Gene detail

Detailed information of XP_074623927.1 in Acropora palmata

Genomic Location: NC_133882.1:13707349...13742029
NR annotation: XP_029211540.1, ras-specific guanine nucleotide-releasing factor 2-like isoform X1 [Acropora millepora]
Species Acropora palmata · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

XP_074623927.1

ATGCCCGCTCCTGTGCGAATTAGTGAAGAACAACTCAAACACCTGGTTTCGTTGGCAAAACACGACTTCTCCATAAGCGGACGTGTTTACATCAAAAACCATGAAAACTCTGGCAAGTGGGTGCAGCGGTGGTGTGCCTTATACCAAAATTTTATGTTTTATTTTGAAAATGAAGATTCTACCAAACTTTCCGGAGCTATTTACTTGGAGCATGCAGTCTGTGAAAGATTATGCTTGACTAACCTAAAGGACAGCGAAAACCAGAATTGCTTCTCAATCAGCACACCAACGGTAGATGGACAGCAACAGTTTATTCTGAGAACAAATACAGATGATGAATGTGTGGCATGGATTGAGGCTATTTCAAACTGCAGTTTTGCTGAGCTGCAATCAGAGAAGGAAGAGTTGAGAAAGAAGTACATCCATGTTATGCAGATATTGGAAAGTGAGAAGACTGCCAAATGGCAATTACTTCAACAGTGTGAGGAGCAAGGGCAGTTGGTGTCTAGCCTCAAAGCTGAGGTTGCAGCTCTTCGAAAGCAAAAGACAGCTGAGGCAAGAGAAGAAGAGAGTGAGGAAATAAGGAACATAAAAAAGGTTCAAAGTCTGATTCGGGGTTGGCTGTGCCGACGTCGCTGGCACAGTATTGTGCAAAATTACATTCGATCGCCACATGCAGAGAGCATGCGTCAGAGAAACTCCCTCTGTTTCCAACTGGTGGAAACTGAAAGTGAATATGTACAAAATCTTTCCACGCTCGTGTCATGTTTCTTCAGACCTCTTAAAATGGCCGCCAGCTCCAAAAAGCCTCCACTAAGTCATGAAGAAGGCAGTTGCATCTTTCTGAATAGCGAAACAATTCTCTTTTTGCATCAAATCTTCCTGAAAGGTCTTCATACCCGCTTGGAAAGCTGGCCGACACTGGTGCTCGGTGACTTGTTTGACATGTTGTTGCCCATGTTAAGCATTTATCAGGAATATGTGAGAAATCATCATTATTCTCTTCAGACGTTAGCTGAATGCAAACAGCGACCCGCTTTCCATCGCCTCTTGAAATTGTACGAGGAAAAACCAGCTTGCAGTGGAAGGACTCTTGAATACTTTCTAACGGCTCCAATGCACAGGGTCCCCGCATATATTATAACTTTGCATGATCTTCTGGCCCTTACTCCTCATAATCACGTGGAAAGGAACACGTTGGAGTATGCGCAGAGCGTTCTTGAAGAACTTTCAACGGTGATGCATGACGAAGTCAGTGAAACTGAGAATATTCGCAAAAATCTATCCATTGAGCGGCAAATTGTGGAAGGTTGCGACATGCTTTTGGATGTTAATCAGATATTTATCCGTCAAGGGAATTTAATTCAGATAACAGAGAGCCGTAAATTCAAGACCTTTGGTGGTCTGTCGCTGAAGCCTTCTGAAGTCAGGAAAGAGACCGTTCGCCAGTGTTTCCTGTTTTCAGGTTACCTGCTTCTAACTTCAAGATCATCCAGCGGTCGCTTGCATCTCTCCAAGAATGGTTCAAACATTTCCCTGGCTGACGCGACACTTGTTGACGATTGTTTTCAAGTGGAGGACGCCGAAAGCATTTTCTATGGCGTGCGAGGAAATCAAGAGCTCGACTTGGATGAGTTGACATTCAAACTGATTGTGCGATCACGTGACAAACCTGATTCAGGATCACCGTACACCGTGACTTTAATGGCGCCTTCACCACAGGAAAAAGCCGAATGGACTTCAGATATCAGTCAGTGCATTGAGAATCTCTCCATGATGGCAGAAGACGATACAGTTTCTGTGTCATCGAGACTAAGTTTGGCGAGTGTCAGATCCGACCCAAAGTTGTTTACTGATGATACAGATATTAAATACTGCAAAGCCTTAAACTGCTGCAAGCTACCTAAGATCCGTCACGCCAGCCTGGAGCGACTACTTGAGCGTCTGTTGGATATTCGCTTTCTCAGTGTTGATTTTCTCAACGCGTTTCTTATCACCTACCGTGTGTTTACCTCAGCTTCAGTACTTCTGGACACACTGTTGGAGTTTTACTATTCCAACAATGCTAAGCAGGCGGATTCCCTTTGCACAGACCTGTTTCCGCCAGTCAACCGTAAAGTCCGATCAGAATCGCTTCCCACATCGTCACTGAGTCCTTTGCCAGACCGGAAGAAAGGTGGCAGTAAGTTCTTTGGTGAGCAGAAGAATTCTTCACCATCTCAGTCCATATCCATCACAGTGTCTGATGTCAAGATGCCGTCAGATAACAACCAAGCGGAAGCTGCTACACCTAGTGAAACTGCTGGGCTCACTCCTGACCGTCTGTGCCCCAGTAACTACCACTCCTATAGGAGGCATTCATCACCCTCGGCTTTGGGCGAGACAGCAGCTTTTGACTTTCCAGAGTCAACTACTGATCAACCACAGTCACCAGGAGAAGATTCACCAGGCCCCATTCGTCACGAGAGCCTTCGAAATCACAGTTCGCCTTTTCTAGCACGTGGCAACATTCGAACCCGAGCCCAGAGCAGCTCGTCAGATTTCGTATCAACAGGAGTCACACACAATAAGCTTAACATGGAAACAAACTCCAAGTTGTCGACGTCACCAGTCGAGGATGTCTTCTGTGACTTGAAATTTGAACTTCAAGCTCCTCCCAAACAACGCCCAAATAGACGCTCCCGTGCTCTTACCCCATCAGGATCCGTCTTGTCCAGTGAAAATCCATCTTCTGGTAGTTCCTCAGTGCATTCCACTGAAGAGAAAACAAAACGGACAACCACAAATACGACTGACAAGGAACTGTCGTTGCAAGATTACGAGAAAGTTAGTCAAAAGACCAAATCCCATCGCCGGAGATCATCTCCCAGCGGATGTCGTGACCGTGGTTCAACGGAGACTCCTCCTGTTAGTTGCTTAGGAATCGTGGCTGATGCTGGCTCACAAACCCCTGAAATATCACGCGAAAAACAATCGAACAAAAGGTCAGGCTCCCCGTGCAAACTTTACAAGATTGTGAAGGATGCAGAAGAGAGGGTGATGAGCTTGAAGTCTCAGCGACGGTCAAGTCCTCCGATGACGACCTCTTATGCGTCGCCCAAATCACCTGTGTCCCCCATCAGCTCACCTAGATCTCCTCTGTCGCCTTCTGCTAACACTGTTAGCGCGGGAGTGGTTGTCACATCATCGATCCCAGCTCGGCGCCGATCCAGTATATCATCTGCAGCCGCGGCATTTGCTGCCGCTACTGCAGGCGCGTCTCCGTCATACGCGGCAACTTCGCCCACTAGATTTCGTTTTGGTCAAAATATCCGTGAATTACTTTCCTCAAACAATCACATGGCCACAATGAGAGTCCTTACCGTTCTTCGACACTGGGTCACAAAACACCCCGAGGACTTTGAGGCTGATCACGCGTTGAAAGAACAGTTAGTGTCGTCAATGAATTACATTTTAAACAGCGATGGTTCCACCAATCTGGAGCAAAAGTTTGCGGCCGCAATTATAAAGACACTTGAGCGGAAACACGAGGAACTAAAAGCGGCTCTTAGCTTTGAGTTAAAGCTGGATCCTGTGAAGACCCCGAAAACCGTGGAGTTGGCAACATTTGATAAGATATCTGCTACACAAATTGCTGAACAACTCACATTCTTGGAGCACTTAATTTTCTCTAAGATTCCTGCACATGAATTTCTCAATCTATCTTGGATGAAATCAGATAAAAATGTACGAGCGCCTAATATTCTACGCGTCACCAAGCGATTCAATGAAACAAGTTCGCTCGTTGCGTCTGAAATCCTTAGGCGCCAGTCTCCCTCAGCTCGCGCGACGGTGATTGAAAAGTGGGCAACTGTTGGTGAAGTTTGTCGGAATCTTCACAATTTTAACTCAGTGTTAGAAATTAGTTCGGCCTTTATGAGCAGTTCCATCTTTCGACTCAAGAAGACGTGGGAAAAGGTGTCAAAACAGACACGGACATTAATTGATCGACTTCAGAAGCTGGTTAGCTCTGATGGTCGCTTTAAAAACATGAGAGAGGCTCTCAGATGTGCGGATCCTCCGTGTGTGCCGTATCTTGGTTTCTACTTGACAGACCTAGCGTTTATTGAAGATGGAACTCCAAACAGTAATGAAAACGGCCTTATTAATTTCTCGAAGATGAGAATGATTGCCCAAGTCATTCAGGAAATCAAGCATTATCAGCAAAATGTATACACACTGGAACATGATAAAAGGATTATACGGTATTTGACTTCCAAAGCGAATCTGATGGATGAGGACATGCTGTATCGTACCTCGCTAACGTTGGAACCCAGAAAACGAGCATCATCGAAATTGAAGCAGCCAGTCGACGCGACCTAG

