Gene detail

Detailed information of XP_074622293.1 in Acropora palmata

Genomic Location: NC_133886.1:384007...398757
NR annotation: XP_029179461.2, helicase POLQ-like isoform X1 [Acropora millepora]
Species Acropora palmata · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

XP_074622293.1

ATGGAAAGTTTCAAAAGGGAAGCACAGGCACTTCCAATGAATGATAAAAAACGTTCTTGCAATGGTTTACTCTCGGTGAAGAAGATTAACTTCAATAGAAGCAATAGCAAATGTGCAATAGACAGAGAAGATGTGTTTGCAGGAGGTGAAATGCAAACGAACTGTAGTTCGAACACAGCAAGAAAGAGGAGGTCAAGACGGGTTAACTCGCGAAGTGGTCTTTGCACAAGAGATGTCGGCCCTGAGAAACTGACTTGCATTTCAGAGGCGATCGATGTTCCCCACGTGAGCATGATCGTGGAAGAAGACGTGAAAGACTCTTCAGATGTTCTTTGTAGGGCTGAACAAAGAGCAGTTTTCAATACTCCAAGAGGTGATGACATGGTCAATGGCTTCTCACCCTTTTCTAAGAGTTTTCATGTGGGAAAGCACTCTCCCTTTGGAACTGGCGTTGCAAGCTTGATAAACAATACCAGTTTCTACGAGGACGATGTGGCCTTAGCCTCTCTGAACTTAAGTGAAATTGTAACATCATCCTCTCCTTCGTCAAATGATTTGGTGGATGACAGCTGTCAGTTTTATGGGTTGCCAATGAAAGTCAAAGAAATGTTACACAAATTCAAGGGAATAGAAACCTTATATGACTGGCAAATCCACTGTCTTAGTCTGCCAGCAGTCAAGGAAAGAAGAAATTTGATTTACTCTCTACCCACAAGTGGAGGAAAGACATTGGTGGCAGAAATTCTTATTTTCAGAGAATTATTGTTGCAAGAAAAGGATGTCCTATTTATCCTTCCATTCGTTTCCATTGTACAGGAAAAAGTGAAATCATTGAGCCAATTTGCTATTGAGCTTGGGTTTTTAGTAGAGGAATATGCTGCCAGCCATGGGAAACTCCCTCCACGCCAGAGACGCAAGAAGAAATCTGTATATGTAGCCACAATAGAAAAGGCAAATGCCCTGGTCAATAGTCTTATTGGAGAAAACCGGATATCCACATTAGGTCTGGCAGTGGTAGATGAGCTGCATATGTTAGGTGAGGTTGGACGAGGAGCAACTTTGGAGATGTGTCTATCCAAGCTCATGTTTGCATCCTCTCTTACCCAAATAATTGCAATGAGTGCAACTTTGAGCAACATTGGAGACCTGAAGCACTTTTTAAAGGCAGATGTTTACTCCAATGACTTTAGACCTGTGGAATTGAAAGAATACTATAAAATGGGCCATGATATCTATGAAGTACCAAAAGCTTCAGACCCTGTTGATAAAATTTACAAGCCTATGAAAACAATCAGACATAACCAGGATCAAAACAAGGATTTGTTAGCGCAGGATCCAGATCAGTTATTACCTCTTGTGTTGGAAGTCATCCCTAAGCACTCATGTCTGATATTTTGTTCAACTAAGAAGAACTGCCAAAATTTAGCACTGCTTCTGGTAAAATTTATGCCCAGATATTTGATCCAAGTCAAAGCCAACGAAAGGCATCAGCTTATGAAAGCTTTGTACAGTGAAGTAAGCGCACTTTGCCCTGTCTTAAAAGCAACCATTCCATTTGGTCTAGCTTATCACCACAGTGGACTGACAATGGATGAACGCAAATTGATTGAAGATGCCTACAGCCAGGGTGTGCTCTGTCTTTTGACTTGTACCTCTACACTGGCAGCTGGGGTTAATTTGCCAGCAAAGAGAGTGATTGTTCGGGCACCATATGTTGGAAATGCGTTAGTAAGTCAAAGCCAGTATAAGCAGATGATTGGCAGAGCTGGACGAGCTGGTATCGACACTTCAGGAGAGAGTATACTTATTATCAAGGAAGCTGATAAACCAAAGATTAGTCACCTGTTTTCAGGGCCAGTGGAAAAATGTCTTAGTAGATTACTAGTTGAAAACAGGAAAGGATTACAATCCTTGGTTCTCACTCTTATTGGTCTGAAGATATGTGGGACAGTTAGTGAACTAAAAGAGTTTATGCATCAAAGCACATTGCTGTTTGTCCAATCAGAATGTCAGTCAGTGGACATTGATGAACAGGTGGAAACATGTATCCAGTCGCTGAAACAACTTGGACATGTTACAGTATCAAACAGCTTCAAGACAGAGGTGACTCAACTTGGACAAGCAACTTTTAAAGGTTGCATTGATGTGGAAAGCAGTCCTGTAATCTATCAAGAGCTTGAGCGTGCCCATAAAAGCTTGGCCTTGGACAATGAACTTCATCTACTCTATCTTGTGACACCGCTGAATATGAAGGATTTAATTGAACCAGACTGGATGACTTACTTTAGACAGGTAATATCATTAAACGATTCAGAGCAGGAGGTTGCTCGTTTGGTGGGAGCCACAGAAAGCATTTTATCAAGAAAAGCTTCCGGTTTAAGAGTCAAGAAGAATGATAGGGACAGCGAGACACCATTGAAGCGTTTCTATTTGACTCTCATTCTTCATAAACTGATGAAAGAACACACGATCTGGGAAACAGCTGCTGTTTTTAATGTGACCAGAGGTTTTGTTCAGAATCTGTTGACTTCAGCTTCGTCGTTTGCCTCATGTATGGTGCATTTCACCCGCGAACTCAATGAATTTTGGGGCCTGAATCTATTGCTGGAGGCAATGGTAAAGAAGCTATCTTTCACCGCAAGTTTGGAACTCATTCCTCTTATGGAAGTCCCTGGTGTGAAGCAGGCTCGTGCTCGTGAGCTATTTAAAGCAGGTTACAAGAGCCTCAGTAGCCTGGCCTGGGCTGATTTAAGTGAGCTGTTGTCCAGGATCGAACATTTATCGAGGCGACAGGCCAATCAGATCGTCTCAGCTGCTAAGATGCTGTTGGAGGAGAAAGCTGACGCTTTAAGGGAAGAGGCAGAAGAATTGTCGTCTATTCCTAAAGAATTACAGAAAATGGATCCAGACGGCTGA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q2VPA6	Helicase POLQ-like OS=Mus musculus OX=10090 GN=Helq PE=1 SV=2
Q8TDG4	Helicase POLQ-like OS=Homo sapiens OX=9606 GN=HELQ PE=1 SV=2
Q9VSE2	Helicase POLQ-like OS=Drosophila melanogaster OX=7227 GN=mus301 PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0002976 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00271 all species →	Helicase_C	Helicase conserved C-terminal domain	Domain	Interproscan
PF20470 all species →	HTH_61	Helix-turn-helix domain	Domain	Interproscan
PF00270 all species →	DEAD	DEAD/DEAH box helicase	Domain	Interproscan
PF21099 all species →	POLQ_helical	DNA_pol_Q helicase like region helical domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR001650 all species →	Domain	Helicase, C-terminal domain-like	Interproscan
IPR014001 all species →	Domain	Helicase superfamily 1/2, ATP-binding domain	Interproscan
IPR050474 all species →	Family	Helicase Hel308/SKI2	Interproscan
IPR046931 all species →	Domain	DNA polymerase theta-like, helix-turn-helix domain	Interproscan
IPR011545 all species →	Domain	DEAD/DEAH box helicase domain	Interproscan
IPR027417 all species →	Homologous_superfamily	P-loop containing nucleoside triphosphate hydrolase	Interproscan
IPR048960 all species →	Domain	POLQ-like, helical domain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR47961 all species →	DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0003676 all species →	Molecular Function	nucleic acid binding	Interproscan
GO:0005524 all species →	Molecular Function	ATP binding	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K19178	HELQ; POLQ-like helicase	EC:5.6.2.4	DNA repair and recombination proteins	ko03400	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of XP_074622293.1 across 84 RNA-seq samples of Acropora palmata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

