Gene detail

Detailed information of acyt_s0036.g52.t1 in Acropora cytherea

Genomic Location: sc0000036_pilon:930329...934839
NR annotation: XP_029196859.2, transmembrane prolyl 4-hydroxylase-like [Acropora millepora]

Gene Structure

Sequence

Uniprot

Uniprot term	Description
Q9NXG6	Transmembrane prolyl 4-hydroxylase OS=Homo sapiens OX=9606 GN=P4HTM PE=1 SV=2
Q8BG58	Transmembrane prolyl 4-hydroxylase OS=Mus musculus OX=10090 GN=P4htm PE=1 SV=1
F4JNU8	Probable prolyl 4-hydroxylase 8 OS=Arabidopsis thaliana OX=3702 GN=P4H8 PE=3 SV=1

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF13640	2OG-FeII_Oxy_3	2OG-Fe(II) oxygenase superfamily	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR011992	Homologous_superfamily	EF-hand domain pair	Interproscan
IPR045054	Family	Prolyl 4-hydroxylase	Interproscan
IPR044862	Domain	Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain	Interproscan
IPR002048	Domain	EF-hand domain	Interproscan
IPR018247	Binding_site	EF-Hand 1, calcium-binding site	Interproscan
IPR006620	Domain	Prolyl 4-hydroxylase, alpha subunit	Interproscan
IPR005123	Domain	Oxoglutarate/iron-dependent dioxygenase	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR10869	PROLYL 4-HYDROXYLASE ALPHA SUBUNIT	Interproscan

Gene Ontology

GO terms	Category	Description	Source
GO:0004656	Molecular Function	procollagen-proline 4-dioxygenase activity	Interproscan
GO:0005783	Cellular Component	endoplasmic reticulum	Interproscan
GO:0018401	Biological Process	peptidyl-proline hydroxylation to 4-hydroxy-L-proline	Interproscan
GO:0005509	Molecular Function	calcium ion binding	Interproscan
GO:0005506	Molecular Function	iron ion binding	Interproscan
GO:0016705	Molecular Function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	Interproscan
GO:0031418	Molecular Function	L-ascorbic acid binding	Interproscan

KEGG pathway

KO	Enzyme	Enzyme ID	pathway	mapID	Source
K06711	PH-4; hypoxia-inducible factor prolyl 4-hydroxylase	EC:1.14.11.-	Domain-containing proteins not elsewhere classified	ko04990	deepkoala