Detailed information of XP_074636770.1 in Acropora palmata

Genomic Location: NC_133891.1:18634631...18648724
NR annotation: XP_029194575.2, DNA replication ATP-dependent helicase/nuclease DNA2-like isoform X1 [Acropora millepora]
Species Acropora palmata · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
Q8QHA5DNA replication ATP-dependent helicase/nuclease DNA2 OS=Xenopus laevis OX=8355 GN=dna2 PE=1 SV=1
D3ZG52DNA replication ATP-dependent helicase/nuclease DNA2 OS=Rattus norvegicus OX=10116 GN=Dna2 PE=3 SV=1
E1BMP7DNA replication ATP-dependent helicase/nuclease DNA2 OS=Bos taurus OX=9913 GN=DNA2 PE=3 SV=3
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0003019 (this species only)

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF13086
all species →
AAA_11AAA domainDomainInterproscan
PF21123
all species →
Dna2_RiftDna2 Rift barrel domainDomainInterproscan
PF08696
all species →
Dna2DNA replication factor Dna2FamilyInterproscan
PF13087
all species →
AAA_12AAA domainDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR041677
all species →
DomainDNA2/NAM7 helicase, helicase domainInterproscan
IPR048459
all species →
DomainDNA2, rift barrel domainInterproscan
IPR027417
all species →
Homologous_superfamilyP-loop containing nucleoside triphosphate hydrolaseInterproscan
IPR045055
all species →
FamilyDNA2/NAM7-like helicaseInterproscan
IPR047187
all species →
DomainUpf1-like, C-terminal helicase domainInterproscan
IPR026851
all species →
DomainDNA replication ATP-dependent helicase/nuclease Dna2/JHS1, DEXXQ-box helicase domainInterproscan
IPR014808
all species →
DomainDNA replication factor Dna2, N-terminalInterproscan
IPR041679
all species →
DomainDNA2/NAM7 helicase-like, C-terminalInterproscan
IPR011604
all species →
Homologous_superfamilyPD-(D/E)XK endonuclease-like domain superfamilyInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR10887
all species →
DNA2/NAM7 HELICASE FAMILYInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0004386
all species →
Molecular Functionhelicase activityInterproscan
GO:0005737
all species →
Cellular ComponentcytoplasmInterproscan
GO:0017108
all species →
Molecular Function5'-flap endonuclease activityInterproscan
GO:0071932
all species →
Biological Processreplication fork reversalInterproscan
GO:0017116
all species →
Molecular Functionsingle-stranded DNA helicase activityInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K10742DNA2; DNA replication ATP-dependent helicase/nuclease Dna2EC:5.6.2.3
EC:3.1.-.-
DNA replication proteinsko03032deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of XP_074636770.1 across 84 RNA-seq samples of Acropora palmata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

84Samples
13TPM > 0
2Conditions
2.0Max TPM
0.2Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
all_coral_tissue · exposed 46 9 0.24 2.03
all_coral_tissue · baseline 38 4 0.13 1.95

Per sample · hover a bar for the full sample record · show / hide the sample table

Source: CnidoSite RNA-seq expression matrices (APALM_TPM, StringTie quantification over 84 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

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