84Samples

60TPM > 0

2Conditions

17.4Max TPM

7.0Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM	Mean, relative to max
all_coral_tissue · exposed	46	33	6.40	17.36
all_coral_tissue · baseline	38	27	7.79	15.26

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR8800105	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	17.36
SRR8800077	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	13.80
SRR8800068	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	13.33
SRR8800083	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	11.65
SRR8800051	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	11.51
SRR8800071	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	10.97
SRR8800036	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	10.51
SRR8800062	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	10.11
SRR8800097	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	9.95
SRR8800073	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	9.60
SRR8800065	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	9.59
SRR8800099	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	9.42
SRR8800040	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	9.41
SRR8800038	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	9.36
SRR8800053	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	9.12
SRR8800107	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	9.11
SRR8800088	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	8.74
SRR8800093	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	8.65
SRR8800060	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	8.59
SRR8800034	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	8.45
SRR8800089	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	8.25
SRR8800080	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	8.20
SRR8800079	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	6.95
SRR8800063	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	6.95
SRR8800095	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	6.90
SRR8800047	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	6.70
SRR8800026	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	6.40
SRR8800033	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	6.21
SRR8800087	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	6.17
SRR8800044	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	5.99
SRR8800058	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	5.72
SRR8800045	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	5.47
SRR8800027	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	5.30
SRR8800028	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	0.00
SRR8800029	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	0.00
SRR8800039	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	0.00
SRR8800042	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	0.00
SRR8800056	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	0.00
SRR8800061	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	0.00
SRR8800066	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	0.00
SRR8800075	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	0.00
SRR8800086	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	0.00
SRR8800091	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	0.00
SRR8800092	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	0.00
SRR8800094	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	0.00
SRR8800100	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	0.00
SRR8800048	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	15.26
SRR8800101	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	14.61
SRR8800057	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	14.24
SRR8800109	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	13.58
SRR8800035	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	13.45
SRR8800043	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	13.12
SRR8800069	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	12.63
SRR8800072	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	12.43
SRR8800078	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	12.40
SRR8800041	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	12.06
SRR8800067	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	11.99
SRR8800104	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	11.92
SRR8800076	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	11.74
SRR8800074	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	11.17
SRR8800096	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	11.00
SRR8800103	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	10.90
SRR8800090	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	10.47
SRR8800031	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	10.36
SRR8800049	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	9.86
SRR8800037	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	8.93
SRR8800050	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	8.77
SRR8800084	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	8.65
SRR8800102	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	8.30
SRR8800081	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	8.15
SRR8800064	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	7.00
SRR8800085	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	6.77
SRR8800070	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	6.37
SRR8800030	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	0.00
SRR8800032	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	0.00
SRR8800046	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	0.00
SRR8800052	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	0.00
SRR8800054	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	0.00
SRR8800055	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	0.00
SRR8800059	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	0.00
SRR8800082	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	0.00
SRR8800098	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	0.00
SRR8800106	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	0.00
SRR8800108	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	0.00

Source: CnidoSite RNA-seq expression matrices (APALM_TPM, StringTie quantification over 84 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.