Genomic Location: sc0000099_pilon:176819...217195
NR annotation: XP_044177834.1, intersectin-1-like [Acropora millepora]
| CDS | |||||
| aacu_s0099.g13.t1 | |||||
| Transcript |
| aacu_s0099.g13.t1 |
| Protein |
| aacu_s0099.g13.t1 |
| Uniprot term | Description | ||||
|---|---|---|---|---|---|
| O42287 | Intersectin-1 OS=Xenopus laevis OX=8355 GN=itsn1 PE=1 SV=2 | ||||
| Q9WVE9 | Intersectin-1 OS=Rattus norvegicus OX=10116 GN=Itsn1 PE=1 SV=2 | ||||
| Q15811 | Intersectin-1 OS=Homo sapiens OX=9606 GN=ITSN1 PE=1 SV=3 |
| Gene family | Subfamily |
|---|---|
| Ubiquitin Family | UBD|Other|SH3 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00621 | RhoGEF | RhoGEF domain | Domain | Interproscan |
| PF16652 | PH_13 | Pleckstrin homology domain | Domain | Interproscan |
| PF00168 | C2 | C2 domain | Domain | Interproscan |
| PF00018 | SH3_1 | SH3 domain | Domain | Interproscan |
| PF14604 | SH3_9 | Variant SH3 domain | Domain | Interproscan |
| PF12763 | EF-hand_4 | Cytoskeletal-regulatory complex EF hand | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR000261 | Domain | EH domain | Interproscan |
| IPR001452 | Domain | SH3 domain | Interproscan |
| IPR001331 | Conserved_site | Guanine-nucleotide dissociation stimulator, CDC24, conserved site | Interproscan |
| IPR035899 | Homologous_superfamily | Dbl homology (DH) domain superfamily | Interproscan |
| IPR036028 | Homologous_superfamily | SH3-like domain superfamily | Interproscan |
| IPR002048 | Domain | EF-hand domain | Interproscan |
| IPR000219 | Domain | Dbl homology (DH) domain | Interproscan |
| IPR001849 | Domain | Pleckstrin homology domain | Interproscan |
| IPR000008 | Domain | C2 domain | Interproscan |
| IPR035892 | Homologous_superfamily | C2 domain superfamily | Interproscan |
| IPR011992 | Homologous_superfamily | EF-hand domain pair | Interproscan |
| IPR018247 | Binding_site | EF-Hand 1, calcium-binding site | Interproscan |
| IPR051480 | Family | Endocytic & GEF Adapter | Interproscan |
| IPR011993 | Homologous_superfamily | PH-like domain superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR46006 | RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR AT 64C, ISOFORM A | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0005085 | Molecular Function | guanyl-nucleotide exchange factor activity | Interproscan |
| GO:0035556 | Biological Process | intracellular signal transduction | Interproscan |
| GO:0005509 | Molecular Function | calcium ion binding | Interproscan |
| GO:0035025 | Biological Process | positive regulation of Rho protein signal transduction | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K20045 | ITSN; intersectin | - | Membrane trafficking | ko04131 | deepkoala |
Maintained by Dr. Jiajie She from Prof. Longjun Wu's Lab & Prof. Pei-yuan Qian's Lab
Hong Kong Branch of the Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou)
Hong Kong University of Science and Technology
Clear Water Bay, Kowloon, Hong Kong
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