Genomic Location: sc0000033_pilon:1597521...1617117
NR annotation: UCR73890.1, IKKa/b [Acropora cervicornis]
| CDS | |||||
| aech_s0033.g63.t1 | |||||
| Transcript |
| aech_s0033.g63.t1 |
| Protein |
| aech_s0033.g63.t1 |
| Uniprot term | Description | ||||
|---|---|---|---|---|---|
| O15111 | Inhibitor of nuclear factor kappa-B kinase subunit alpha OS=Homo sapiens OX=9606 GN=CHUK PE=1 SV=2 | ||||
| Q95KV1 | Inhibitor of nuclear factor kappa-B kinase subunit alpha OS=Bos taurus OX=9913 GN=CHUK PE=1 SV=1 | ||||
| Q28DZ1 | Inhibitor of nuclear factor kappa-B kinase subunit alpha OS=Xenopus tropicalis OX=8364 GN=chuk PE=2 SV=1 |
| Gene family | Subfamily |
|---|---|
| Ubiquitin Family | ULD|UFD/UBQ|UBQ_Other |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00069 | Pkinase | Protein kinase domain | Domain | Interproscan |
| PF18397 | IKBKB_SDD | IQBAL scaffold dimerization domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR000626 | Domain | Ubiquitin-like domain | Interproscan |
| IPR008271 | Active_site | Serine/threonine-protein kinase, active site | Interproscan |
| IPR051180 | Family | Inhibitor of nuclear factor kappa-B kinase | Interproscan |
| IPR017441 | Binding_site | Protein kinase, ATP binding site | Interproscan |
| IPR046375 | Homologous_superfamily | IKBKB, scaffold dimerization domain superfamily | Interproscan |
| IPR000719 | Domain | Protein kinase domain | Interproscan |
| IPR029071 | Homologous_superfamily | Ubiquitin-like domain superfamily | Interproscan |
| IPR011009 | Homologous_superfamily | Protein kinase-like domain superfamily | Interproscan |
| IPR041185 | Domain | IKBKB, scaffold dimerization domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR22969 | IKB KINASE | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0004672 | Molecular Function | protein kinase activity | Interproscan |
| GO:0006468 | Biological Process | protein phosphorylation | Interproscan |
| GO:0004674 | Molecular Function | protein serine/threonine kinase activity | Interproscan |
| GO:0005737 | Cellular Component | cytoplasm | Interproscan |
| GO:0008384 | Molecular Function | IkappaB kinase activity | Interproscan |
| GO:0008385 | Cellular Component | IkappaB kinase complex | Interproscan |
| GO:0018105 | Biological Process | peptidyl-serine phosphorylation | Interproscan |
| GO:0033209 | Biological Process | tumor necrosis factor-mediated signaling pathway | Interproscan |
| GO:0045944 | Biological Process | positive regulation of transcription by RNA polymerase II | Interproscan |
| GO:0051092 | Biological Process | positive regulation of NF-kappaB transcription factor activity | Interproscan |
| GO:0005524 | Molecular Function | ATP binding | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K04467 | IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha | EC:2.7.11.10 | Protein kinases | ko01001 | deepkoala |