Gene detail

Detailed information of XP_074634722.1 in Acropora palmata

Genomic Location: NC_133882.1:1148758...1156659
NR annotation: XP_015770888.1, PREDICTED: potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4-like [Acropora digitifera]
Species Acropora palmata · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

XP_074634722.1

ATGCAACGACTTCAGACTTTTGATGATGAGAACGCTCAAGGTTATGACCAGATACACAAGAATGTCCTAGGAGCAGATTTCAAGGAAAGGAAAACGCCAGATTCTGCTGAAGTGGAAGTGCTTCGTGATTTCGATCCGATTTGCACCAAGCCTTTTTTAAATGGCAATAGCAGGGCTCCAGTTAGTGAAGAAGACATTTTTGTTGAGAAACCGCGGGAAGTCATGTCAGCGAGACACAGCAACCTATCGACGAGAATTGGTAGAAGGGTGCGTTCATTTTTCGATACAAGGAGACCTCGGTCGCATACAGCACAGGTGCAGTTCAGCAAGGCCAATGGCGTCAATGTAGTAATTACAATTGAGGATGAAGCAAAGTGTACACCTAGGTCAGACACATCTTTCCGTCGCTTTAAAGAGTGGCTCCAACCCATGGACAATAAGTTAAACATAAAAGTCTTCGGAAGTCGAAAAGCGATGGATGAAGAAATGCTACGTTACAAGACAGCTGGTTGGATAATACACCCTTTGAGCGCTTTCAGGCTTTACTGGGACCTGATCATTCTAGCTTTGTTGATTGTGAACATGTTTGTGTTACCATTAGCCATTGCTTTCTTCATTGACGATATGAGTTCAAAATGGGTCGCTGTGAATCTTGCTTCTGACGGGATTTTGTTGCTCGATATAGTATTGAACTTTAAAACTGGTGTGCTGGTTCATGGTACTCCAAATATATTTATTCTAGACCCCAAGAAAATTGCGATGCGGTACGCGAGAGGATGGTTTATGATCGATCTCATATCATCCTTTCCGTTTGATTACGTTGTATCGTCCGCTTCTAGCCTTCACTCGCAGGGTCGTCTGTTTGGTGCCTCACGGGCCCTTCGCATTCTGCGCATGGCAAAACTGCTTAGTTTACTGCGTCTTCTCAGGATATCTCGTCTGGTTCGCAAAGTTTATCAGTACGAGGAGGTTCTTAACATAACCCGTTCAGTTATTCGGTTTTTTAACTTGGTAAGCCTAATGTTGTTGGTGGCTCACTGGAATGGCTGCATGCAGTTTCTAGTCCCAGTTCTCGACGATTTCCCTGACGATTCTTGGGTCATGCTCCATAACTTGCGGTATAAGCCATGGACGGAGCAGTATTTCTGGGCATTGTTCAAAGCCCTGTCACATATGTTATGTATTGGTTACGGAAGGCATCCACCCCAGAACATTCCTGAGACTTGCGTCACTATATCCAGTATGATGACGGGAGCAACATTCTATGCTCTCTTCATTGCTTATTCCATCAATGTCATCCAGACCATGGACTCGCCGGGTCGCAGTTACAAGGAGAAGATTAAAGAGATCGAGGAATATATGTCTCATAGACGGCTGCCTGTTTCTCTTCGGGACAAAATTACCAAATATTACGAGCACCGTTTTCGGGGAAAGCTGTTTGACGAGGAAAGATTGCTGCGTGAAGTGTCTAGACCTCTTCGAACGTCAATTGTCAATTACAATTGCCGCGAACTGGTGCGTAAAGTGCCATTTTTCTCCGATGCCGATCCAGAGTTCGTGTCCGCTATAATAACCAAACTGGAGTTTGAAGTTTACTTGGAGGACGATATTATCATTCGCGAGGGGCAAATGGGTACAGAGATGTACTTTCTCAAATCTGGCGTTGTAAGTGTAAGCTGTGAGGGCAAAGTCAGCGATGATTTGACTGATGGGGCATATTTCGGAGAAATTTGCTTGTTGACAAATGCCCGTCGTACGGCTACCATTGTCGCCAAGAGTGTATGTGACATTTACATTCTGCACGCGGATGATTTTAGAGAGGTAGTAGATGAGTATCCAGAGATGCGACAACTCATGGAATCGGTAGCGACCAGGCGACTGAGTAAAATGGGAAAATCAGTGGATCTTATGACGTATCAGTCAAAAGACTATGCGGCTACGAACCTGCAAAGCTCCATCGATGGTAGCGTACTATGTGGCAGCTGCTCTAACTTAATACAAATGCCGGAAAATCCTGTTCACCCGCATATTGTAATTACAAGGGTCGACTCAAATGAAGATCTTACCGACGACTACTTGATCACATAG

