Gene detail

Detailed information of XP_074630294.1 in Acropora palmata

Genomic Location: NC_133889.1:1065772...1081350
NR annotation: XP_029189548.2, crossover junction endonuclease MUS81-like isoform X1 [Acropora millepora]
Species abbreviation APALM · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

XP_074630294.1

ATGACAGAAACAAACTGTAAGAACGCTCGGCTCGAAAAAAAAATGCCTTCAAATCGCCGTAAGAAACAGCGAGAATGCCCCAACCCTCTTTTCTTAAAATGGTTGGAACAGTGGAGGGATGAGGCGAAACAAAAGAACTCGAAGCTGCAGTACACCTATGGAAAGGCTGCTGCTGCTTTGAGGAAATATCCTTTACCCTTGAGCTGCGGCAAAGAGGCAATGATACTTGATAATATTGGTGACATGATTGCTAGGCAGTTGGATGAAGCCATGGAAAAGCATAATGCCTGTAACCTAGAGTCTGAAGTTTTAGAGGTTGACTGTATTGAGGAGGACTATGAAGACAGGAGAGAAAGAGATTCCACACTTGCATCCCTGAATGTTCCTTCTCCACCTCAAATGCTGGACTTGGACCCTGATGTTGAAATGCATGCGATAACTAAGAAAAAGCCCCCAAGGAGAAAAAGTATTCGTGAATATATCCCAGCCTTTAGATCAGGACCCTTTGCTCTGATGTTAACATTGTACAGAGAGAGTCGGAAAGTCAACTATCGCGGATACATGACCCGCCCAGAGCTGCAAAAGGAAGCCCAACCACTCTGCGATGCTTCATTCACTGTGCCTGATCCAGGTAGTCATTACACAGCTTGGTCTTCGATGTCCACTTTGACAAAGAAAGGATTGATTCTCAAGACCAATAACCCTGCGAGTGTTGGCTTGCAAAGGATCTTCTCAGCTACGTCCCGAAACATTTCCTTCTTTAATATTTCTTACCTTAGGTATTCTCTGACGGGTGCAGGCATCGCATTGGCTGGGAAGCTTGAAGGTGTTACGGAAACTGATAGTTTAACATCAATATCCATGACCACAGACACAAGACTTCAATTTCCACCAAACTGCAGTGACAGGAAAACCACTTGCAGAACTTATGACACATCTAGCAACACAAATATAGAACAGGATGAATTTATATGTATAGAAGTGACAGAACCACAATGCTCCGATAAACAAATGACAACAGGAAATTCCCGTAATTTTACCGAGGTTAAAAAGAGGGAACAAAAAGGTGAAGTTGAGAAAGTAATAAGAATTGAGGAAGATGATGTAAGTGCCACCCCAGATATCGTCCTAAGACCAGGTACTTTTGATATTGTTTTGTGTGTTGACGTCAATGAGACCTCAACAGGACAAGCCAAATCAAGGAAGGATGCACTGGCGCCCGAACTGAAGAAAAATGGAGTGCAATTTGATGTCCGTAAACTTCAACTTGGTGATTTTCTTTGGGTAGCACGAGAACGAACCATTCCCACACCAGGTTGTTTGTCAGTGCCAGTTCCTCGTGAATTAGTGTTGGATTATATCGTTGAGAGAAAAAGAATGGATGACTTATGTGGCAGTATTATCGATGGCCGATTCAGGGAGCAGAAGTTTCGCTTGCACCATTGTGGTCTGAAACATCCAATCTACCTTGTGGAGGATTTCGGTTCCATTCAACACATGAGCCTTCCAGAAAGCACTCTGCAACAAGCTATTGTCAACACTCAGGTTGTTGATGGTTTCTTTGTGAAGCGAACACACGATTTAAAGGAGTCCGTTGCATATTTGACAGTGATGACCCGATACCTACAAAGAATTTACTCGAATAAGACTCTTTTAAGTTGGTGTCAAAAGCGCCAGGAAGAGGAAAGAGCATTCACAAAAAGACAAGCAGATAGAGTCTATCTCATTAACTTCCCGGACTTTAATGACTCAACTGTGAAAAATAAGGTGATGACAGTTAGTGAGGTTTTCGCCAAGCAGCTCATGCAGATAAACGGAATGTCGTCAGACAAAGCTGTTGCTATTATTGAGAAACACCCTACTCCTAAAAGGCTTGTTGATGCGTACAGATCACTCATCAATTTGAAAGAGAGGGAATTGCTTCTCTCTGTACTCAAGTGCGGCAAAAACCAAAGAAACCTGGGTCCAACTCTTAGCAGACTGATTCACACACTGTATAGCTCACCTACTCTATCTTAA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q640B4	Structure-specific endonuclease subunit MUS81 OS=Xenopus tropicalis OX=8364 GN=mus81 PE=2 SV=1
Q7SXA9	Structure-specific endonuclease subunit MUS81 OS=Danio rerio OX=7955 GN=mus81 PE=1 SV=1
Q96NY9	Structure-specific endonuclease subunit MUS81 OS=Homo sapiens OX=9606 GN=MUS81 PE=1 SV=3

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0003681 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF02732 all species →	ERCC4	ERCC4 domain	Domain	Interproscan
PF21136 all species →	MUS81-like_WH	Crossover junction endonuclease MUS81-like, winged helix domain	Domain	Interproscan
PF21292 all species →	EME1-MUS81_C	EME1/MUS81, C-terminal	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR006166 all species →	Domain	ERCC4 domain	Interproscan
IPR027421 all species →	Homologous_superfamily	DNA polymerase lambda lyase domain superfamily	Interproscan
IPR042530 all species →	Homologous_superfamily	EME1/EME2, C-terminal domain	Interproscan
IPR047416 all species →	Domain	MUS81, XPF-like nuclease domain	Interproscan
IPR033309 all species →	Family	Crossover junction endonuclease Mus81	Interproscan
IPR047417 all species →	Domain	MUS81, winged helix domain	Interproscan
IPR036388 all species →	Homologous_superfamily	Winged helix-like DNA-binding domain superfamily	Interproscan
IPR011335 all species →	Homologous_superfamily	Restriction endonuclease type II-like	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR13451 all species →	CLASS II CROSSOVER JUNCTION ENDONUCLEASE MUS81	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0003677 all species →	Molecular Function	DNA binding	Interproscan
GO:0004518 all species →	Molecular Function	nuclease activity	Interproscan
GO:0000712 all species →	Biological Process	resolution of meiotic recombination intermediates	Interproscan
GO:0000727 all species →	Biological Process	double-strand break repair via break-induced replication	Interproscan
GO:0005634 all species →	Cellular Component	nucleus	Interproscan
GO:0006302 all species →	Biological Process	double-strand break repair	Interproscan
GO:0006308 all species →	Biological Process	DNA catabolic process	Interproscan
GO:0008821 all species →	Molecular Function	crossover junction DNA endonuclease activity	Interproscan
GO:0031573 all species →	Biological Process	mitotic intra-S DNA damage checkpoint signaling	Interproscan
GO:0048257 all species →	Molecular Function	3'-flap endonuclease activity	Interproscan
GO:0048476 all species →	Cellular Component	Holliday junction resolvase complex	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K08991	MUS81; crossover junction endonuclease MUS81	EC:3.1.22.-	DNA repair and recombination proteins	ko03400	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.