Genomic Location: NC_133884.1:12302724...12303108
NR annotation: XP_001618258.1, histone H4 [Nematostella vectensis]
Species Acropora palmata · all data for this species · gene families
| CDS |
| XP_074618993.1 |
| Protein |
| XP_074618993.1 |
| UniProt accession | Description |
|---|---|
| P35059 | Histone H4 OS=Acropora formosa OX=126732 PE=3 SV=2 |
| Q6LAF1 | Histone H4 OS=Dendronephthya klunzingeri OX=84964 GN=H4DEKL PE=3 SV=3 |
| P62803 | Histone H4 OS=Bos taurus OX=9913 PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0000558 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF15511 all species → | CENP-T_C | Centromere kinetochore component CENP-T histone fold | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR001951 all species → | Family | Histone H4 | Interproscan |
| IPR009072 all species → | Homologous_superfamily | Histone-fold | Interproscan |
| IPR019809 all species → | Conserved_site | Histone H4, conserved site | Interproscan |
| IPR004823 all species → | Domain | TATA box binding protein associated factor (TAF), histone-like fold domain | Interproscan |
| IPR035425 all species → | Domain | CENP-T/Histone H4, histone fold | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR10484 all species → | HISTONE H4 | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0003677 all species → | Molecular Function | DNA binding | Interproscan |
| GO:0006334 all species → | Biological Process | nucleosome assembly | Interproscan |
| GO:0030527 all species → | Molecular Function | structural constituent of chromatin | Interproscan |
| GO:0046982 all species → | Molecular Function | protein heterodimerization activity | Interproscan |
| GO:0000786 all species → | Cellular Component | nucleosome | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K11254 | H4; histone H4 | - | Chromosome and associated proteins | ko03036 | deepkoala |
Transcript abundance of XP_074618993.1 across 84 RNA-seq samples of Acropora palmata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| all_coral_tissue · exposed | 46 | 30 | 1.73 | 20.32 | |
| all_coral_tissue · baseline | 38 | 22 | 1.37 | 14.66 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| SRR8800086 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 20.32 |
| SRR8800027 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 7.52 |
| SRR8800056 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 6.99 |
| SRR8800026 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 5.69 |
| SRR8800029 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 5.43 |
| SRR8800061 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 2.48 |
| SRR8800068 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 2.15 |
| SRR8800107 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 2.03 |
| SRR8800077 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 2.03 |
| SRR8800058 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 1.90 |
| SRR8800033 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 1.81 |
| SRR8800088 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 1.75 |
| SRR8800044 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 1.66 |
| SRR8800051 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 1.52 |
| SRR8800047 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 1.46 |
| SRR8800080 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 1.45 |
| SRR8800036 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 1.39 |
| SRR8800087 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 1.38 |
| SRR8800060 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 1.34 |
| SRR8800095 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 1.27 |
| SRR8800073 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 1.26 |
| SRR8800063 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 1.17 |
| SRR8800089 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 1.14 |
| SRR8800040 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.87 |
| SRR8800062 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.70 |
| SRR8800083 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.70 |
| SRR8800038 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.63 |
| SRR8800097 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.56 |
| SRR8800053 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.50 |
| SRR8800093 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.39 |
| SRR8800028 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800034 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800039 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800042 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800045 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800065 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800066 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800071 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800075 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800079 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800091 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800092 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800094 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800099 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800100 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800105 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800054 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 14.66 |
| SRR8800090 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 7.98 |
| SRR8800031 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 5.17 |
| SRR8800104 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 4.15 |
| SRR8800067 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 3.71 |
| SRR8800085 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 3.17 |
| SRR8800076 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 2.04 |
| SRR8800041 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 1.68 |
| SRR8800057 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 1.56 |
| SRR8800103 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 1.37 |
| SRR8800050 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.94 |
| SRR8800043 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.90 |
| SRR8800069 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.81 |
| SRR8800048 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.79 |
| SRR8800037 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.70 |
| SRR8800081 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.64 |
| SRR8800072 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.44 |
| SRR8800049 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.36 |
| SRR8800101 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.30 |
| SRR8800102 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.27 |
| SRR8800084 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.25 |
| SRR8800070 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.24 |
| SRR8800030 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800032 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800035 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800046 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800052 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800055 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800059 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800064 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800074 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800078 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800082 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800096 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800098 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800106 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800108 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800109 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
Source: CnidoSite RNA-seq expression matrices (APALM_TPM,
StringTie quantification over 84 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
Genes whose expression across the transcriptome samples of Acropora palmata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
| Direction | Partners | Most correlated partner | PCC |
|---|---|---|---|
| Positively correlated | 1 | XP_074618379.1 | 0.748431772667305 |
| Negatively correlated | 45 | XP_074625643.1 | -0.600021319538642 |
Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.
Whether this gene can be visualised in the single-cell atlases of Acropora palmata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
| Sample | Methylation profile |
|---|---|
| Polyp_Underside_Control_2 | open |
| Polyp_Underside_Control_3 | open |
| Polyp_Underside_Treatment_1 | open |
| Polyp_Upperside_Control_1 | open |
| Polyp_Upperside_Treatment_3 | open |
| Polyp_Upperside_Treatment_4 | open |
The DNA Methylation page locates this gene by scanning the bisulphite table, which holds one row per cytosine. For the largest datasets that scan takes a while to return; it does not mean the link is broken.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | ready | open → |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |