Genomic Location: NC_133882.1:28626319...28656326
NR annotation: XP_044175601.1, A disintegrin and metalloproteinase with thrombospondin motifs 6-like [Acropora millepora]
Species Acropora palmata · all data for this species · gene families
| CDS |
| XP_074624323.1 |
| Protein |
| XP_074624323.1 |
| UniProt accession | Description |
|---|---|
| Q8TE57 | A disintegrin and metalloproteinase with thrombospondin motifs 16 OS=Homo sapiens OX=9606 GN=ADAMTS16 PE=1 SV=3 |
| Q69Z28 | A disintegrin and metalloproteinase with thrombospondin motifs 16 OS=Mus musculus OX=10090 GN=Adamts16 PE=2 SV=2 |
| Q9UKP5 | A disintegrin and metalloproteinase with thrombospondin motifs 6 OS=Homo sapiens OX=9606 GN=ADAMTS6 PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0000429 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF01421 all species → | Reprolysin | Reprolysin (M12B) family zinc metalloprotease | Domain | Interproscan |
| PF01562 all species → | Pep_M12B_propep | Reprolysin family propeptide | Family | Interproscan |
| PF19030 all species → | TSP1_ADAMTS | Thrombospondin type 1 domain | Domain | Interproscan |
| PF00090 all species → | TSP_1 | Thrombospondin type 1 domain | Domain | Interproscan |
| PF00431 all species → | CUB | CUB domain | Domain | Interproscan |
| PF19236 all species → | ADAMTS_CR_3 | ADAMTS cysteine-rich domain | Domain | Interproscan |
| PF17771 all species → | ADAMTS_CR_2 | ADAMTS cysteine-rich domain 2 | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR024079 all species → | Homologous_superfamily | Metallopeptidase, catalytic domain superfamily | Interproscan |
| IPR000859 all species → | Domain | CUB domain | Interproscan |
| IPR036383 all species → | Homologous_superfamily | Thrombospondin type-1 (TSP1) repeat superfamily | Interproscan |
| IPR000884 all species → | Repeat | Thrombospondin type-1 (TSP1) repeat | Interproscan |
| IPR001590 all species → | Domain | Peptidase M12B, ADAM/reprolysin | Interproscan |
| IPR035914 all species → | Homologous_superfamily | Spermadhesin, CUB domain superfamily | Interproscan |
| IPR013273 all species → | Family | ADAMTS/ADAMTS-like | Interproscan |
| IPR050439 all species → | Family | ADAMTS and ADAMTS-like | Interproscan |
| IPR002870 all species → | Domain | Peptidase M12B, propeptide | Interproscan |
| IPR045371 all species → | Domain | ADAMTS/ADAMTS-like, cysteine-rich domain 3 | Interproscan |
| IPR041645 all species → | Domain | ADAMTS, cysteine-rich domain 2 | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR13723 all species → | ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0008237 all species → | Molecular Function | metallopeptidase activity | Interproscan |
| GO:0004222 all species → | Molecular Function | metalloendopeptidase activity | Interproscan |
| GO:0006508 all species → | Biological Process | proteolysis | Interproscan |
| GO:0030198 all species → | Biological Process | extracellular matrix organization | Interproscan |
| GO:0031012 all species → | Cellular Component | extracellular matrix | Interproscan |
XP_074624323.1.Transcript abundance of XP_074624323.1 across 84 RNA-seq samples of Acropora palmata. This gene has no row in the species' RNA-seq expression matrix, so every value below is shown as zero — the matrix simply does not cover this transcript. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| all_coral_tissue · exposed | 46 | 0 | 0.00 | 0.00 | |
| all_coral_tissue · baseline | 38 | 0 | 0.00 | 0.00 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| SRR8800026 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800027 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800028 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800029 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800033 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800034 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800036 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800038 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800039 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800040 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800042 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800044 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800045 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800047 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800051 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800053 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800056 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800058 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800060 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800061 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800062 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800063 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800065 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800066 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800068 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800071 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800073 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800075 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800077 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800079 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800080 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800083 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800086 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800087 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800088 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800089 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800091 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800092 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800093 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800094 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800095 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800097 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800099 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800100 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800105 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800107 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800030 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800031 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800032 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800035 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800037 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800041 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800043 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800046 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800048 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800049 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800050 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800052 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800054 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800055 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800057 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800059 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800064 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800067 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800069 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800070 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800072 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800074 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800076 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800078 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800081 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800082 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800084 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800085 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800090 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800096 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800098 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800101 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800102 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800103 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800104 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800106 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800108 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800109 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
Source: CnidoSite RNA-seq expression matrices (APALM_TPM,
StringTie quantification over 84 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
Genes whose expression across the transcriptome samples of Acropora palmata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
| Direction | Partners | Most correlated partner | PCC |
|---|---|---|---|
| Positively correlated | 0 | not in this network | - |
| Negatively correlated | 0 | not in this network | - |
This gene has no edge at all in the Acropora palmata network, in either direction — it is not one of the genes the network was built from (the network covers genes with enough expression variation across the transcriptome samples). The counts above are a property of the network, not a failed lookup.
Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.
Whether this gene can be visualised in the single-cell atlases of Acropora palmata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
| Sample | Methylation profile |
|---|---|
| Polyp_Underside_Control_2 | open |
| Polyp_Underside_Control_3 | open |
| Polyp_Underside_Treatment_1 | open |
| Polyp_Upperside_Control_1 | open |
| Polyp_Upperside_Treatment_3 | open |
| Polyp_Upperside_Treatment_4 | open |
The DNA Methylation page locates this gene by scanning the bisulphite table, which holds one row per cytosine. For the largest datasets that scan takes a while to return; it does not mean the link is broken.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
