Gene detail

Detailed information of XP_074635932.1 in Acropora palmata

Genomic Location: NC_133891.1:9108580...9131094
NR annotation: XP_029191979.2, GATOR complex protein DEPDC5-like isoform X2 [Acropora millepora]
Species Acropora palmata · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

XP_074635932.1

ATGAAGCTTTTCAAGTTATGGGTCCATCAGCAAACCTTCAGTGAGGATGAACTTATCCTTAATCCGAAGGATTTTCCGAACGAAAACGTGGGAGACATTCTGGAGATCCACCACCCAGACAAAGATAACAGTAGTTTACTCCTGCAGATCAAATCTATTAGCCCCGATTTCCAACAAAAGGATACAATTAGCATCGAACAATCTGTCGCTAACATCTTCCAACTAAGAACATACAGGGATGTCGAAGTTACAAAAGTTGAACCGCACGATGTGTCCGTCGACATGGTGGAAGTTTTGTTAAAGGACCAGTTCGCTACGAGGAGCGAGATGTGGCGATTCTCGAAAGACTTAGTAGGCTCATGTGTTTATGTTGCCAAGAAGTTGAAGCATTCAGGGATTCGTGCACAGGTGAATGAGATCTGGTGTAACGGGGAGAAGGTTTCATGTGGAGTCATATCGAAGGACACAAGGGTGGTTTTTAGATCTTGCAGCTCAAAGTTGTATTTGTTCATACAAATGAGTAAAGAAATGTGGGACTTTGATTTTAATGGAGATCTTTTCTTTGAGAAAGCTATCAATGGATTCCTTCGTGAACTGTTTACCAAATGGAAAGAGCTTACAGTCAGCCATGATGTCAGCATTATACTCTTTTCAAGGACCTTCTATGATGCACAGTCAATTGGTGACTTTCCATCAAGTCCTTCAAGGAGTATTCAACAGGATCCATATGGGAGATTTTATGAAGATTTTTATCAAGTGGTTGCTTTGAACGAGAGACAAGATGACTGGATTCCAGTTCTTGTGACTTTAAAACAATGTTTTAATCAATATCCAACAATCACTGGTTACTCTGGCGACACATCTAAAGGTGGTAACATTATTGGAAGCAACTCCAGCTCTCTTGATGGGAATTTTTTAGAGGCAATTAACTTGTCCATGAATGCAATTAGGAGGCACCATATTGATCGCAATTTTGAACGCACTGGCCATACTATCATCATTGTCTCACCGGGCTCTGGAGTGTTTGAAGTTGACCGAGAATTGACCAGCATCACTAAACAAAGAATACTTGATAGTGGTGTTTCCATTGATCTTGTGTGTTTAGCGGAGCAGCCGCTGCATACTGTTCCACTGTTAAAATACTTCAATAAGGTGCTTGGAAAAAGGGATGGTAACCTGGCAGATGACTATAACATCCCACACTGGATGAATCACAACTTCTATGCCTCATCAAAGACAAGAAACAAGGGAGAGACCTATGTCCCGCGTATAAAAGTTCCAGAAGTCATGTTAAACTCTGTGGGGAGAAGAAGTGAAGATGGAAAAGAACCTTACACGTACTTTACAGAACATGACAAACCAGATGCAAGCAGCTGTCAGTTGCTGGACCTGGTCGACTATGATGAATATGACAGGAACGTCTTCAGAAACCCTTCGAGATGCTCTACAAAGCGAGGATTTCGACCTCGAGGTTCAGGATTCAAGCGAATAGGAAGCGCATTGGAGATGGCAAGAATGGCGAAATCGGTATCCAAGGACGAAATGATGTTTCGAAAGACATCCTCGCCTCCAATGGGCGTGTCCTCATTTGATGACGTCGAATTGAACTCGTCATCTTCGGGCGCAGTGAAACGAGATACCTATTCCTTTAGAGATGTGGATAACAGAACACAATATATGTCTTCTTCAGTGGAGTGCACTTCACAGGGTGTCTTTGAAAATGTTTCCAAAAGTACTTCTCAGTGCAGCGTCACTCGACCAGTACGTCAGCGGTTTGCTGTGAGTAGCGCAGACGCAGATCCCTCCTTGGTCCTGCCTAAGGAACCAGTCCGCCCTCAAAGGACTCTGATAAACCCGTTTAAACCAAACCAGATTCCATGTAACTGGATATGCAATAAGCATCGCTGGTCTCATGTTTTCGCTACTGGACCAGATGGAGAGATCCTTCATCGACACTATCACAAGCTTGCCCCAGCTAATGACGAGGCTGAAAAGACCGAGAAACCTGAAAAGTCGCGCGGTGTCGAGGAAGCTGCCCTTGTTGTCGTAGCGGCACGGAAACGTGAAATGTCTGAAGCTTCGCGTAGTATTTCAGAAGATCAAGTACTTTTTGAAGAAGCGATAACGAGCGGAGGAAGTGACGATACAGACGAAGACACTACCTTCTCTGCAGAGGAGCCCATGAGGGGCAATCGCGAGCATTTTAGCCCAGCCCATGTTGGGGCTCTAACCTCCCAACTGAACACCCCCCGTAGACGTACGTTACCTCGGATTTACAATCTATCCCGCAAGGGAGATGTGCCTGTCGAGAATGACTGGACAGCGGCTGTTAAGACAAGTGTTGATTGGAAATCTATGACTTGTCCCGCACTGTTGCCCTTGACAACCGATATCTGTCCAAGCAAGAAAACCCTGGAGTCGGATTACGTAGAGTCCAATTACAAACTATTCATTGAGGAAGAGGAGGATTTGGCGGATGAAATGAGGGGACATGACGGCGTTCATGACGATGATGCCCAGGGAACTGCTCGACGTTTGAGTGCAGAGATAATTTTTACAGAACTTATATCGCAACGAATTCGAAAGGGATTTCAGTTAATTGCGCCAAAGAGCCAACCAGGCGTCGCCGACAAGCCCCAGTCCTTTGCAACCATTCCAGTGAAGTCTGACGTTCAGACGTACTTCCTGAGCATCGGCCGGATATCACACAAGCTGACTCTGACGTCACCGGAAGTAACGGTTATCAAATACAGACCACGTCACTTGCAGGTTACAGAACCCAAGAGCTATAGCTATCGCCTGTGGATCCCACAAAGACAAGTGTTTGAAGCAAATAATAGCAGATTCTTGCATGAAGAGATTGATAGCTACAATTGGAATTACCTGGACCAACATATCTGTGGAGACACGGAGTTTGATGAGCTCATCGAGCCTCTGGATTACTGGAAGGCTCGTTTTCTTGTGCTTCCCTTTTCTCAGCGTAAACTGCCCCAGGCAGATAAAAACAAGACCCCAGTTTCTTTTGATGACAATCTCATGGAAGGCTTTCTTAAGTTTCTGGAAGTTCTCAATCGAATAAAGCGATTCCAGAAAGGAACACAATCTCAAAAGGAAAGAAGGTCGTTGGAGCCTTGTTATCCGTCTCGCCGCTTTTACAAACAACATGACATGAAAGCATCCTCACCTCTCCCCTCTGAGCTGTCGGGGATCAGAGAAAACGCTTCCTTGCCGGGGACTCCGCTGAGCAGTAGATTACGGTCTCCCTCTTCCTCAGGCCAAGAGTTCTCAAGTGTGGATTCTCGTAGCATTTCCTCTCAAGAACTGATTAGCGAACAGCTGAATGGCGGTGAGGACTCGCAAGTTCCCTATGACAGAAACAGAATCATCTTTCATTCACTGGAAACTATTGCCGAAGCAATGATGGATACGGGAAAAGGTCTTTCCTTTCTCCCGGAAGTAAAAGGATTAAAGCCGTTCAGTTTCCTTAGCGTGGAGGCCATCTTATGGATCACTCAACACGTGGATGGTGTTACTTCAAAAGAGCAAGCCATTCAACTGTGCCAAAATATGGTTGAGAGGGGTATTATCCAACACGCTTCGGGAAGCGCCAAGCAGAAACTAGTGGAAGGTTTCATCATATTTTTCTTCACCCCAAGAAAGTCTTGGGCCGAGAAAACGGAAGAGATCATGGACACCTCTAAATTCTCCGTACCCCACCGAAGCTCAATCGACGTAGAGCGATTGGAGTGCAATCTTCTAAGAGCCTTTCAAACCGAATGGTTTGAGGTCGCGCTTTGGGGGCGCAAAATGGAAGAAGATTTTCCAGAATTCCTGGCAACTGACCACAGCGTCGGGACATTTCAAGCGAGTTATCCGAACTTGAAGCGAGGTGGACCGAATTCGGCCCGGCGTAATTCTGCGAACTTTCACTTGGAGAATGGTTGTAATTGTGTTCCCGCCTACAAGCTCGTCAAATTGGATGCTGACTATCAGCGCAAAAGCCAACGCCCAGAATCCTGTACTGTCCGTTACCATGGTAACTTCTGTCCGCTCCATGCCTTCGAGATTGAGTTGCACTGGGTTGCGGCAACTGGGGGAATTGTCAACGACATGGTTCAGTCGTGGACCAGAAAAGCTCCATCTTGTGGCTTTCATATAGTCCCCGTTCCTGTAAGTCCATTTCCTGATCCAGTTGGTAAGAATGTGGAGCCTTTCCGTCTGCCTGTGTTCATACCGCTCAACTTGACCAACTGTACTTCAAATGGATCCCCTCTGTTCCAAGAGTTTGATCCAGCAAGGCAACATTTTAGAATGTTTTTATTTTTGGAGGCTATTCTTCAAAGGTTTGGCTTCATCCGGGATTCGCCGTTTGGTTCGATACACGTGAATGCACCTATGGTTCAATTCACGCCGGTACAGTGTCGCGAGAATGATTACGTGCACACGAGCGGTGTCGCGTTCGTCCGAATCTTAACTTGGGAAGAAGATGATGATCCGTTTGGTTCCAGTATATCCAGCGTAGAAGGGAGCAAGCCTTGCACAGGGTTCCATTGGATGCCAAACTATATGCTAACTAAGCGCTGGAGATCAGCTGCGACCGGCGACAAAGACGCTAGCAGCAAATTGAGAAGTAAATTGGAAGACTTTTGCGCCGACGATAATGGTGTGCTCACGGCATTTTGGGAATCGTGTAAAGAAAAGGCGAGGAAAGTAGCGGAGAACAGATTAGACGAGGAGGAAATAACCATCTTGGGAGATACAGAAATAGACAGGACTGAACAAAATAGGAAGGAAATAGGTGATTCACCCGAGGTAGAGAAGTCAGACCGTACTGTATCTAGTGACTCATAA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
O75140	GATOR1 complex protein DEPDC5 OS=Homo sapiens OX=9606 GN=DEPDC5 PE=1 SV=2
P61460	GATOR1 complex protein DEPDC5 OS=Mus musculus OX=10090 GN=Depdc5 PE=1 SV=2
Q9W0E3	GATOR complex protein Iml1 OS=Drosophila melanogaster OX=7227 GN=Iml1 PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0003122 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF12257 all species →	IML1	Vacuolar membrane-associated protein Iml1	Family	Interproscan
PF19418 all species →	DEPDC5_CTD	DEPDC5 protein C-terminal region	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR048255 all species →	Domain	Vacuolar membrane-associated protein Iml1, N-terminal domain	Interproscan
IPR045838 all species →	Domain	DEPDC5, C-terminal	Interproscan
IPR036390 all species →	Homologous_superfamily	Winged helix DNA-binding domain superfamily	Interproscan
IPR036388 all species →	Homologous_superfamily	Winged helix-like DNA-binding domain superfamily	Interproscan
IPR000591 all species →	Domain	DEP domain	Interproscan
IPR027244 all species →	Family	Vacuolar membrane-associated protein Iml1	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR13179 all species →	DEP DOMAIN CONTAINING PROTEIN 5	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0035556 all species →	Biological Process	intracellular signal transduction	Interproscan
GO:0005096 all species →	Molecular Function	GTPase activator activity	Interproscan
GO:0005765 all species →	Cellular Component	lysosomal membrane	Interproscan
GO:0010508 all species →	Biological Process	positive regulation of autophagy	Interproscan
GO:0034198 all species →	Biological Process	cellular response to amino acid starvation	Interproscan
GO:1904262 all species →	Biological Process	negative regulation of TORC1 signaling	Interproscan
GO:1990130 all species →	Cellular Component	GATOR1 complex	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K20404	DEPDC5, SEA1; SEA/GATOR complex protein SEA1/DEPDC5	-	Membrane trafficking	ko04131	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of XP_074635932.1 across 84 RNA-seq samples of Acropora palmata. This gene has no row in the species' RNA-seq expression matrix, so every value below is shown as zero — the matrix simply does not cover this transcript. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