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
P28818	Ras-specific guanine nucleotide-releasing factor 1 OS=Rattus norvegicus OX=10116 GN=Rasgrf1 PE=1 SV=1
Q13972	Ras-specific guanine nucleotide-releasing factor 1 OS=Homo sapiens OX=9606 GN=RASGRF1 PE=1 SV=2
A2CEA7	Ras-specific guanine nucleotide-releasing factor 2 OS=Danio rerio OX=7955 GN=rasgrf2 PE=3 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0001923 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00617 all species →	RasGEF	RasGEF domain	Family	Interproscan
PF00169 all species →	PH	PH domain	Domain	Interproscan
PF00618 all species →	RasGEF_N	RasGEF N-terminal motif	Domain	Interproscan
PF00621 all species →	RhoGEF	RhoGEF domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR001895 all species →	Domain	Ras guanine-nucleotide exchange factors catalytic domain	Interproscan
IPR001849 all species →	Domain	Pleckstrin homology domain	Interproscan
IPR000219 all species →	Domain	Dbl homology (DH) domain	Interproscan
IPR011993 all species →	Homologous_superfamily	PH-like domain superfamily	Interproscan
IPR035899 all species →	Homologous_superfamily	Dbl homology (DH) domain superfamily	Interproscan
IPR019804 all species →	Conserved_site	Ras guanine-nucleotide exchange factor, conserved site	Interproscan
IPR000048 all species →	Binding_site	IQ motif, EF-hand binding site	Interproscan
IPR000651 all species →	Domain	Ras-like guanine nucleotide exchange factor, N-terminal	Interproscan
IPR023578 all species →	Homologous_superfamily	Ras guanine nucleotide exchange factor domain superfamily	Interproscan
IPR036964 all species →	Homologous_superfamily	Ras guanine-nucleotide exchange factor, catalytic domain superfamily	Interproscan
IPR008937 all species →	Family	Ras-like guanine nucleotide exchange factor	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR23113 all species →	GUANINE NUCLEOTIDE EXCHANGE FACTOR	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005085 all species →	Molecular Function	guanyl-nucleotide exchange factor activity	Interproscan
GO:0007264 all species →	Biological Process	small GTPase-mediated signal transduction	Interproscan
GO:0005515 all species →	Molecular Function	protein binding	Interproscan
GO:0005886 all species →	Cellular Component	plasma membrane	Interproscan
GO:0007265 all species →	Biological Process	Ras protein signal transduction	Interproscan
GO:0043547 all species →	Biological Process	positive regulation of GTPase activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K04349	RASGRF1; Ras-specific guanine nucleotide-releasing factor 1	-	Focal adhesion	ko04510	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of XP_074623927.1 across 84 RNA-seq samples of Acropora palmata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

