Gene detail

Detailed information of XP_074622131.1 in Acropora palmata

Genomic Location: NC_133886.1:1029223...1038168
NR annotation: XP_029190468.2, lysosomal alpha-mannosidase-like isoform X1 [Acropora millepora]
Species Acropora palmata · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

XP_074622131.1

ATGTCGCTTGTCGTCTGTTTTCTAACACTGCTTGGTTTTGGTTCAGGATTTGCTTGTAAGTTTGATGGAACAGTGGCAGACGAGGCCACACTGCAAGTCCATCTTGTTCCACATTCACATGACGATGTAGGTTGGTTGAAAACTGTGGATCAATACTTCTATGGAGCTAATAATTCCATCCAGCACGCTGGTGTCCAGTATATATTGGATTCAGTCATCCCACAATTGATGGCAGATCCTTTGAAACGTTTTATTTACGTGGAAATCGCGTTTTTCGAGCGATGGTGGAACGAACAAAGCGAAACTATGAAAGCCGAAGTGAAAAAGCTCGTTGCCGACAGAAGACTTGAGTTTATAAACGCAGGATGGTGTATGAACGATGAGGCAGCCACACATTACAATGGAATTATTGATCAAATGACTTACGGCTTAAACTTTGTGCAAGAAACATTTGGTTCCGACGCGAGGCCGAGAATAGCTTGGCATATAGACCCGTTTGGTCACTCCAACGAACAAGCCTCTATCTTCTCTCAAATGTCATTCGATGGATTCTTCTTTGGTCGAATTGATTACCAGGATAAAGATGTTCGTCTTAAGCAACAGAGGATGGAAATGGTGTGGAGAGGAAGCAAAAGTCTTGGAAAAGGCTCGGACATTTTTACTGGCGTGCTTTTCAATGTCTACAATCCACCCAAAGGATTTTGCTATGACCAGTTTTGTGCAGATCCCCCTGTTCAAGATGACCCAAACCTCTATGACCTCAATATCAAGGAAACGGTGAACAAATTTGTTGCCACAACATGTGAACAAGCTTCACACTACAAAACCAACAACATCATGTTGACAATGGGTTCAGATTTTATGTACGAAAATGCTAATTTGTGGTACAAGAATTTGGACAAACTTATAAGATATGTAAATGAAGATGGCCGTGTGAATGCATTCTACTCTACGCCAACCATATACTTGGATGCACTTCACAAAGCCAACCAGACATGGGGATTGAAGACTGATGACTTTTTTCCATACGCTGACTGTCCACACTGTTACTGGTCTGGTTATTTCACCAGCCGACCAGCACTCAAGCGATACATCAGGCTCAACAACAACTTACTCCAGGTTTGTAAACAATTGGAGTTAATAAATGGCCCTGAAAGAGGCAATAACAAATCTTCTGATACTTTACGCCGAGCAATGGGTGTGGTTCAACACCATGATGCTGTTACTGGAACATCCAAACAACATGTGGCTGATGATTATGCGAAGCGACTTGCCATTGCTGCTGTTGAATGCCAGGGTTTGATAACGGATGTCCTGGGAAATATGGTAGTGAAAAGCAAAGGAATTCAACACCCTGTCATGAAATTCTGCGACCATCTTAACATAAGCGTCTGTGCAGACACCGAACTGAAAAAAGCCTTTACAGTGACAATTTACAACGCCATTGCAAGAGAAGTGAATACAATTGTCCGACTTCCGTTGGCAGTGAGCACAATGGCTGTGTATGGTCCCAAGGGACATCCAGTTGCAAGCCAAATTCTGCCTATTTCTGATGCTACAAAACAGGTGCAAATTCTACAAAATCAGAAGCAAAGCCGGTCAGCTTTTGAGATTATGTTTGAAGCTAATGTTCCGGCCCTGGGCTTCGCCACTTATTTCATCAATTCAACCCAACATCGGTCTCATTTAGATAAACCTTTCGGATCATCCCCGAAGAAAGCCCCGAAGAAGTCCGAGGACACATCGATCGAAAATGAACACATCACACTGACGTTTTCTTCCGACACTGGCCTGTTGACGAGCATGACAGATAAGAGTTCAAAAGTGACCACTAAACTGACCCAAGCATTTTATTGGTACAACGCCAGCGAAGACCACAACCAGCCTTCTGGTGCATACATCTTTAGACCCAACAAAAGTCAACCGATTTCATTCCCGCAACCGGTGAAGACAAAATTGTTTAAGGGTTCCTTGGTGCAAGAGATTCGACAGGACATTTCACCCTTCATAAGTCAAGTGGTCAGGCTTTATGTTGGACAGCGGCATGCCGAGTTCGAATACACAGTGGGACCCATTCCCGTTGCGGATAATTGGGGCAAAGAGATCATCACTCGTTTCGACTCCGATATTCAATCCAATCAGGTTTTCTTCACTGATGCGAATGGAAGGGAAATGCAAGAACGCAAAGTGAATTACCGTCCCACCTGGAATCTAACCGTCACGGAACCAGTGGCTGGTAATTATTATCCAGTGAATAGTCGAATGTACATCAAAGACGCAGCTAAACAGCTGACAGTTCTGACTGACCGCTCCCTGGGTGGGTCGAGCCTCAAGGCTGGGTCAATGGAAATCATGCTTCATAGGCGACTGTTGGTAGATGACAAGAGAGGGGTGGGTGAAGCATTAAACGAGACTGGCATCTCTGGAAAGGGTTTGATTGTTCGAGGCAAGCTTTGTGTTATTCTGGCGCCTCCCCAGTCTTCTGCAGCTTTGCATCGTGAACTTGGAGAAAAGCTGTTGTTAGAACCCCTACTCGCCTTCGCCCCAAACAGCCTCACTTTTGAGAAATGGACGGGAGTCTACAACTCACTGCACAGCGGTCTTACACGTGAGCTACCGCTTAACGTTCATTTGCTGACCTTGGAAACTTCAAAGGACTTGGCCCTGATCCGCGTTGAGCATCAGTACGAGGTTGGCGAAGACGCTAAGCTGTCACAACCCGTCAACATTTCATTGGCGGGGCTTTTTACCAATTTTGATGTCGAGTCCATGACGGAAATGAATCTGTCTGCCAATCAACTGCTCAAGGACAAACGACCTCTTCAATGGAACATTAAAAGAGGAGCGAAAAACGAAAACGAAGGGCGAAAAAGGAATTCTGGGGCTCGTTCACCAACTGATTTGAATGTGGAGCTTAGTCCAATGCAGATACGCACCTTCAAGGCTGTTATCAAACGCCATATTGGAAATTAA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q60HE9	Lysosomal alpha-mannosidase OS=Macaca fascicularis OX=9541 GN=MAN2B1 PE=2 SV=1
