Gene detail

Detailed information of acyt_s0019.g78.t1 in Acropora cytherea

Genomic Location: sc0000019_pilon:1687906...1730768
NR annotation: XP_044165791.1, DENN domain-containing protein 3-like [Acropora millepora]
Species Acropora cytherea · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

acyt_s0019.g78.t1

ATGTGTAACAGTTTGATTGAGATCTGTGCAGTGGTTGGCATGGATCAGGATACAGGCCTAATACCATCATCCTTATCACCTAAGCAAAGAAATGTATCCAGCAGCAATCACTCCTATCTTTTTTCCACAATGTTTGAGACCAGTGTTTTGGCACAAGTATCAGGTGAAACAGCCTCATTCCCTCAAACTCCATGTGAAGTCAATGGTGAACCATTTTATCCCAAGTATGGTGTAGTGAGTAGCCCGGTCAAAAGGGGAGCAAAAGGTAGACGTGGATCACTAATACATGTACACGGTGGACCCAAGCCAGCAGACTTGCCGTTACCACAAGAGGTCATCAGCAACCTGCCTGCACTTTGCTTTCCTGATGGCGCGTTTGTTTCTAAGAAAAGAAAGCCTGTTTCCTGTCATTCGATGGTTTTTACAGATATTGAGGGCAATCACACCTATTGTATGTCGATGACGTTTTTCAGAGGGTTTCTTCTCAAGGAGTCAGAAGACGATCGCTCCCTTGGCAAATATGAATTGTTCTTTATGGATGAGGATGCAGATGAAAGAACTATGCAGGATTCTTCCTATGCGGTTTGCTATGTTCCAACTTGCTGTTGTCTGATTTCCAAAAAGCCTTACTTTAATCTGATGAAGGACTGCCTGTCCTGCTTATTGCCGCAAGTGTTAAGAAGCGATGCACGCAGCTTCAGATTAGCTCTAATGCGGTTTGTATCACAGCTGGCCATGGTACCAATCCCACCTGCAGGCTCACTTGGAATAGAGTTCGAGCTCTGTGGCATCAGGCATTTAGTCCGTCCTGCTGAAAACCCGGAAACCAGATTGATAGACATGGAGCTTCATTATCCGTTTCTTTACTTCTCTTTGGATGACATTCTGTTGCTGATCAGCTGTATATTGACACAACAGAGAATTGTTTTTCTTTCCTCGTCTTATTCTCTTCTTACTCCTATCATCGAGAGCTTTTTTACGTTTATCCAACCATTTTCCTGGAGTTTCACTTATGTTCCGATCCTTCCAAGCAACCTTCTTGATTTAGTGGACGCCCCAGGTGTGTTTATCATGGGTTGTCATGCCCAACACAAGCATCAGATTCATAGGTTTGTCACCGAGGTGGACGAGGTCTCCAGTATAGTAATCGCAGACATTGACGAAGGGCAAGTTATGATTCATCGAGATGCAAAAATTCCGCGGCTACCCACTTATGCCACAGACATGTTCAAATTCAGAATGAAGAACGCAGAAATTGATTTTGAGCGAGTCCTTGCTGAAAGACAAACATTTTTCAATGTAGAAGAACTTCAACAGGAACGAGTAAAATTTGTCAGAAAGTTTCAACAGCTGGTTTTAGCCTCTGCACAGGAAATGATACTCCGAATGTTTAGCAACATAAAAGACGTCGTTGTCCAGCGTGAAGAAGATCTTTTTTTTGACATGGAGAACTTCATCGAGTCAAAGCCGTTCGACGACAAAGAGTTCTACAAAGAGGTCTGCCAGAGCCACTCCTTCAGCGCGTTCCTTCGTGACCTGATACGTGACCTGGATGTCATGGCTCAAAAAGTAGGAGTAGTACCCAAGTTGCCATCTACGAGGAAAAGAAGTTCTACAACTGTTTCTGTGCATGTACCGGTCATTGCAGACCAGTTTTTTCAGAATCCACAGGCAGATTTAAGCATTTACGTTCTTCCACCATTTGGCCAAGAAGGGATTTACTCAGGGCGTTTCTATGGAGTGTACTCGAAATCTCTGGATGAAAAAATCTCGGATCTTATGGCCAAGTCTTCGAGTTTGGTAGCCAACTATTTGTATTTGCGTGGAATGCTGAGAGCTTCTTGTGGTGAGAATCTAGAGGCAATAGATGATTTCTTTTTGGTATCTTCGAGAAATGTCCAGCTCTTTCCAAAGAAGATTGTGCAAGAAATTTTGTGTAAACTGAAAGACGCAGAATTAGAGAAGTTAAGAACGCGGCAGTATTGGAGGAAAGCGGAGACTTTAAGAATGCAGGCTGAGGAAAAGCAAGATTTCAGAAGAGATAGAAAAGAGGTCCTTACGTCAGCTATACCGTCCGCCCCTTTGACTCTTTCAGAGTTTGTGAAACATGTCAGCAGGCTACAAATTGCCGACAGTCGCGATGCAGGAAAAAGATTGTTTCATGCTCTAACATTCAGTTCCAAAGTGGAAGCTGTTGAGCCTGAAGCATTCGCTGCATTTTATGAAGCCTACACTATGGCTACCAGCGAGGCCACAAGCTTCTCACTGCGTAACATTCGCTTAGAAGAAGATGAGGACATTTTGAAGATCTCAAAGCTCATCAGAACAGACCGTGGAATGGGATTCCTGGTTTTGTCTAAATATAGATTGTTTTTGTTGGAAAATGGAACGCAGAGTTGTGACACCATCATCAGTGTTAAGGATATCAGGAACGTTGAGATTATTTTCCCAACGCGGCTGTTGCGTAGGACAGCATCGATTCAAGTAACCAGCGAAAGTAAGCCGTCATTCTCCTTTGTAGCTTGGATAACAGGTGAAAACGAATTCTGGCGAGATTGTTTATTGGAAATGAAAGCTGGATACAGTATGGCTTGTGGCTTTAAGGACCTGGCCATAATCGGTCATGCTGCTAAGAATGTGATAATAGCAGATGTGCTAAGACAGTGTGATTTTCCAGAGGAAAGTGTATCGCTTGTGTTTTGCTTCAGCACTCAAAAGGATTCAAATAATCAACTGTCTGATCACACCAGAAAGACACTTTTAAAGAGAGTCACTCTACCACTTCAAGACATAGAGAAAGCAACAGTGGAGTCTCTTATCTACTTGCCTGCGTCTAAAGACAGCTCTGAAAAGGTGTGGTGTGCTATGGGCTCGTCTGGTGTAATTGTTGTAATCGATGGGGTTGCCTTGGAATATGAAAAGCACATGAGTTACGCGAAAGAAAGAGTGACTTGCTTGCTAACGGTTGGACAGCATCATGTTTGGGCTGGATGTTTGGATAACACCATATATGTCGTTGATATTCTCACTGGGGAAGCTGATCAGCAGCTGTCTGGTCACAGGGACTCCTTGTCGCATATGCTGCAAACCGAAGATGAAAGAGGAGTTAACACTGTGTGGAGTGCAAGTTCAAACGGACAGATTGTAGGTTGGGATCCTGTTACTCTAACGGCCAAGAAAGAACTTCAGGTAAAACTAGGAAGGAGGGATGAAAAGACTTTGCATTGGTTTTGTGCTGTGGGGAGAACGTTTTGGTGCGCAACAAGGTTTTCAGTTTACGTGTTAGATTATGTGAGAGATAAAGAAGGCACCAAAGTGTTGACTCCCATGCAAGATAAGCAGATGAGCATCGACTGCGCGTGCGTTGTGTCCACGTTTGAGGTTTGGGTTGCATGTGATAAGCGTGCTCACATTGTCACTTGGAACACTGCAACCTACGAAAAGAAAGAGCGCAGGCTTTACAAGTGTAAAGATTGCTCAATAAGCAAATGTGGTGGATTTACGAAAATGATGGAAGTTGGTAACCAGGTTTGGGTTGGAAGCAAGAGTGGCACGATCTATGTCATGAGCAAAACATTGGATCTGGAGATGGAGCTGAGTTTACACGAGGATCGAATTCGTGCCATGTGCATAACAGACTATGGCTTGGTCATCACGGGCCCCGGGTCGCGGGACGGAAGAATTGCCGTTTGGAAGTCCAACCTCGCTGAATACTCTGCGCCGAAAGTGGTCAAAGTAGATACTGCTCCTTGTGAGGTAGATGGTTTTCAAATGATTTGCAGAACGAGCTCCCTCAGTTCGACTTGA

