Detailed information of XP_074624820.1 in Acropora palmata

Genomic Location: NC_133887.1:9492425...9504789
NR annotation: XP_029212874.2, LOW QUALITY PROTEIN: 6-phosphogluconate dehydrogenase, decarboxylating-like [Acropora millepora]
Species Acropora palmata · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
P522096-phosphogluconate dehydrogenase, decarboxylating OS=Homo sapiens OX=9606 GN=PGD PE=1 SV=3
Q9DCD06-phosphogluconate dehydrogenase, decarboxylating OS=Mus musculus OX=10090 GN=Pgd PE=1 SV=3
P003496-phosphogluconate dehydrogenase, decarboxylating OS=Ovis aries OX=9940 GN=PGD PE=1 SV=4
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0004556 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF03446
all species →		NAD_binding_2NAD binding domain of 6-phosphogluconate dehydrogenaseDomainInterproscan
PF00393
all species →		6PGD6-phosphogluconate dehydrogenase, C-terminal domainDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR006183
all species →		Family6-phosphogluconate dehydrogenaseInterproscan
IPR006114
all species →		Domain6-phosphogluconate dehydrogenase, C-terminalInterproscan
IPR013328
all species →		Homologous_superfamily6-phosphogluconate dehydrogenase, domain 2Interproscan
IPR006115
all species →		Domain6-phosphogluconate dehydrogenase, NADP-bindingInterproscan
IPR006184
all species →		Binding_site6-phosphogluconate-binding siteInterproscan
IPR036291
all species →		Homologous_superfamilyNAD(P)-binding domain superfamilyInterproscan
IPR006113
all species →		Family6-phosphogluconate dehydrogenase, decarboxylatingInterproscan
IPR008927
all species →		Homologous_superfamily6-phosphogluconate dehydrogenase-like, C-terminal domain superfamilyInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR11811
all species →		6-PHOSPHOGLUCONATE DEHYDROGENASEInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0004616
all species →		Molecular Functionphosphogluconate dehydrogenase (decarboxylating) activityInterproscan
GO:0006098
all species →		Biological Processpentose-phosphate shuntInterproscan
GO:0050661
all species →		Molecular FunctionNADP bindingInterproscan
GO:0005829
all species →		Cellular ComponentcytosolInterproscan
GO:0009051
all species →		Biological Processpentose-phosphate shunt, oxidative branchInterproscan
GO:0046177
all species →		Biological ProcessD-gluconate catabolic processInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K00033PGD, gnd, gntZ; 6-phosphogluconate dehydrogenaseEC:1.1.1.44
EC:1.1.1.343
Glutathione metabolismko00480deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of XP_074624820.1 across 84 RNA-seq samples of Acropora palmata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

84Samples
83TPM > 0
2Conditions
546.6Max TPM
284.5Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
all_coral_tissue · exposed 46 46 303.89 546.59
all_coral_tissue · baseline 38 37 261.13 460.03

Per sample · hover a bar for the full sample record

Show the sample table (84 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
SRR8800066 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 546.59
SRR8800045 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 506.09
SRR8800079 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 505.83
SRR8800075 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 426.38
SRR8800042 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 421.91
SRR8800086 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 399.67
SRR8800033 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 382.99
SRR8800092 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 372.21
SRR8800068 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 372.00
SRR8800053 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 363.52
SRR8800083 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 358.79
SRR8800088 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 357.93
SRR8800071 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 357.47
SRR8800080 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 349.01
SRR8800058 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 345.38
SRR8800044 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 344.74
SRR8800093 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 335.72
SRR8800105 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 335.44
SRR8800099 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 331.88
SRR8800051 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 321.89
SRR8800034 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 317.51
SRR8800056 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 316.37
SRR8800036 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 315.28
SRR8800089 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 305.47
SRR8800087 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 304.49
SRR8800100 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 297.62
SRR8800040 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 295.00
SRR8800039 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 277.68
SRR8800097 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 269.10
SRR8800095 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 252.41
SRR8800077 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 250.81
SRR8800028 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 247.94
SRR8800062 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 245.43
SRR8800107 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 244.74
SRR8800063 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 241.54
SRR8800065 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 234.21
SRR8800038 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 218.91
SRR8800060 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 215.43
SRR8800061 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 206.07
SRR8800094 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 192.03
SRR8800091 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 187.97
SRR8800047 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 185.28
SRR8800073 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 178.12
SRR8800027 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 156.37
SRR8800026 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 153.68
SRR8800029 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 134.20
SRR8800052 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 460.03
SRR8800082 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 367.00
SRR8800081 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 357.95
SRR8800050 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 355.69
SRR8800049 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 339.53
SRR8800037 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 339.01
SRR8800101 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 338.28
SRR8800108 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 319.45
SRR8800074 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 290.82
SRR8800090 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 289.02
SRR8800048 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 285.47
SRR8800054 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 283.35
SRR8800067 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 282.53
SRR8800041 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 279.72
SRR8800064 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 277.45
SRR8800072 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 270.37
SRR8800096 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 270.37
SRR8800069 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 268.89
SRR8800035 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 268.21
SRR8800032 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 261.44
SRR8800057 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 251.90
SRR8800043 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 250.10
SRR8800059 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 249.24
SRR8800106 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 245.90
SRR8800076 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 245.55
SRR8800085 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 240.74
SRR8800055 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 232.51
SRR8800109 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 226.37
SRR8800070 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 217.10
SRR8800098 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 212.09
SRR8800103 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 210.28
SRR8800078 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 206.52
SRR8800031 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 202.88
SRR8800102 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 197.72
SRR8800084 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 189.18
SRR8800104 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 184.46
SRR8800030 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 155.95
SRR8800046 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 0.00

Source: CnidoSite RNA-seq expression matrices (APALM_TPM, StringTie quantification over 84 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Acropora palmata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated1XP_074619184.10.701837136625727
Negatively correlated47XP_074631918.1-0.617481514423295

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Acropora palmata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

DNA methylation (bisulphite samples)

SampleMethylation profile
Polyp_Underside_Control_2open
Polyp_Underside_Control_3open
Polyp_Underside_Treatment_1open
Polyp_Upperside_Control_1open
Polyp_Upperside_Treatment_3open
Polyp_Upperside_Treatment_4open

The DNA Methylation page locates this gene by scanning the bisulphite table, which holds one row per cytosine. For the largest datasets that scan takes a while to return; it does not mean the link is broken.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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