Gene detail

Detailed information of XP_074635669.1 in Acropora palmata

Genomic Location: NC_133891.1:5125766...5153863
NR annotation: XP_029190735.2, LOW QUALITY PROTEIN: nitric oxide synthase, endothelial-like [Acropora millepora]
Species Acropora palmata · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

XP_074635669.1

ATGGATTCTATCGACGGCACAGTAATAGTGAATCTAACGAAACGCAGAAAAGGTGGCGTCGGTTTTTTAGCTTGCAACACCGGCCCGTACCTCACGGTGTCACACGTGGTAAAGGGTGGCGTGGCGCATGAAACGGGTTTTATTGAAAAGGGAGATGTCATTCTTGAAGTTAATGGCAAGTCATTGGAGAAAGTGCCCTATTTAAAGGCCTTAGAAATTCTTGACCTAGCCCCAATTGGCGAGATCATGGCGTTGAAAATTCGAGCTCAAGATGGATTTCAAGCGGAACTGGAAACTGTGTTCGATTCGGAGGGAGTCGTGAGAACAGTTCGAAGGACAAGACAGTCTCCCAAAAGCGCACCAAGTACGGTGGAGAACGAGAAAATGAAAAATGAAAAAAATATGGACGCAAAGACTAATGGAGAAAAATCGGAGCCAAGTGAATTAGTGAGCCTAAGAGAATCGAAGGGTGGAACGGTGACAAACACTCTTCCAAATGCTAAAATGTCTTCTAAATGTTTAGAAGTCGTTCATGAAAATGTTAATGGCGAGAAACAAGAACAAGAGACAACGAAAGGGGAGAGACTGACTTTAAATGGAGCTGACGACGTTAAAAAGGAGCTCGAAAAAGAACAAGGGACGCTGAAGGAAAAGAAAACGACTTTACACGGATCAGATGAAACCAATAATAAGAATGATGATCCAGGGAAAGGAAGAAGTGTGTCAAATGAATCAGTTGGAATTAACAAATGTCCCGTAACCCATGCAAAGTCGCTTTACCAGCAGCCAAAGTATGTTAAGCTGCAAAATCTCCTATCCAATACTTTTACCACTGATACTCTTCATCAAAAGGCAATAGAGCCTCTCCACTGTTCCTCAGACCGTTGTTTGGGTTCCTTGATGCAGCCGTATGGTGCTTTCCCTAAGAGGCAATATGGAGTGCCCAGAGCACCCGAAGAGGTCAAACTTCACGCAAACGACTTCCTTCAACAGTATTACGACTCAATGAAACTTCAAGACAGTCCAGCTTACCATCAGCGACTGGCCGAGGTGTTGAAGGATATTGAGGAGACTGGTACTTATGAATTGGCAGAGAAGGAGCTTATCTTCGGCTGCCGTTTGGCTTGGAGGAACGCCTCGCGGTGCATAGGACGGATACAGTGGAATAAATTACACGTTTTTGATGCCAGAGGTGTGAATACTCCTGCAGAAATGTTTGAAGCGCTATGCAAGCATATAAAGTACGGCACAAACAAGGGAAACATCAGGTCCACTATAACCATCTTCCCTCAAAGAAAACGCCCATTCAAAGATTTCCGTGTGTGGAATTCTCAGCTAATTCGGTACGCTGGCTACAAGCAGTCAGATGGTTCTGTTATCGGAGACCCTGCTAATGTTGAGTTTACTGAGATCTGTGTGCAGCTTGGTTGGGAAGGCAAAGGAGGCAATTTTGATGTTTTGCCGTTAGTTCTTCAAGCTCATGGCGAGGATCCCGAGATGTTTGAAATACCTCCGGAAATAGTTCTTGAGGTGGAAATGAAACACCCGAAGTATCCTTGGTTTGAAGAGTTCGGTTTGAGGTGGTACGCTTTACCTGCTGTGTCGTGTTTGATGTTAGATGTTGGAGGAGTAGAGTTTCCCGCTTGTCCGTTTAACGGATGGTACATGGTGACAGAAATTGGGGCTCGTGACTTCGGTGATCCATGCCGCTACAACATGCTGGAGCCTGTAGCGAAGCGGATGGGCCTGGACACAAAGAGCCCAACTTCTCTTTGGAAAGACTTCGCTATGGTTGAAATAAACCTGGCAGTGCTACATAGCTTTCAGGAAGCCTCAGTTACCATCATCGATCACCACAGTTGTTCAGACTCTTTCTTGAAACACGTCGAGAACGAGGTTAAATTCCGTGGAGGATGTCCAGGGGATTGGGTATGGATCGTTCCTCCGATGTCAGGCAGCGCTACTGGTGTTTTTCATCAGGAAATGTTAAACTACTACTTGAAGCCAAGTTACGAGTATCAGGACGATCCGTGGAAACATCACAAATTTCAAAAAGGTCAAGCGGACGATGGTTTGAAAAAGAAAACAACATCATTTAAGGAAGTGGCTAAGGTAGTCAAATTCACTGCCAAAATGATGAGCAAAGCACTGGCTAAGCGACAGAAAGCTGTCATTCTTTACGCCACGGAAACAGGAAAATCTGAAAGATACGCGAAAATGCTGGGAGAACTCTTCTCGTATGTTTTTGACCCAAAGGTTATGTGCATGGAGGAGTATTCGTACCCCGACATAGAAAATGAACAGCTTGTTCTTATCGTGACCAGCACTTTTGGAAATGGAGATCCACCCGAGAATGGAGAGGGATTCGCTCGATATCTTTACGAGCTTCGACATCCATCAGATAGTGTTGAAACTTCTCACAAGAAATTATGGCAGCTCAGCAGTCTCTTGATTCAAAAAGAGAGACAAAAGCTCCTTAATTTGAAGAATGACAGTCAGCCTTTGGCTAATCTCAGGTACTCTGTCTTCGGCCTGGGGTCAAAAGCTTACCCAAACTTCTGTGCGTTTGCCCGCTCGTTGGATAATATCATTCAGGAACTTGGAGGGGAGCCTGTTCTAAAAATGGGAGAAGGAGATGAGTTGTGCGGACAAGAGGAGGCATTCAAAGTCTGGGCCAAGGCGGTATTTCAGGCCGCCTGTGACTCGTTTTGCATTAATGATGAGGTTACCAAGGAAGCGACTGACTCCATGGACAGTGTTCAAAGTGGCTGGGTACCAGGCCGCTTTCGCCTCACTAAAGCTACGCCAGCAAATGATGGAAAAACTGAACAGCTTACTGAAGGCTTGTCCCATATTTGTGGTAAAACTGTCCGTACTGCGACTTTGATGTCTGTGAAAAATTTGCAGTCCACAGATTCAAGTCGGTCAACAATTCTAGTCAAATTCAAAACAAACGATCACGCTGAATTGCAGTATAGACCGGGAGATCATGTGGCTATTTTTCCAGCCAATCATCCTGACTTGGTGCAAACTTTGATCGACAAGCTGTCAGGTGACGTTGATCCAGATGCACCGATTGCCATCGAAACATTACGGGAAACCAAAGGTAACGGACTGTTCGGCAAATCCAAGGAGTGGGAGACATTTGCACGTCTTCCTTCTCCAATCACCATACGCGAGGCGTTGGCCCGATACCTGGATATCACAAGTGTGCCCTCTCCACAGCTTATTCAATTTCTAGCTTCAATCGCGACAATCGCAGAAGATAAGGAAATTTTGCAAGTCCTTGCCGAGGGAAAAAATCAATACGAGGACTGGAAATTTGAAAACGAATGCAACATTCTTGAAGTGCTTCAAGAACATTGCTCTCTTTCAGTTCCTGCTGATTTGTTGCTTACTCAGCTCCCGCTAATGCAACCGCGCTTTTACTCTATTTCATCGTCTCCGGACCTCTGTCCTGGTGAAATACATCTCACAGTGGCTGTAGTTCATTATAACAAGAAAGGTGGAAAAGGTCCCTTGCATCGTGGTGTGTGCTCGACTTGGCTCAACAGATTACAACCTGGAGATGAGATACCCTGTTATGTCAGACAAGCCCATACCTTCCATATGCCTGAGGACACCACCGTCCCAATCATCATGGTGGGGCCTGGCACGGGCCTAGCTCCTTTCCGCAGCTTCTGGCAACAACGTCAGTATGACATCACCAACAAAGGTCATTATGGGCGTAGGGACAGTGGCGTCAGTGAATCCAGTCCTCAACAACCGGACCTTGATACTGCAACCATCAAGTGCTTGAGCCCCGCTGTTAATAAATTGGGCTCCATGTCGCTATTTTTTGGATGCAGAAATTCCAAGCAAGACTGTATTCACAAGGACGAAATGTTGAAAGCTAAAGACGAAGGGGTTTTGACGGAAATTTTCTTTGCTTTCTCGCGCGAACCCGACGCACCGAAGAAATATGTCCAAGACATGTTGAAGGAAGAAGCATTTGACATTTGCGAAAAGTTGCTAAGCAAGCAAGCCCACTTTTACGTGTGCGGTGATGTGAAAATGGCCGATGATGTTTGCAAGACTCTGCAGACACTCTTACAAGAGTACGCTGCTATGTCACAAGGAGAAGCACAAGAAACTGTCGACAAATTGAAGAGCACCGGACGGTATCATGAAGACATATTTGGAGTGACACTGAAAACACGAGAAGTTACCACGCGTATTCGATCAGCAGTCAAAAGATCACTGCATTTGCTATTCATAAAGAATCCGAAGAAAGTGATGCATCGCAGTGATACTACAATTGATTCCAATGCCAACCCAACTAGAGAAAACAAGGCTGAAGTGCGTCTAAAGAGAGCGGCGTCTGCATTCTACTAA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q9Z0J4	Nitric oxide synthase 1 OS=Mus musculus OX=10090 GN=Nos1 PE=1 SV=1
P29475	Nitric oxide synthase 1 OS=Homo sapiens OX=9606 GN=NOS1 PE=1 SV=2
Q29498	Nitric oxide synthase 1 OS=Ovis aries OX=9940 GN=NOS1 PE=2 SV=3

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0001021 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00175 all species →	NAD_binding_1	Oxidoreductase NAD-binding domain	Domain	Interproscan
PF02898 all species →	NO_synthase	Nitric oxide synthase, oxygenase domain	Domain	Interproscan
PF00667 all species →	FAD_binding_1	FAD binding domain	Domain	Interproscan
PF00258 all species →	Flavodoxin_1	Flavodoxin	Domain	Interproscan
PF00595 all species →	PDZ	PDZ domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR050607 all species →	Family	Nitric Oxide Synthase (NOS)	Interproscan
IPR001478 all species →	Domain	PDZ domain	Interproscan
IPR001433 all species →	Domain	Oxidoreductase FAD/NAD(P)-binding	Interproscan
IPR004030 all species →	Domain	Nitric oxide synthase, N-terminal	Interproscan
IPR017927 all species →	Domain	FAD-binding domain, ferredoxin reductase-type	Interproscan
IPR029039 all species →	Homologous_superfamily	Flavoprotein-like superfamily	Interproscan
IPR001094 all species →	Domain	Flavodoxin-like	Interproscan
IPR036034 all species →	Homologous_superfamily	PDZ superfamily	Interproscan
IPR008254 all species →	Domain	Flavodoxin/nitric oxide synthase	Interproscan
IPR003097 all species →	Domain	Sulfite reductase [NADPH] flavoprotein alpha-component-like, FAD-binding	Interproscan
IPR044940 all species →	Homologous_superfamily	Nitric oxide synthase, domain 2 superfamily	Interproscan
IPR012144 all species →	Family	Nitric-oxide synthase, eukaryote	Interproscan
IPR044943 all species →	Homologous_superfamily	Nitric oxide synthase, domain 1 superfamily	Interproscan
IPR036119 all species →	Homologous_superfamily	Nitric oxide synthase, N-terminal domain superfamily	Interproscan
IPR039261 all species →	Homologous_superfamily	Ferredoxin-NADP reductase (FNR), nucleotide-binding domain	Interproscan
IPR023173 all species →	Homologous_superfamily	NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily	Interproscan
IPR044944 all species →	Homologous_superfamily	Nitric oxide synthase, domain 3 superfamily	Interproscan
IPR017938 all species →	Homologous_superfamily	Riboflavin synthase-like beta-barrel	Interproscan
IPR001709 all species →	Domain	Flavoprotein pyridine nucleotide cytochrome reductase	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR43410 all species →	NITRIC OXIDE SYNTHASE OXYGENASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005515 all species →	Molecular Function	protein binding	Interproscan
GO:0016491 all species →	Molecular Function	oxidoreductase activity	Interproscan
GO:0004517 all species →	Molecular Function	nitric-oxide synthase activity	Interproscan
GO:0006809 all species →	Biological Process	nitric oxide biosynthetic process	Interproscan
GO:0010181 all species →	Molecular Function	FMN binding	Interproscan
GO:0005516 all species →	Molecular Function	calmodulin binding	Interproscan
GO:0020037 all species →	Molecular Function	heme binding	Interproscan
GO:0050660 all species →	Molecular Function	flavin adenine dinucleotide binding	Interproscan
GO:0050661 all species →	Molecular Function	NADP binding	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K13240	NOS1; nitric-oxide synthase, brain	EC:1.14.13.39	Viral myocarditis	ko05416	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.