O00754	Lysosomal alpha-mannosidase OS=Homo sapiens OX=9606 GN=MAN2B1 PE=1 SV=3
O46432	Lysosomal alpha-mannosidase OS=Felis catus OX=9685 GN=MAN2B1 PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0002052 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF07748 all species →	Glyco_hydro_38C	Glycosyl hydrolases family 38 C-terminal domain	Domain	Interproscan
PF01074 all species →	Glyco_hydro_38N	Glycosyl hydrolases family 38 N-terminal domain	Domain	Interproscan
PF09261 all species →	Alpha-mann_mid	Alpha mannosidase middle domain	Domain	Interproscan
PF21260 all species →	Laman-like_dom	Lysosomal alpha-mannosidase-like, central domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR027291 all species →	Homologous_superfamily	Glycoside hydrolase 38, N-terminal domain superfamily	Interproscan
IPR013780 all species →	Homologous_superfamily	Glycosyl hydrolase, all-beta	Interproscan
IPR011682 all species →	Domain	Glycosyl hydrolase family 38, C-terminal	Interproscan
IPR015341 all species →	Domain	Glycoside hydrolase family 38, central domain	Interproscan
IPR000602 all species →	Domain	Glycoside hydrolase family 38, N-terminal domain	Interproscan
IPR011330 all species →	Homologous_superfamily	Glycoside hydrolase/deacetylase, beta/alpha-barrel	Interproscan
IPR050843 all species →	Family	Glycosyl Hydrolase Family 38	Interproscan
IPR028995 all species →	Homologous_superfamily	Glycoside hydrolase families 57/38, central domain superfamily	Interproscan
IPR037094 all species →	Homologous_superfamily	Glycoside hydrolase family 38, central domain superfamily	Interproscan
IPR011013 all species →	Homologous_superfamily	Galactose mutarotase-like domain superfamily	Interproscan
IPR048534 all species →	Domain	Lysosomal alpha-mannosidase-like, central domain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR11607 all species →	ALPHA-MANNOSIDASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0004559 all species →	Molecular Function	alpha-mannosidase activity	Interproscan
GO:0006013 all species →	Biological Process	mannose metabolic process	Interproscan
GO:0005975 all species →	Biological Process	carbohydrate metabolic process	Interproscan
GO:0005764 all species →	Cellular Component	lysosome	Interproscan
GO:0003824 all species →	Molecular Function	catalytic activity	Interproscan
GO:0030246 all species →	Molecular Function	carbohydrate binding	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K12311	MAN2B1, LAMAN; lysosomal alpha-mannosidase	EC:3.2.1.24	Lysosome	ko04142	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of XP_074622131.1 across 84 RNA-seq samples of Acropora palmata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

