Gene detail

Detailed information of XP_074636747.1 in Acropora palmata

Genomic Location: NC_133891.1:6945809...6954177
NR annotation: XP_029213186.2, mevalonate kinase-like isoform X4 [Acropora millepora]
Species abbreviation APALM · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q9R008	Mevalonate kinase OS=Mus musculus OX=10090 GN=Mvk PE=1 SV=1
Q03426	Mevalonate kinase OS=Homo sapiens OX=9606 GN=MVK PE=1 SV=1
Q5E9T8	Mevalonate kinase OS=Bos taurus OX=9913 GN=MVK PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0004686 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00288 all species →	GHMP_kinases_N	GHMP kinases N terminal domain	Family	Interproscan
PF08544 all species →	GHMP_kinases_C	GHMP kinases C terminal	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR036554 all species →	Homologous_superfamily	GHMP kinase, C-terminal domain superfamily	Interproscan
IPR006204 all species →	Domain	GHMP kinase N-terminal domain	Interproscan
IPR006205 all species →	Family	Mevalonate kinase	Interproscan
IPR013750 all species →	Domain	GHMP kinase, C-terminal domain	Interproscan
IPR006203 all species →	Conserved_site	GHMP kinase, ATP-binding, conserved site	Interproscan
IPR014721 all species →	Homologous_superfamily	Small ribosomal subunit protein uS5 domain 2-type fold, subgroup	Interproscan
IPR020568 all species →	Homologous_superfamily	Ribosomal protein uS5 domain 2-type superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR43290 all species →	MEVALONATE KINASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005524 all species →	Molecular Function	ATP binding	Interproscan
GO:0004496 all species →	Molecular Function	mevalonate kinase activity	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0005829 all species →	Cellular Component	cytosol	Interproscan
GO:0006695 all species →	Biological Process	cholesterol biosynthetic process	Interproscan
GO:0008299 all species →	Biological Process	isoprenoid biosynthetic process	Interproscan
GO:0019287 all species →	Biological Process	isopentenyl diphosphate biosynthetic process, mevalonate pathway	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K00869	MVK, mvaK1; mevalonate kinase	EC:2.7.1.36	Peroxisome	ko04146	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.