Detailed information of XP_074632640.1 in Acropora palmata

Genomic Location: NC_133890.1:18173596...18188985
NR annotation: XP_029186125.2, calpain-5-like [Acropora millepora]
Species Acropora palmata · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
O15484Calpain-5 OS=Homo sapiens OX=9606 GN=CAPN5 PE=1 SV=2
O08688Calpain-5 OS=Mus musculus OX=10090 GN=Capn5 PE=1 SV=1
Q8R4C0Calpain-5 OS=Rattus norvegicus OX=10116 GN=Capn5 PE=1 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0000855 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF01067
all species →		Calpain_IIICalpain large subunit, domain IIIDomainInterproscan
PF00168
all species →		C2C2 domainDomainInterproscan
PF00648
all species →		Peptidase_C2Calpain family cysteine proteaseFamilyInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR033883
all species →		DomainCalpain subdomain IIIInterproscan
IPR000008
all species →		DomainC2 domainInterproscan
IPR022682
all species →		DomainPeptidase C2, calpain, large subunit, domain IIIInterproscan
IPR000169
all species →		Active_siteCysteine peptidase, cysteine active siteInterproscan
IPR050420
all species →		FamilyCalpainInterproscan
IPR022683
all species →		DomainPeptidase C2, calpain, domain IIIInterproscan
IPR001300
all species →		DomainPeptidase C2, calpain, catalytic domainInterproscan
IPR035892
all species →		Homologous_superfamilyC2 domain superfamilyInterproscan
IPR038765
all species →		Homologous_superfamilyPapain-like cysteine peptidase superfamilyInterproscan
IPR033884
all species →		DomainCalpain C2 domainInterproscan
IPR022684
all species →		FamilyPeptidase C2, calpain familyInterproscan
IPR036213
all species →		Homologous_superfamilyCalpain large subunit, domain III superfamilyInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR10183
all species →		CALPAINInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0004198
all species →		Molecular Functioncalcium-dependent cysteine-type endopeptidase activityInterproscan
GO:0005737
all species →		Cellular ComponentcytoplasmInterproscan
GO:0006508
all species →		Biological ProcessproteolysisInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K08574CAPN5; calpain-5EC:3.4.22.-
Peptidases and inhibitorsko01002deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of XP_074632640.1 across 84 RNA-seq samples of Acropora palmata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

84Samples
84TPM > 0
2Conditions
149.7Max TPM
50.3Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
all_coral_tissue · exposed 46 46 57.50 149.68
all_coral_tissue · baseline 38 38 41.57 80.16

Per sample · hover a bar for the full sample record

Show the sample table (84 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
SRR8800034 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 149.68
SRR8800073 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 131.01
SRR8800039 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 93.48
SRR8800086 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 92.07
SRR8800066 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 79.20
SRR8800075 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 78.69
SRR8800033 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 78.28
SRR8800028 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 76.85
SRR8800092 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 72.85
SRR8800087 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 72.13
SRR8800042 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 65.22
SRR8800088 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 61.92
SRR8800107 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 60.94
SRR8800095 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 59.90
SRR8800047 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 59.36
SRR8800080 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 55.90
SRR8800099 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 55.65
SRR8800068 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 55.64
SRR8800056 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 55.06
SRR8800077 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 54.91
SRR8800036 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 54.63
SRR8800105 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 53.84
SRR8800053 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 53.54
SRR8800097 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 50.98
SRR8800079 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 49.67
SRR8800093 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 49.24
SRR8800065 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 49.11
SRR8800071 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 48.21
SRR8800083 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 47.12
SRR8800100 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 46.96
SRR8800062 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 46.80
SRR8800040 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 46.15
SRR8800044 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 45.82
SRR8800051 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 45.36
SRR8800058 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 41.38
SRR8800063 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 40.99
SRR8800045 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 40.80
SRR8800089 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 40.78
SRR8800038 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 40.51
SRR8800060 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 39.47
SRR8800061 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 38.87
SRR8800027 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 36.61
SRR8800029 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 34.35
SRR8800091 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 33.63
SRR8800026 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 32.86
SRR8800094 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 28.40
SRR8800046 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 80.16
SRR8800052 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 69.76
SRR8800102 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 48.97
SRR8800069 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 48.61
SRR8800101 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 47.98
SRR8800108 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 47.37
SRR8800032 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 47.09
SRR8800085 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 46.50
SRR8800043 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 45.62
SRR8800074 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 45.35
SRR8800064 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 44.95
SRR8800067 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 44.34
SRR8800096 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 44.10
SRR8800035 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 43.54
SRR8800103 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 42.67
SRR8800109 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 40.87
SRR8800048 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 40.62
SRR8800041 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 40.62
SRR8800057 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 40.37
SRR8800049 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 40.28
SRR8800072 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 40.10
SRR8800070 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 39.28
SRR8800081 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 38.81
SRR8800050 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 38.79
SRR8800037 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 38.70
SRR8800098 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 37.53
SRR8800084 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 37.22
SRR8800082 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 37.06
SRR8800104 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 36.49
SRR8800078 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 35.54
SRR8800054 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 34.15
SRR8800076 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 33.71
SRR8800059 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 33.56
SRR8800055 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 33.28
SRR8800090 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 33.11
SRR8800030 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 32.55
SRR8800031 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 25.41
SRR8800106 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 24.73

Source: CnidoSite RNA-seq expression matrices (APALM_TPM, StringTie quantification over 84 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Acropora palmata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated17XP_074615715.10.821787635950688
Negatively correlated44XP_074624663.1-0.553173072454193

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Acropora palmata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

DNA methylation (bisulphite samples)

SampleMethylation profile
Polyp_Underside_Control_2open
Polyp_Underside_Control_3open
Polyp_Underside_Treatment_1open
Polyp_Upperside_Control_1open
Polyp_Upperside_Treatment_3open
Polyp_Upperside_Treatment_4open

The DNA Methylation page locates this gene by scanning the bisulphite table, which holds one row per cytosine. For the largest datasets that scan takes a while to return; it does not mean the link is broken.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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