84Samples

81TPM > 0

2Conditions

107.7Max TPM

43.0Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM	Mean, relative to max
all_coral_tissue · exposed	46	44	36.79	79.52
all_coral_tissue · baseline	38	37	50.63	107.74

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR8800042	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	79.52
SRR8800056	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	78.40
SRR8800051	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	75.82
SRR8800077	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	74.18
SRR8800105	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	71.16
SRR8800097	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	69.13
SRR8800066	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	68.44
SRR8800099	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	63.26
SRR8800100	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	62.84
SRR8800039	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	57.18
SRR8800068	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	56.04
SRR8800044	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	53.48
SRR8800071	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	53.09
SRR8800036	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	53.00
SRR8800093	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	51.61
SRR8800092	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	50.09
SRR8800080	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	49.69
SRR8800083	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	49.59
SRR8800038	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	48.39
SRR8800079	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	47.48
SRR8800053	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	44.99
SRR8800086	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	42.81
SRR8800045	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	37.60
SRR8800047	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	29.61
SRR8800034	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	29.53
SRR8800060	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	28.27
SRR8800073	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	26.39
SRR8800091	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	25.45
SRR8800063	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	22.09
SRR8800033	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	20.82
SRR8800058	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	20.56
SRR8800107	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	19.79
SRR8800061	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	16.04
SRR8800027	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	14.71
SRR8800026	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	14.20
SRR8800065	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	13.39
SRR8800094	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	12.67
SRR8800029	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	11.74
SRR8800088	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	10.76
SRR8800062	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	10.37
SRR8800040	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	9.43
SRR8800095	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	7.97
SRR8800087	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	5.31
SRR8800089	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	5.21
SRR8800028	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	0.00
SRR8800075	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	0.00
SRR8800052	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	107.74
SRR8800106	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	94.46
SRR8800057	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	91.44
SRR8800078	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	80.73
SRR8800096	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	74.75
SRR8800048	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	73.12
SRR8800069	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	71.50
SRR8800109	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	71.11
SRR8800098	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	70.19
SRR8800104	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	70.03
SRR8800041	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	65.76
SRR8800076	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	65.50
SRR8800082	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	64.92
SRR8800074	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	64.43
SRR8800050	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	63.56
SRR8800101	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	62.31
SRR8800043	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	56.96
SRR8800072	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	56.18
SRR8800067	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	52.01
SRR8800108	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	51.81
SRR8800035	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	51.64
SRR8800081	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	51.39
SRR8800037	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	50.22
SRR8800049	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	47.32
SRR8800032	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	44.74
SRR8800103	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	42.49
SRR8800031	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	37.16
SRR8800059	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	31.71
SRR8800102	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	26.36
SRR8800084	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	25.17
SRR8800055	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	23.36
SRR8800030	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	19.74
SRR8800070	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	19.21
SRR8800054	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	13.92
SRR8800064	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	13.64
SRR8800090	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	8.93
SRR8800085	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	8.51
SRR8800046	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	0.00

Source: CnidoSite RNA-seq expression matrices (APALM_TPM, StringTie quantification over 84 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.