Detailed information of XP_074637528.1 in Acropora palmata

Genomic Location: NC_133891.1:21081349...21090299
NR annotation: XP_029188708.2, LOW QUALITY PROTEIN: SH2B adapter protein 2-like [Acropora millepora]
Species Acropora palmata · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
Q91ZM2SH2B adapter protein 1 OS=Mus musculus OX=10090 GN=Sh2b1 PE=1 SV=2
Q62985SH2B adapter protein 1 OS=Rattus norvegicus OX=10116 GN=Sh2b1 PE=1 SV=1
Q9NRF2SH2B adapter protein 1 OS=Homo sapiens OX=9606 GN=SH2B1 PE=1 SV=3
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0005604 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF08916
all species →		Phe_ZIPPhenylalanine zipperDomainInterproscan
PF00017
all species →		SH2SH2 domainDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR036860
all species →		Homologous_superfamilySH2 domain superfamilyInterproscan
IPR001849
all species →		DomainPleckstrin homology domainInterproscan
IPR030523
all species →		FamilySH2B adapter proteinInterproscan
IPR000980
all species →		DomainSH2 domainInterproscan
IPR015012
all species →		DomainPhenylalanine zipperInterproscan
IPR035057
all species →		DomainSH2B1, SH2 domainInterproscan
IPR011993
all species →		Homologous_superfamilyPH-like domain superfamilyInterproscan
IPR036290
all species →		Homologous_superfamilyPhenylalanine zipper superfamilyInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR10872
all species →		SH2B ADAPTER PROTEINInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0005068
all species →		Molecular Functiontransmembrane receptor protein tyrosine kinase adaptor activityInterproscan
GO:0005886
all species →		Cellular Componentplasma membraneInterproscan
GO:0007165
all species →		Biological Processsignal transductionInterproscan
GO:0035556
all species →		Biological Processintracellular signal transductionInterproscan
GO:0035591
all species →		Molecular Functionsignaling adaptor activityInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
No KEGG orthology assignment for XP_074637528.1.

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of XP_074637528.1 across 84 RNA-seq samples of Acropora palmata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

84Samples
67TPM > 0
2Conditions
68.6Max TPM
26.4Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
all_coral_tissue · exposed 46 36 22.88 68.58
all_coral_tissue · baseline 38 31 30.56 60.39

Per sample · hover a bar for the full sample record

Show the sample table (84 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
SRR8800066 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 68.58
SRR8800077 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 45.30
SRR8800105 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 43.24
SRR8800097 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 41.96
SRR8800056 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 40.80
SRR8800068 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 40.64
SRR8800092 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 39.76
SRR8800071 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 39.10
SRR8800044 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 37.76
SRR8800080 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 36.32
SRR8800051 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 36.09
SRR8800083 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 35.54
SRR8800100 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 34.12
SRR8800036 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 33.72
SRR8800079 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 33.61
SRR8800099 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 33.22
SRR8800093 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 31.35
SRR8800038 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 28.59
SRR8800045 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 28.18
SRR8800073 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 27.51
SRR8800034 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 26.64
SRR8800053 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 25.37
SRR8800033 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 23.03
SRR8800107 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 20.64
SRR8800040 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 20.36
SRR8800091 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 19.79
SRR8800047 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 19.04
SRR8800065 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 18.47
SRR8800063 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 18.19
SRR8800095 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 17.74
SRR8800060 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 17.68
SRR8800062 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 16.81
SRR8800058 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 14.50
SRR8800088 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 13.22
SRR8800089 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 12.81
SRR8800087 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 12.77
SRR8800026 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 0.00
SRR8800027 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 0.00
SRR8800028 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 0.00
SRR8800029 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 0.00
SRR8800039 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 0.00
SRR8800042 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 0.00
SRR8800061 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 0.00
SRR8800075 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 0.00
SRR8800086 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 0.00
SRR8800094 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 0.00
SRR8800032 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 60.39
SRR8800067 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 54.59
SRR8800069 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 53.15
SRR8800096 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 48.77
SRR8800109 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 48.59
SRR8800106 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 47.89
SRR8800078 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 47.61
SRR8800098 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 47.21
SRR8800072 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 45.86
SRR8800076 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 44.79
SRR8800074 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 43.68
SRR8800035 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 43.30
SRR8800108 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 41.78
SRR8800041 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 40.69
SRR8800048 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 40.22
SRR8800104 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 39.27
SRR8800043 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 38.90
SRR8800049 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 36.39
SRR8800101 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 36.15
SRR8800050 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 34.95
SRR8800082 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 34.84
SRR8800037 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 34.48
SRR8800057 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 34.08
SRR8800081 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 33.66
SRR8800102 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 24.58
SRR8800103 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 21.23
SRR8800084 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 20.48
SRR8800090 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 19.10
SRR8800085 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 17.39
SRR8800070 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 13.85
SRR8800064 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 13.31
SRR8800030 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 0.00
SRR8800031 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 0.00
SRR8800046 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 0.00
SRR8800052 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 0.00
SRR8800054 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 0.00
SRR8800055 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 0.00
SRR8800059 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 0.00

Source: CnidoSite RNA-seq expression matrices (APALM_TPM, StringTie quantification over 84 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Acropora palmata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated39XP_074624815.10.909450404437958
Negatively correlated3XP_074639658.1-0.742030926444559

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Acropora palmata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

DNA methylation (bisulphite samples)

SampleMethylation profile
Polyp_Underside_Control_2open
Polyp_Underside_Control_3open
Polyp_Underside_Treatment_1open
Polyp_Upperside_Control_1open
Polyp_Upperside_Treatment_3open
Polyp_Upperside_Treatment_4open

The DNA Methylation page locates this gene by scanning the bisulphite table, which holds one row per cytosine. For the largest datasets that scan takes a while to return; it does not mean the link is broken.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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