Transcript

acyt_s0019.g78.t1

CGCAATCCAAAGAAGGTTACCTTTCCCGAAATGGTGACCTATAATTTCCTTGAAGAGTAGACTTCCGTTTTCAATTTTAAAGACTTTTATTTTGTAGATGATACACAACAGCTAAAGAGAAAATAGTAAAGGATGGAAAATCATTTTAAGAAAATGTGTAACAGTTTGATTGAGATCTGTGCAGTGGTTGGCATGGATCAGGATACAGGCCTAATACCATCATCCTTATCACCTAAGCAAAGAAATGTATCCAGCAGCAATCACTCCTATCTTTTTTCCACAATGTTTGAGACCAGTGTTTTGGCACAAGTATCAGGTGAAACAGCCTCATTCCCTCAAACTCCATGTGAAGTCAATGGTGAACCATTTTATCCCAAGTATGGTGTAGTGAGTAGCCCGGTCAAAAGGGGAGCAAAAGGTAGACGTGGATCACTAATACATGTACACGGTGGACCCAAGCCAGCAGACTTGCCGTTACCACAAGAGGTCATCAGCAACCTGCCTGCACTTTGCTTTCCTGATGGCGCGTTTGTTTCTAAGAAAAGAAAGCCTGTTTCCTGTCATTCGATGGTTTTTACAGATATTGAGGGCAATCACACCTATTGTATGTCGATGACGTTTTTCAGAGGGTTTCTTCTCAAGGAGTCAGAAGACGATCGCTCCCTTGGCAAATATGAATTGTTCTTTATGGATGAGGATGCAGATGAAAGAACTATGCAGGATTCTTCCTATGCGGTTTGCTATGTTCCAACTTGCTGTTGTCTGATTTCCAAAAAGCCTTACTTTAATCTGATGAAGGACTGCCTGTCCTGCTTATTGCCGCAAGTGTTAAGAAGCGATGCACGCAGCTTCAGATTAGCTCTAATGCGGTTTGTATCACAGCTGGCCATGGTACCAATCCCACCTGCAGGCTCACTTGGAATAGAGTTCGAGCTCTGTGGCATCAGGCATTTAGTCCGTCCTGCTGAAAACCCGGAAACCAGATTGATAGACATGGAGCTTCATTATCCGTTTCTTTACTTCTCTTTGGATGACATTCTGTTGCTGATCAGCTGTATATTGACACAACAGAGAATTGTTTTTCTTTCCTCGTCTTATTCTCTTCTTACTCCTATCATCGAGAGCTTTTTTACGTTTATCCAACCATTTTCCTGGAGTTTCACTTATGTTCCGATCCTTCCAAGCAACCTTCTTGATTTAGTGGACGCCCCAGGTGTGTTTATCATGGGTTGTCATGCCCAACACAAGCATCAGATTCATAGGTTTGTCACCGAGGTGGACGAGGTCTCCAGTATAGTAATCGCAGACATTGACGAAGGGCAAGTTATGATTCATCGAGATGCAAAAATTCCGCGGCTACCCACTTATGCCACAGACATGTTCAAATTCAGAATGAAGAACGCAGAAATTGATTTTGAGCGAGTCCTTGCTGAAAGACAAACATTTTTCAATGTAGAAGAACTTCAACAGGAACGAGTAAAATTTGTCAGAAAGTTTCAACAGCTGGTTTTAGCCTCTGCACAGGAAATGATACTCCGAATGTTTAGCAACATAAAAGACGTCGTTGTCCAGCGTGAAGAAGATCTTTTTTTTGACATGGAGAACTTCATCGAGTCAAAGCCGTTCGACGACAAAGAGTTCTACAAAGAGGTCTGCCAGAGCCACTCCTTCAGCGCGTTCCTTCGTGACCTGATACGTGACCTGGATGTCATGGCTCAAAAAGTAGGAGTAGTACCCAAGTTGCCATCTACGAGGAAAAGAAGTTCTACAACTGTTTCTGTGCATGTACCGGTCATTGCAGACCAGTTTTTTCAGAATCCACAGGCAGATTTAAGCATTTACGTTCTTCCACCATTTGGCCAAGAAGGGATTTACTCAGGGCGTTTCTATGGAGTGTACTCGAAATCTCTGGATGAAAAAATCTCGGATCTTATGGCCAAGTCTTCGAGTTTGGTAGCCAACTATTTGTATTTGCGTGGAATGCTGAGAGCTTCTTGTGGTGAGAATCTAGAGGCAATAGATGATTTCTTTTTGGTATCTTCGAGAAATGTCCAGCTCTTTCCAAAGAAGATTGTGCAAGAAATTTTGTGTAAACTGAAAGACGCAGAATTAGAGAAGTTAAGAACGCGGCAGTATTGGAGGAAAGCGGAGACTTTAAGAATGCAGGCTGAGGAAAAGCAAGATTTCAGAAGAGATAGAAAAGAGGTCCTTACGTCAGCTATACCGTCCGCCCCTTTGACTCTTTCAGAGTTTGTGAAACATGTCAGCAGGCTACAAATTGCCGACAGTCGCGATGCAGGAAAAAGATTGTTTCATGCTCTAACATTCAGTTCCAAAGTGGAAGCTGTTGAGCCTGAAGCATTCGCTGCATTTTATGAAGCCTACACTATGGCTACCAGCGAGGCCACAAGCTTCTCACTGCGTAACATTCGCTTAGAAGAAGATGAGGACATTTTGAAGATCTCAAAGCTCATCAGAACAGACCGTGGAATGGGATTCCTGGTTTTGTCTAAATATAGATTGTTTTTGTTGGAAAATGGAACGCAGAGTTGTGACACCATCATCAGTGTTAAGGATATCAGGAACGTTGAGATTATTTTCCCAACGCGGCTGTTGCGTAGGACAGCATCGATTCAAGTAACCAGCGAAAGTAAGCCGTCATTCTCCTTTGTAGCTTGGATAACAGGTGAAAACGAATTCTGGCGAGATTGTTTATTGGAAATGAAAGCTGGATACAGTATGGCTTGTGGCTTTAAGGACCTGGCCATAATCGGTCATGCTGCTAAGAATGTGATAATAGCAGATGTGCTAAGACAGTGTGATTTTCCAGAGGAAAGTGTATCGCTTGTGTTTTGCTTCAGCACTCAAAAGGATTCAAATAATCAACTGTCTGATCACACCAGAAAGACACTTTTAAAGAGAGTCACTCTACCACTTCAAGACATAGAGAAAGCAACAGTGGAGTCTCTTATCTACTTGCCTGCGTCTAAAGACAGCTCTGAAAAGGTGTGGTGTGCTATGGGCTCGTCTGGTGTAATTGTTGTAATCGATGGGGTTGCCTTGGAATATGAAAAGCACATGAGTTACGCGAAAGAAAGAGTGACTTGCTTGCTAACGGTTGGACAGCATCATGTTTGGGCTGGATGTTTGGATAACACCATATATGTCGTTGATATTCTCACTGGGGAAGCTGATCAGCAGCTGTCTGGTCACAGGGACTCCTTGTCGCATATGCTGCAAACCGAAGATGAAAGAGGAGTTAACACTGTGTGGAGTGCAAGTTCAAACGGACAGATTGTAGGTTGGGATCCTGTTACTCTAACGGCCAAGAAAGAACTTCAGGTAAAACTAGGAAGGAGGGATGAAAAGACTTTGCATTGGTTTTGTGCTGTGGGGAGAACGTTTTGGTGCGCAACAAGGTTTTCAGTTTACGTGTTAGATTATGTGAGAGATAAAGAAGGCACCAAAGTGTTGACTCCCATGCAAGATAAGCAGATGAGCATCGACTGCGCGTGCGTTGTGTCCACGTTTGAGGTTTGGGTTGCATGTGATAAGCGTGCTCACATTGTCACTTGGAACACTGCAACCTACGAAAAGAAAGAGCGCAGGCTTTACAAGTGTAAAGATTGCTCAATAAGCAAATGTGGTGGATTTACGAAAATGATGGAAGTTGGTAACCAGGTTTGGGTTGGAAGCAAGAGTGGCACGATCTATGTCATGAGCAAAACATTGGATCTGGAGATGGAGCTGAGTTTACACGAGGATCGAATTCGTGCCATGTGCATAACAGACTATGGCTTGGTCATCACGGGCCCCGGGTCGCGGGACGGAAGAATTGCCGTTTGGAAGTCCAACCTCGCTGAATACTCTGCGCCGAAAGTGGTCAAAGTAGATACTGCTCCTTGTGAGGTAGATGGTTTTCAAATGATTTGCAGAACGAGCTCCCTCAGTTCGACTTGAAACACACCCAAGCTAGTTTTATCTAACACTCTCCTCGTTGACAATTCTACAAAAATGTCGCTGTTTTTATTTCATTTTTAATTTTTCTATGAAGTTAAACTAGTATGTAGACTGGATATGGACAAATTAAGCGCATGCGCAGGTTTCTTCGCAGCCGTCAGCAATTTTTGGTGGCATTCCAAAACGGGCGGTAAACTACAGCTAGTTTAGAAAACCAAAGACCATAAGGAGGCAGGACTGGTTATCGGTAAGATCTTTTTGGGAATATTAGGATGTTTGCTGGCTCATGTAAAGAGAAATGAACCCAGTACCTGTACAATTGGGTCGGAAGTCTCGATTTCGAAAGTGTTGGGTTTTTCAAGATAGTAGTGCCTAATAAGGACATTTTTTGTCAGAATTTTTCACTCTCTCCAACCAGTGCCGCACATAATTGTATAAATGAAAAAGTATATACATATAATATACGACAAAATAAAGAAAAATCCTGGTAACGTGTTATCCCTAACAACAGCGCACCAATTTCTAAGAAATGTTTAGGTGGACGAATCCAGTCTGTTATCTTCTGTGAGTTGCAAATCACAGCAAACAAGGCCGTTTTACCAAATCCCCTTGGCAAATCCTCTAGCCAAGGCTCTGCTTCCTAAAAGATGATGACTTTTCCAAGCACATGCTTTCTCGACACTGGAATAAGTTTAATCATGTAATGAAGAGAATCAATACAAGCTCGCACAGGAGTGATGTCATTAAGGTTAAAGAGGGACATTGATACGAACATTATGCCGGTTCTAGGTCAAAACTGACAACACTTTACTGGGAAATGTCGCCTGTGACATGTGACTTTTTGTAGCTTTGTGTACAGAATGAGATTTTATCCTTATATTTATATATTATCACAGAAGTGTTTTTGTTATTTGTACCATTTAATAAACTCGGGTGCGTCTT

