGTAGCACCAATAGTAGTCGAAGTAGCAAGGCTCCGTATTTGACGTCACAGCGGAGCATGCGCCGATCGGCCTCCAGCAGTAGCTTGGGGTCCTTGGCAGGTAAAGATGGCGTTCGATCAGGTGAGGAGCCAAGCGATCCCAGTGAAAGGAGCAATGCGATATCAGGGAACATTGAGGGAAACACGACACGTCACAAGCGTCTCGGAATGGTACTCTTCATACAGATGCAACTTTGTACCACAACACTCCGTGACTGGCTTGTCAAGCGAAACGATGACGTTTTACGTACAGGCGAGGAAGTCGACGAAGAAGCCGCTATGGAGATATTCCGTCAGCTCCTTGAAGGCGTGCGGTACATTCACTCTGAGGATGTGCTTCACCGGGATCTCAAGCCGAGGAATATCTTTCTTCAATGGCTTTTACAAAAGGCAGATGACAGGCCAATAAGATTTCAGGTTAAAATCGGTGACTTTGGCTTGGCGCGAAAAGAAGCCGTGGTGAGCCCTGGGGCGGGCAGTCCGCTGGCCAGTTTAATTGAACCGCACTCACCTCTTTTTAATCCAGGATTTTCAAAAAAACATGCCGCTACCGCAGGCGTTGGTACATGTACTTATGCATCGCCCGAACAACTTAGAGACAACAACTACGATAACAAGGCAGATATATTCAGTTTGGGGATCATCTTGTTTGAACTGTTTTGTTCCTTTGGCACCGAGATGGAACGCGTAACGAGCATCAAAGATATTAGACAATGCAGACTACCGCAAGAGTTTTGCCAGAGGTGGCCTGAAGTGGCCAAGCTCATCACAGAGATGACTGCTGAAAGACCGGACGATAGACCAACAGCTGAAACACTGCTAGAGACTGGACTTTTCAAAGAAAAGCACGTGCATATCGGGCATCATCTCAACGAAAGAGTCGAACAACAAGCGTCCGAAATAGCGGAACTGAAGGCTTTGCTCTCACAGAAGAACAGTGAAGTGCAAACCAGAGAAGAAGAGATTAGCGATCTTAAGCGACAATTGGAGAAGAATGACGAATTTTTAAAGCGAATATTTGACAACTTGTGCTCAGCGTGCAATAAAAAGATAGGCAGTCAAGTGGAAGAAATGGACACTGGATGA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q63185	Eukaryotic translation initiation factor 2-alpha kinase 1 OS=Rattus norvegicus OX=10116 GN=Eif2ak1 PE=1 SV=2
Q9Z2R9	Eukaryotic translation initiation factor 2-alpha kinase 1 OS=Mus musculus OX=10090 GN=Eif2ak1 PE=1 SV=2
Q9BQI3	Eukaryotic translation initiation factor 2-alpha kinase 1 OS=Homo sapiens OX=9606 GN=EIF2AK1 PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0005007 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00069 all species →	Pkinase	Protein kinase domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR000719 all species →	Domain	Protein kinase domain	Interproscan
IPR050339 all species →	Family	Cell Cycle and Stress Response Kinase	Interproscan
IPR017441 all species →	Binding_site	Protein kinase, ATP binding site	Interproscan
IPR008271 all species →	Active_site	Serine/threonine-protein kinase, active site	Interproscan
IPR011009 all species →	Homologous_superfamily	Protein kinase-like domain superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR11042 all species →	EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0004672 all species →	Molecular Function	protein kinase activity	Interproscan
GO:0005524 all species →	Molecular Function	ATP binding	Interproscan
GO:0006468 all species →	Biological Process	protein phosphorylation	Interproscan
GO:0004694 all species →	Molecular Function	eukaryotic translation initiation factor 2alpha kinase activity	Interproscan
GO:0005634 all species →	Cellular Component	nucleus	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0005829 all species →	Cellular Component	cytosol	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K16194	EIF2AK1; eukaryotic translation initiation factor 2-alpha kinase 1	EC:2.7.11.1	Protein kinases	ko01001	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of XP_074616626.1 across 84 RNA-seq samples of Acropora palmata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

84Samples

72TPM > 0

2Conditions

64.1Max TPM

25.7Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM	Mean, relative to max
all_coral_tissue · exposed	46	40	25.50	64.11
all_coral_tissue · baseline	38	32	25.89	40.80

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR8800105	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	64.11
SRR8800056	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	47.72
SRR8800077	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	45.56
SRR8800097	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	41.63
SRR8800092	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	41.57
SRR8800044	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	41.48
SRR8800051	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	40.87
SRR8800100	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	40.42
SRR8800068	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	38.42
SRR8800099	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	37.84
SRR8800071	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	37.18
SRR8800034	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	36.94
SRR8800036	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	36.53
SRR8800039	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	35.58
SRR8800053	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	35.11
SRR8800093	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	32.86
SRR8800080	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	32.19
SRR8800079	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	31.55
SRR8800073	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	31.50
SRR8800038	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	30.82
SRR8800083	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	29.27
SRR8800033	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	27.21
SRR8800091	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	26.13
SRR8800045	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	25.90
SRR8800107	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	25.13
SRR8800062	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	23.77
SRR8800028	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	23.43
SRR8800063	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	23.14
SRR8800060	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	20.71
SRR8800095	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	19.24
SRR8800047	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	19.11
SRR8800040	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	17.52
SRR8800058	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	17.05
SRR8800065	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	16.85
SRR8800088	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	16.74
SRR8800087	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	14.78
SRR8800061	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	14.39
SRR8800026	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	12.83
SRR8800089	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	11.89
SRR8800027	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	7.82
SRR8800029	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	0.00
SRR8800042	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	0.00
SRR8800066	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	0.00
SRR8800075	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	0.00
SRR8800086	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	0.00
SRR8800094	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	0.00
SRR8800074	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	40.80
SRR8800067	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	40.68
SRR8800096	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	39.13
SRR8800098	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	37.57
SRR8800082	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	37.08
SRR8800032	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	36.55
SRR8800081	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	35.57
SRR8800076	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	35.27
SRR8800057	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	35.20
SRR8800069	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	35.07
SRR8800072	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	34.91
SRR8800078	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	34.12
SRR8800043	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	33.89
SRR8800048	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	33.31
SRR8800050	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	32.56
SRR8800035	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	32.46
SRR8800031	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	31.99
SRR8800070	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	31.44
SRR8800041	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	30.37
SRR8800101	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	29.96
SRR8800037	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	28.93
SRR8800054	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	27.93
SRR8800049	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	27.85
SRR8800102	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	27.38
SRR8800090	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	26.77
SRR8800108	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	25.27
SRR8800109	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	24.49
SRR8800103	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	23.18
SRR8800104	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	20.35
SRR8800085	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	19.82
SRR8800064	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	17.41
SRR8800084	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	16.34
SRR8800030	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	0.00
SRR8800046	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	0.00
SRR8800052	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	0.00
SRR8800055	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	0.00
SRR8800059	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	0.00
SRR8800106	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	0.00

Source: CnidoSite RNA-seq expression matrices (APALM_TPM, StringTie quantification over 84 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.