84Samples

0TPM > 0

2Conditions

0.0Max TPM

0.0Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM	Mean, relative to max
all_coral_tissue · exposed	46	0	0.00	0.00
all_coral_tissue · baseline	38	0	0.00	0.00

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study
SRR8800026	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800027	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800028	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800029	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800033	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800034	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800036	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800038	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800039	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800040	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800042	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800044	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800045	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800047	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800051	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800053	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800056	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800058	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800060	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800061	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800062	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800063	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800065	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800066	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800068	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800071	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800073	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800075	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800077	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800079	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800080	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800083	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800086	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800087	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800088	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800089	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800091	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800092	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800093	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800094	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800095	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800097	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800099	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800100	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800105	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800107	all_coral_tissue · exposed	all_coral_tissue	not recorded	exposed	SRP189781
SRR8800030	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800031	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800032	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800035	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800037	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800041	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800043	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800046	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800048	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800049	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800050	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800052	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800054	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800055	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800057	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800059	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800064	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800067	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800069	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800070	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800072	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800074	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800076	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800078	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800081	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800082	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800084	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800085	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800090	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800096	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800098	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800101	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800102	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800103	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800104	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800106	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800108	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781
SRR8800109	all_coral_tissue · baseline	all_coral_tissue	not recorded	baseline	SRP189781

Source: CnidoSite RNA-seq expression matrices (APALM_TPM, StringTie quantification over 84 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.