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
A2RUS2	DENN domain-containing protein 3 OS=Homo sapiens OX=9606 GN=DENND3 PE=1 SV=2
A2RT67	DENN domain-containing protein 3 OS=Mus musculus OX=10090 GN=Dennd3 PE=1 SV=2
Q6NTN5	Myotubularin-related protein 13 OS=Xenopus laevis OX=8355 GN=sbf2 PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0002252 (this species only) · gene tree & orthology
Ubiquitin family	UBD\|Other\|Beta-prp · all ubiquitin genes in this species
Ubiquitin family	E3\|E3 adaptor Cullin RING\|DWD · all ubiquitin genes in this species

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF03456 all species →	uDENN	uDENN domain	Domain	Interproscan
PF02141 all species →	DENN	DENN (AEX-3) domain	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR043153 all species →	Homologous_superfamily	DENN domain, C-terminal lobe	Interproscan
IPR015943 all species →	Homologous_superfamily	WD40/YVTN repeat-like-containing domain superfamily	Interproscan
IPR036322 all species →	Homologous_superfamily	WD40-repeat-containing domain superfamily	Interproscan
IPR005113 all species →	Domain	uDENN domain	Interproscan
IPR051696 all species →	Family	DENN Domain-Containing GEFs	Interproscan
IPR001194 all species →	Domain	cDENN domain	Interproscan
IPR037516 all species →	Domain	Tripartite DENN domain	Interproscan
IPR001680 all species →	Repeat	WD40 repeat	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR12296 all species →	DENN DOMAIN-CONTAINING PROTEIN 4	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005515 all species →	Molecular Function	protein binding	Interproscan
GO:0031410 all species →	Cellular Component	cytoplasmic vesicle	Interproscan
GO:0032483 all species →	Biological Process	regulation of Rab protein signal transduction	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K20162	DENND3; DENN domain-containing protein 3	-	Membrane trafficking	ko04131	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Acropora cytherea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Acropora cytherea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →