Detailed information of XP_074638262.1 in Acropora palmata

Genomic Location: NC_133892.1:4827711...4836478
NR annotation: XP_029189738.2, protein disulfide-isomerase 2-like [Acropora millepora]
Species Acropora palmata · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
Q17770Protein disulfide-isomerase 2 OS=Caenorhabditis elegans OX=6239 GN=pdi-2 PE=1 SV=1
Q5R5B6Protein disulfide-isomerase OS=Pongo abelii OX=9601 GN=P4HB PE=2 SV=1
P07237Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0001207 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF00085
all species →		ThioredoxinThioredoxinDomainInterproscan
PF13848
all species →		Thioredoxin_6Thioredoxin-like domainDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR036249
all species →		Homologous_superfamilyThioredoxin-like superfamilyInterproscan
IPR017937
all species →		Conserved_siteThioredoxin, conserved siteInterproscan
IPR013766
all species →		DomainThioredoxin domainInterproscan
IPR005792
all species →		FamilyProtein disulphide isomeraseInterproscan
IPR005788
all species →		DomainProtein disulfide-isomerase, thioredoxin-like domainInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR18929
all species →		PROTEIN DISULFIDE ISOMERASEInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0003756
all species →		Molecular Functionprotein disulfide isomerase activityInterproscan
GO:0005783
all species →		Cellular Componentendoplasmic reticulumInterproscan
GO:0006457
all species →		Biological Processprotein foldingInterproscan
GO:0034976
all species →		Biological Processresponse to endoplasmic reticulum stressInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K09580PDIA1, P4HB; protein disulfide-isomerase A1EC:5.3.4.1
Exosomeko04147deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of XP_074638262.1 across 84 RNA-seq samples of Acropora palmata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

84Samples
84TPM > 0
2Conditions
1,851.1Max TPM
599.1Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
all_coral_tissue · exposed 46 46 653.51 1,851.09
all_coral_tissue · baseline 38 38 533.31 1,092.25

Per sample · hover a bar for the full sample record

Show the sample table (84 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
SRR8800045 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 1,851.09
SRR8800066 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 1,522.92
SRR8800042 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 1,335.55
SRR8800093 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 1,326.29
SRR8800080 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 1,237.42
SRR8800092 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 1,233.22
SRR8800105 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 1,220.21
SRR8800083 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 1,158.75
SRR8800075 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 1,113.73
SRR8800036 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 1,064.63
SRR8800100 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 1,063.41
SRR8800099 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 1,030.15
SRR8800039 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 1,014.32
SRR8800097 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 1,001.83
SRR8800068 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 989.15
SRR8800056 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 974.84
SRR8800038 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 928.14
SRR8800079 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 897.76
SRR8800051 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 783.64
SRR8800077 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 745.82
SRR8800053 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 708.90
SRR8800073 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 677.50
SRR8800033 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 641.92
SRR8800071 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 631.02
SRR8800034 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 614.05
SRR8800044 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 529.47
SRR8800091 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 369.70
SRR8800086 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 323.06
SRR8800028 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 306.79
SRR8800058 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 290.70
SRR8800060 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 262.84
SRR8800063 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 210.63
SRR8800047 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 195.70
SRR8800107 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 190.61
SRR8800062 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 179.26
SRR8800088 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 178.15
SRR8800061 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 167.85
SRR8800065 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 156.44
SRR8800095 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 143.35
SRR8800027 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 137.50
SRR8800089 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 126.83
SRR8800040 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 123.75
SRR8800094 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 112.64
SRR8800026 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 102.30
SRR8800087 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 96.50
SRR8800029 all_coral_tissue · exposed all_coral_tissue not recorded exposed SRP189781 91.30
SRR8800106 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 1,092.25
SRR8800057 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 1,022.53
SRR8800078 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 815.12
SRR8800098 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 813.47
SRR8800101 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 786.45
SRR8800104 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 755.52
SRR8800109 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 724.33
SRR8800048 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 724.17
SRR8800037 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 717.59
SRR8800108 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 711.46
SRR8800041 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 704.71
SRR8800052 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 679.72
SRR8800049 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 672.79
SRR8800069 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 663.38
SRR8800043 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 654.49
SRR8800096 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 651.61
SRR8800035 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 619.47
SRR8800076 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 613.56
SRR8800050 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 608.01
SRR8800032 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 571.27
SRR8800081 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 532.95
SRR8800046 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 526.50
SRR8800067 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 522.86
SRR8800072 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 509.42
SRR8800082 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 497.61
SRR8800074 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 490.21
SRR8800102 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 445.30
SRR8800103 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 445.09
SRR8800055 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 247.98
SRR8800031 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 243.52
SRR8800070 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 223.88
SRR8800059 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 223.46
SRR8800084 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 206.69
SRR8800085 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 121.69
SRR8800090 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 121.41
SRR8800064 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 116.15
SRR8800054 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 99.90
SRR8800030 all_coral_tissue · baseline all_coral_tissue not recorded baseline SRP189781 89.36

Source: CnidoSite RNA-seq expression matrices (APALM_TPM, StringTie quantification over 84 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Acropora palmata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated46XP_074607263.10.925942733825931
Negatively correlated8XP_074631460.1-0.767113078836634

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Acropora palmata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

DNA methylation (bisulphite samples)

SampleMethylation profile
Polyp_Underside_Control_2open
Polyp_Underside_Control_3open
Polyp_Underside_Treatment_1open
Polyp_Upperside_Control_1open
Polyp_Upperside_Treatment_3open
Polyp_Upperside_Treatment_4open

The DNA Methylation page locates this gene by scanning the bisulphite table, which holds one row per cytosine. For the largest datasets that scan takes a while to return; it does not mean the link is broken.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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