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
O88703	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 OS=Mus musculus OX=10090 GN=Hcn2 PE=1 SV=1
Q9JKA9	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 OS=Rattus norvegicus OX=10116 GN=Hcn2 PE=1 SV=4
Q9TV66	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 OS=Oryctolagus cuniculus OX=9986 GN=HCN4 PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0001631 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF08412 all species →	Ion_trans_N	Ion transport protein N-terminal	Family	Interproscan
PF00520 all species →	Ion_trans	Ion transport protein	Family	Interproscan
PF00027 all species →	cNMP_binding	Cyclic nucleotide-binding domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR018488 all species →	Conserved_site	Cyclic nucleotide-binding, conserved site	Interproscan
IPR014710 all species →	Homologous_superfamily	RmlC-like jelly roll fold	Interproscan
IPR018490 all species →	Homologous_superfamily	Cyclic nucleotide-binding domain superfamily	Interproscan
IPR051413 all species →	Family	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel	Interproscan
IPR013621 all species →	Domain	Ion transport N-terminal	Interproscan
IPR000595 all species →	Domain	Cyclic nucleotide-binding domain	Interproscan
IPR005821 all species →	Domain	Ion transport domain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR45689 all species →	I[[H]] CHANNEL, ISOFORM E	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0003254 all species →	Biological Process	regulation of membrane depolarization	Interproscan
GO:0005249 all species →	Molecular Function	voltage-gated potassium channel activity	Interproscan
GO:0035725 all species →	Biological Process	sodium ion transmembrane transport	Interproscan
GO:0071805 all species →	Biological Process	potassium ion transmembrane transport	Interproscan
GO:0098855 all species →	Cellular Component	HCN channel complex	Interproscan
GO:0005216 all species →	Molecular Function	monoatomic ion channel activity	Interproscan
GO:0006811 all species →	Biological Process	monoatomic ion transport	Interproscan
GO:0016020 all species →	Cellular Component	membrane	Interproscan
GO:0055085 all species →	Biological Process	transmembrane transport	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K04955	HCN2; hyperpolarization activated cyclic nucleotide-gated potassium channel 2	-	Ion channels	ko04040	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of XP_074634722.1 across 84 RNA-seq samples of Acropora palmata. This gene has no row in the species' RNA-seq expression matrix, so every value below is shown as zero — the matrix simply does not cover this transcript. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

84Samples

0TPM > 0

2Conditions

0.0Max TPM

0.0Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM	Mean, relative to max
all_coral_tissue · exposed	46	0	0.00	0.00
all_coral_tissue · baseline	38	0	0.00	0.00

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study
SRR8800026	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800027	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800028	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800029	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800033	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800034	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800036	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800038	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800039	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800040	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800042	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800044	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800045	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800047	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800051	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800053	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800056	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800058	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800060	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800061	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800062	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800063	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800065	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800066	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800068	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800071	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800073	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800075	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800077	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800079	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800080	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800083	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800086	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800087	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800088	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800089	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800091	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800092	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800093	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800094	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800095	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800097	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800099	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800100	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800105	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800107	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800030	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800031	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800032	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800035	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800037	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800041	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800043	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800046	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800048	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800049	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800050	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800052	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800054	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800055	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800057	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800059	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800064	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800067	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800069	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800070	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800072	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800074	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800076	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800078	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800081	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800082	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800084	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800085	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800090	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800096	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800098	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800101	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800102	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800103	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800104	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800106	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800108	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800109	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781

Source: CnidoSite RNA-seq expression matrices (APALM_TPM, StringTie quantification over 84 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.