Genomic Location: NC_133891.1:5926378...6042865
NR annotation: XP_044173762.1, LOW QUALITY PROTEIN: nesprin-1-like [Acropora millepora]
Species Acropora palmata · all data for this species · gene families
| CDS |
| XP_074635904.1 |
| Protein |
| XP_074635904.1 |
| UniProt accession | Description |
|---|---|
| Q91ZU6 | Dystonin OS=Mus musculus OX=10090 GN=Dst PE=1 SV=2 |
| Q9QXZ0 | Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4 OS=Mus musculus OX=10090 GN=Macf1 PE=1 SV=2 |
| Q03001 | Dystonin OS=Homo sapiens OX=9606 GN=DST PE=1 SV=4 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0001037 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF02187 all species → | GAS2 | Growth-Arrest-Specific Protein 2 Domain | Family | Interproscan |
| PF00435 all species → | Spectrin | Spectrin repeat | Domain | Interproscan |
| PF00307 all species → | CH | Calponin homology (CH) domain | Domain | Interproscan |
| PF17902 all species → | SH3_10 | SH3 domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR018159 all species → | Repeat | Spectrin/alpha-actinin | Interproscan |
| IPR003108 all species → | Domain | GAR domain | Interproscan |
| IPR001589 all species → | Conserved_site | Actinin-type actin-binding domain, conserved site | Interproscan |
| IPR011992 all species → | Homologous_superfamily | EF-hand domain pair | Interproscan |
| IPR001715 all species → | Domain | Calponin homology domain | Interproscan |
| IPR036872 all species → | Homologous_superfamily | CH domain superfamily | Interproscan |
| IPR002048 all species → | Domain | EF-hand domain | Interproscan |
| IPR002017 all species → | Repeat | Spectrin repeat | Interproscan |
| IPR018247 all species → | Binding_site | EF-Hand 1, calcium-binding site | Interproscan |
| IPR036534 all species → | Homologous_superfamily | GAR domain superfamily | Interproscan |
| IPR043197 all species → | Family | Plakin | Interproscan |
| IPR041615 all species → | Domain | Desmoplakin, SH3 domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR23169 all species → | ENVOPLAKIN | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0008017 all species → | Molecular Function | microtubule binding | Interproscan |
| GO:0005515 all species → | Molecular Function | protein binding | Interproscan |
| GO:0005509 all species → | Molecular Function | calcium ion binding | Interproscan |
| GO:0005198 all species → | Molecular Function | structural molecule activity | Interproscan |
| GO:0005737 all species → | Cellular Component | cytoplasm | Interproscan |
| GO:0005882 all species → | Cellular Component | intermediate filament | Interproscan |
| GO:0016020 all species → | Cellular Component | membrane | Interproscan |
| GO:0042060 all species → | Biological Process | wound healing | Interproscan |
| GO:0045104 all species → | Biological Process | intermediate filament cytoskeleton organization | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K10382 | DST; dystonin | - | Cytoskeleton proteins | ko04812 | deepkoala |
Transcript abundance of XP_074635904.1 across 84 RNA-seq samples of Acropora palmata. This gene has no row in the species' RNA-seq expression matrix, so every value below is shown as zero — the matrix simply does not cover this transcript. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| all_coral_tissue · exposed | 46 | 0 | 0.00 | 0.00 | |
| all_coral_tissue · baseline | 38 | 0 | 0.00 | 0.00 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| SRR8800026 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800027 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800028 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800029 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800033 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800034 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800036 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800038 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800039 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800040 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800042 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800044 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800045 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800047 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800051 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800053 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800056 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800058 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800060 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800061 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800062 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800063 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800065 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800066 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800068 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800071 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800073 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800075 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800077 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800079 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800080 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800083 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800086 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800087 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800088 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800089 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800091 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800092 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800093 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800094 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800095 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800097 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800099 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800100 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800105 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800107 | all_coral_tissue · exposed | all_coral_tissue | not recorded | exposed | SRP189781 | 0.00 |
| SRR8800030 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800031 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800032 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800035 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800037 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800041 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800043 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800046 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800048 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800049 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800050 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800052 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800054 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800055 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800057 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800059 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800064 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800067 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800069 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800070 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800072 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800074 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800076 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800078 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800081 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800082 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800084 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800085 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800090 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800096 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800098 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800101 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800102 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800103 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800104 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800106 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800108 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
| SRR8800109 | all_coral_tissue · baseline | all_coral_tissue | not recorded | baseline | SRP189781 | 0.00 |
Source: CnidoSite RNA-seq expression matrices (APALM_TPM,
StringTie quantification over 84 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
Genes whose expression across the transcriptome samples of Acropora palmata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
| Direction | Partners | Most correlated partner | PCC |
|---|---|---|---|
| Positively correlated | 0 | not in this network | - |
| Negatively correlated | 0 | not in this network | - |
This gene has no edge at all in the Acropora palmata network, in either direction — it is not one of the genes the network was built from (the network covers genes with enough expression variation across the transcriptome samples). The counts above are a property of the network, not a failed lookup.
Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.
Whether this gene can be visualised in the single-cell atlases of Acropora palmata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
| Sample | Methylation profile |
|---|---|
| Polyp_Underside_Control_2 | open |
| Polyp_Underside_Control_3 | open |
| Polyp_Underside_Treatment_1 | open |
| Polyp_Upperside_Control_1 | open |
| Polyp_Upperside_Treatment_3 | open |
| Polyp_Upperside_Treatment_4 | open |
The DNA Methylation page locates this gene by scanning the bisulphite table, which holds one row per cytosine. For the largest datasets that scan takes a while to return; it does not mean the link is broken.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
