Gene detail

Detailed information of aawi_s0049.g5.t2 in Acropora awi

Genomic Location: sc0000049_pilon:71646...79640
NR annotation: XP_029190449.2, beta-secretase 2-like isoform X1 [Acropora millepora]

Gene Structure

Sequence

Uniprot

Uniprot term	Description
Q2HJ40	Beta-secretase 1 OS=Bos taurus OX=9913 GN=BACE1 PE=2 SV=1
P56819	Beta-secretase 1 OS=Rattus norvegicus OX=10116 GN=Bace1 PE=2 SV=1
P56817	Beta-secretase 1 OS=Homo sapiens OX=9606 GN=BACE1 PE=1 SV=3

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00026	Asp	Eukaryotic aspartyl protease	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR001461	Family	Aspartic peptidase A1 family	Interproscan
IPR021109	Homologous_superfamily	Aspartic peptidase domain superfamily	Interproscan
IPR001969	Active_site	Aspartic peptidase, active site	Interproscan
IPR033121	Domain	Peptidase family A1 domain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR47965	ASPARTYL PROTEASE-RELATED	Interproscan

Gene Ontology

GO terms	Category	Description	Source
GO:0004190	Molecular Function	aspartic-type endopeptidase activity	Interproscan
GO:0006508	Biological Process	proteolysis	Interproscan
GO:0005768	Cellular Component	endosome	Interproscan
GO:0005802	Cellular Component	trans-Golgi network	Interproscan
GO:0005886	Cellular Component	plasma membrane	Interproscan
GO:0006509	Biological Process	membrane protein ectodomain proteolysis	Interproscan
GO:0050435	Biological Process	amyloid-beta metabolic process	Interproscan

KEGG pathway

KO	Enzyme	Enzyme ID	pathway	mapID	Source
K07747	BACE2; beta-site APP-cleaving enzyme 2 (memapsin 1)	EC:3.4.23.45	Peptidases and inhibitors	ko01002	deepkoala