84Samples

51TPM > 0

2Conditions

21.1Max TPM

4.4Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM	Mean, relative to max
all_coral_tissue · exposed	46	29	4.31	21.07
all_coral_tissue · baseline	38	22	4.59	13.00

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR8800034	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	21.07
SRR8800033	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	14.15
SRR8800073	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	14.07
SRR8800042	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	13.08
SRR8800068	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	10.16
SRR8800036	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	8.68
SRR8800077	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	8.49
SRR8800100	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	8.31
SRR8800051	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	8.06
SRR8800071	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	7.89
SRR8800097	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	7.57
SRR8800044	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	7.02
SRR8800080	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	6.96
SRR8800053	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	6.81
SRR8800099	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	6.56
SRR8800083	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	6.08
SRR8800045	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	6.05
SRR8800079	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	5.47
SRR8800038	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	5.14
SRR8800093	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	5.08
SRR8800040	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	3.26
SRR8800058	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	2.90
SRR8800063	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	2.68
SRR8800087	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	2.60
SRR8800107	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	2.30
SRR8800095	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	2.22
SRR8800062	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	1.89
SRR8800060	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	1.84
SRR8800065	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	1.72
SRR8800026	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	0.00
SRR8800027	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	0.00
SRR8800028	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	0.00
SRR8800029	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	0.00
SRR8800039	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	0.00
SRR8800047	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	0.00
SRR8800056	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	0.00
SRR8800061	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	0.00
SRR8800066	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	0.00
SRR8800075	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	0.00
SRR8800086	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	0.00
SRR8800088	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	0.00
SRR8800089	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	0.00
SRR8800091	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	0.00
SRR8800092	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	0.00
SRR8800094	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	0.00
SRR8800105	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781	0.00
SRR8800106	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	13.00
SRR8800069	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	11.08
SRR8800057	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	10.34
SRR8800067	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	10.33
SRR8800041	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	10.13
SRR8800043	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	9.78
SRR8800072	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	9.69
SRR8800048	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	9.36
SRR8800096	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	9.19
SRR8800037	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	8.80
SRR8800074	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	8.58
SRR8800078	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	8.56
SRR8800050	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	8.49
SRR8800081	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	7.91
SRR8800101	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	7.07
SRR8800076	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	6.65
SRR8800049	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	6.43
SRR8800109	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	6.03
SRR8800103	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	4.29
SRR8800102	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	3.81
SRR8800070	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	3.23
SRR8800085	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	1.57
SRR8800030	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	0.00
SRR8800031	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	0.00
SRR8800032	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	0.00
SRR8800035	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	0.00
SRR8800046	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	0.00
SRR8800052	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	0.00
SRR8800054	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	0.00
SRR8800055	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	0.00
SRR8800059	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	0.00
SRR8800064	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	0.00
SRR8800082	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	0.00
SRR8800084	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	0.00
SRR8800090	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	0.00
SRR8800098	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	0.00
SRR8800104	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	0.00
SRR8800108	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781	0.00

Source: CnidoSite RNA-seq expression matrices (APALM_TPM, StringTie quantification over 84 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.