Genomic Location: sc0000014_pilon:2959462...2991031
NR annotation: XP_029185794.2, inactive histone-lysine N-methyltransferase 2E-like [Acropora millepora]
Species Acropora echinata · all data for this species · gene families
| CDS |
| aech_s0014.g224.t1 |
| Transcript |
| aech_s0014.g224.t1 |
| Protein |
| aech_s0014.g224.t1 |
| UniProt accession | Description |
|---|---|
| Q3UG20 | Inactive histone-lysine N-methyltransferase 2E OS=Mus musculus OX=10090 GN=Kmt2e PE=1 SV=2 |
| Q8IZD2 | Inactive histone-lysine N-methyltransferase 2E OS=Homo sapiens OX=9606 GN=KMT2E PE=1 SV=1 |
| Q5XJV7 | Histone-lysine N-methyltransferase SETD5 OS=Mus musculus OX=10090 GN=Setd5 PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0003565 (this species only) · gene tree & orthology |
| Ubiquitin family | E3|E3 activity RING|PHD · all ubiquitin genes in this species |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF20826 all species → | PHD_5 | PhD finger domain | Domain | Interproscan |
| PF00856 all species → | SET | SET domain | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR046341 all species → | Homologous_superfamily | SET domain superfamily | Interproscan |
| IPR011011 all species → | Homologous_superfamily | Zinc finger, FYVE/PHD-type | Interproscan |
| IPR013083 all species → | Homologous_superfamily | Zinc finger, RING/FYVE/PHD-type | Interproscan |
| IPR001214 all species → | Domain | SET domain | Interproscan |
| IPR019786 all species → | Conserved_site | Zinc finger, PHD-type, conserved site | Interproscan |
| IPR001965 all species → | Domain | Zinc finger, PHD-type | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR46462 all species → | UPSET, ISOFORM A | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0006355 all species → | Biological Process | regulation of DNA-templated transcription | Interproscan |
| GO:0034967 all species → | Cellular Component | Set3 complex | Interproscan |
| GO:0035064 all species → | Molecular Function | methylated histone binding | Interproscan |
| GO:0070210 all species → | Cellular Component | Rpd3L-Expanded complex | Interproscan |
| GO:0005515 all species → | Molecular Function | protein binding | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K09189 | MLL5; [histone H3]-lysine4 N-trimethyltransferase MLL5 | EC:2.1.1.354 | Chromosome and associated proteins | ko03036 | deepkoala |
Genes whose expression across the transcriptome samples of Acropora echinata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Acropora echinata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |