Genomic Location: sc0000011_pilon:1019235...1031045
NR annotation: XP_029204531.2, RING-type E3 ubiquitin-protein ligase PPIL2-like [Acropora millepora]
Species Acropora echinata · all data for this species · gene families
| CDS |
| aech_s0011.g125.t1 |
| Transcript |
| aech_s0011.g125.t1 |
| Protein |
| aech_s0011.g125.t1 |
| UniProt accession | Description |
|---|---|
| Q9D787 | RING-type E3 ubiquitin-protein ligase PPIL2 OS=Mus musculus OX=10090 GN=Ppil2 PE=1 SV=2 |
| Q13356 | RING-type E3 ubiquitin-protein ligase PPIL2 OS=Homo sapiens OX=9606 GN=PPIL2 PE=1 SV=1 |
| P52012 | Peptidyl-prolyl cis-trans isomerase 4 OS=Caenorhabditis elegans OX=6239 GN=cyn-4 PE=1 SV=3 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0005144 (this species only) · gene tree & orthology |
| Ubiquitin family | E3|E3 activity RING|U-box · all ubiquitin genes in this species |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF04641 all species → | Rtf2 | Rtf2 RING-finger | Family | Interproscan |
| PF00160 all species → | Pro_isomerase | Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR003613 all species → | Domain | U-box domain | Interproscan |
| IPR013083 all species → | Homologous_superfamily | Zinc finger, RING/FYVE/PHD-type | Interproscan |
| IPR002130 all species → | Domain | Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain | Interproscan |
| IPR020892 all species → | Conserved_site | Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site | Interproscan |
| IPR026951 all species → | Domain | Peptidyl-prolyl cis-trans isomerase like 2, U-box domain | Interproscan |
| IPR029000 all species → | Homologous_superfamily | Cyclophilin-like domain superfamily | Interproscan |
| IPR044666 all species → | Family | Cyclophilin-type peptidyl-prolyl cis-trans isomerase, cyclophilin A-like | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR45625 all species → | PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0004842 all species → | Molecular Function | ubiquitin-protein transferase activity | Interproscan |
| GO:0016567 all species → | Biological Process | protein ubiquitination | Interproscan |
| GO:0000413 all species → | Biological Process | protein peptidyl-prolyl isomerization | Interproscan |
| GO:0003755 all species → | Molecular Function | peptidyl-prolyl cis-trans isomerase activity | Interproscan |
| GO:0006457 all species → | Biological Process | protein folding | Interproscan |
| GO:0000209 all species → | Biological Process | protein polyubiquitination | Interproscan |
| GO:0061630 all species → | Molecular Function | ubiquitin protein ligase activity | Interproscan |
| GO:0071013 all species → | Cellular Component | catalytic step 2 spliceosome | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K10598 | PPIL2, CYC4, CHP60; peptidyl-prolyl cis-trans isomerase-like 2 | EC:5.2.1.8 | Ubiquitin system | ko04121 | deepkoala |
Genes whose expression across the transcriptome samples of Acropora echinata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Acropora echinata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
