Genomic Location: sc0000065_pilon:249737...269715
NR annotation: XP_044180592.1, guanine nucleotide exchange factor DBS-like isoform X3 [Acropora millepora]
| CDS | |||||
| aawi_s0065.g26.t3 | |||||
| Transcript |
| aawi_s0065.g26.t3 |
| Protein |
| aawi_s0065.g26.t3 |
| Uniprot term | Description | ||||
|---|---|---|---|---|---|
| Q63406 | Guanine nucleotide exchange factor DBS OS=Rattus norvegicus OX=10116 GN=Mcf2l PE=1 SV=3 | ||||
| O15068 | Guanine nucleotide exchange factor DBS OS=Homo sapiens OX=9606 GN=MCF2L PE=1 SV=2 | ||||
| Q64096 | Guanine nucleotide exchange factor DBS OS=Mus musculus OX=10090 GN=Mcf2l PE=1 SV=2 |
| Gene family | Subfamily |
|---|---|
| Ubiquitin Family | UBD|Other|SH3 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF13716 | CRAL_TRIO_2 | Divergent CRAL/TRIO domain | Domain | Interproscan |
| PF00018 | SH3_1 | SH3 domain | Domain | Interproscan |
| PF00621 | RhoGEF | RhoGEF domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR001452 | Domain | SH3 domain | Interproscan |
| IPR018159 | Repeat | Spectrin/alpha-actinin | Interproscan |
| IPR000219 | Domain | Dbl homology (DH) domain | Interproscan |
| IPR011993 | Homologous_superfamily | PH-like domain superfamily | Interproscan |
| IPR001251 | Domain | CRAL-TRIO lipid binding domain | Interproscan |
| IPR001849 | Domain | Pleckstrin homology domain | Interproscan |
| IPR036028 | Homologous_superfamily | SH3-like domain superfamily | Interproscan |
| IPR051336 | Family | Rho GTPase-activating Guanine Nucleotide Exchange Factors | Interproscan |
| IPR035899 | Homologous_superfamily | Dbl homology (DH) domain superfamily | Interproscan |
| IPR001331 | Conserved_site | Guanine-nucleotide dissociation stimulator, CDC24, conserved site | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR22826 | RHO GUANINE EXCHANGE FACTOR-RELATED | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0005085 | Molecular Function | guanyl-nucleotide exchange factor activity | Interproscan |
| GO:0005737 | Cellular Component | cytoplasm | Interproscan |
| GO:0035556 | Biological Process | intracellular signal transduction | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K20685 | MCF2, ARHGEF14_21_22; guanine nucleotide exchange factor MCF2 | - | Membrane trafficking | ko04131 | deepkoala |
Maintained by Dr. Jiajie She from Prof. Longjun Wu's Lab & Prof. Pei-yuan Qian's Lab
Hong Kong Branch of the Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou)
Hong Kong University of Science and Technology
Clear Water Bay, Kowloon, Hong Kong
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