Gene detail

Detailed information of aech_s0033.g63.t2 in Acropora echinata

Genomic Location: sc0000033_pilon:1597521...1617117
NR annotation: XP_029198688.2, inhibitor of nuclear factor kappa-B kinase subunit beta-like isoform X2 [Acropora millepora]
Species Acropora echinata · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

aech_s0033.g63.t2

ATGGAATATGGAAGGGCAATTAACCTATCAAGGGAGGGTTGGATGGAAGAAAGATGCCTTGGAGCTGGTGGATTTGGAACTGTAATGTTATATGAAAATAAGATTACAAAGGAACAAGTTGCTCTGAAAAGGTGTCGTTTGGAACTGAATTCCCATAACAGAAAGCGTTGGCAACAAGAGGTAGAGATCATGAAGAGGCTCCATCACCCTAACCTTGTGTCTGCTAGAGATGTACCTCCAGCTCTGGATGTCAGTGATGATGAGCTTCCCTTGTTGGCAATGGAATTCTGTTCTGGTGGAGATTTGAGAAAGGTTCTGAATGCTCCAGAGAGTTGCTGTGGCCTGAAGGAAACGACAGTCCTTCAAATTGCTGGTGATGTCGCTGCAGCTGTGGAGTTTCTTCATAGCCACCGCATCATTCACAGAGATCTTAAACCTGAAAATATTGTGATTAACCATGTTGATAGAAAGGTTATCTACAAACTTATCGATCTTGGTTATGCAAAAGAACTGGATCAAGCAAGTATGGCTACAACATTTGTGGGAACCCTGAAGTATTTGGCTCCTGAACTACTTGACAGAGTTGAATATACAAAATCAGTTGATTATTGGAGTTTTGGCACAGTTCTATTTGAATGCATTACTGGTGTGAGGCCTTTCCTCCCAGAACTTTCTCCAGTGAAATGGCACAATGTGGTTTTCAAAAAAGGTGCAGATGATATTTGTGCCTTCTTTGATGTAAAAGGAGAGGTTCAATTTTCATCGATTTTGCCAGTTCCCAATACTCTCTGCAGACAACTTCAAGATAAGTTTGTTAGTCTGCTAAGACTACTTTTGCTTTGGGACCCAAAAAGGCGGGGAGGCCTTGTGCTTGATAATGGAAAGAGAGAGTGTTTCGACATGCTGGAAAAGATTGTCAATACTGTGGTTGTTCATGTGTTTCCAATAGCAACAGCAACTTTAATCTCATTTGAAGTTTTCCCAAGTGAAACAGTTGATGATTTAAAAGTGAAGTTGTCTGAGGCAACTGGTGTGAAGGAAGAGCATGAATTATTGACAGTGTCGGGGCAACTTCTTGAGTCAAACGGTCTTGTCATGGACATCTGCAATAGAGATAGCAAGTTTGAAGGAGACTGTCTTTTGTATCTTATATCCACGGGGAACGGATCTCTATCACCACCGCCAATTTTTGCCTTGCCTGGCACGGTGCATGGAATGGTCACTGAGCCTAAAACTCTGATGTCTTACGAGGATCTGAAGAAGGCTTTTGCTGTTGGAGTGAATTTCTGTTGGGAACAGAGAAGGATAAATCTCTTGTTAATTGAAGGTTTTAGGGCAGCCCAGATATCCTTGTTACATTTGAATTCAAGGCTTGGACAGATGAAAAATGATGTGACAGCAGAGCTAAAAAAACTTGAAGCCAAAGTGGATTTCTTCAATTCAAGTTTACAATTTGACTTAGAATGCTACGAAGAAAACATCAGCCTCATGAAAAATGACAAAGTATTTCGCGCATGGAAAAGAGCACAGAAAAAAGTGGCGAGTTTCCAAAACAACGATGTACTGGCATTGTTAAATTCAACGATGATTCTTCAGGGTAAGATAGTTGAGTCACAGAAGGGTCCATATGCAAGTGGAACTCAAGCAAAATCGAAAGTGGATGGGATGTATAACAATGTTTTGAAGTTATTTGAAGATTTGAGACAAGGCGATCGACGCCCAGCTGATTCTCAAAATATAGTGGCTGTAATCCTGCAATTTCTTGCTCAGAAAGAGAAACTTCACAAAGATATTCTCAGCCGTCTGAGTAAGATTATTTCTTGCAAGAGTGAGGTCCGAGAAATGATGATCAAGCTTGATAAAGCAAAATCTAAACTATTGGAAAGACAACAGGAACTTGAAGAAATGCAAAATCAAAGACAAGCTGACTTATGGAAAATACTTCAATCAATGCAGAGAGGTCAGGATAGTCGGCGCATTTCCAGTGGATCATGCACGTCTCTTTCTTCTCCGGATATTTCATGCACAGAATCCATTGTTCTTATTGAGGAGAGTTCAAGAGGTTTTGAGAAGTTTGCAGAGGTGGTTGAAAATCTAAAACTCGACCAGATCAATGAGACATTGAATCTTGACTGGGAATTCCTTGAGGAGGACAGCGGTCCTGACGACAAGAAATGGGAAGGGAGACCTGCAAGTTGA

Transcript

aech_s0033.g63.t2

CCGCAGTACTGTGAGAGAGAGGAGATTCAGAGATAAAATTATCCTAGAGGACCACAGAGAGCCAATTATCAATAATAATTTGGTGAATCAGAGAAAATTTCCATTCATTTCTACAGCCATGTAACTGGTTGGCATTCGAAGGAGTCCGAATGTTAATTTAAGGCTGTTCCACCTCATTTGGAACATTACATGAGAATTATTTTCAAAGACCTGTTTCAGAGCAACTTGTGATGGAATATGGAAGGGCAATTAACCTATCAAGGGAGGGTTGGATGGAAGAAAGATGCCTTGGAGCTGGTGGATTTGGAACTGTAATGTTATATGAAAATAAGATTACAAAGGAACAAGTTGCTCTGAAAAGGTGTCGTTTGGAACTGAATTCCCATAACAGAAAGCGTTGGCAACAAGAGGTAGAGATCATGAAGAGGCTCCATCACCCTAACCTTGTGTCTGCTAGAGATGTACCTCCAGCTCTGGATGTCAGTGATGATGAGCTTCCCTTGTTGGCAATGGAATTCTGTTCTGGTGGAGATTTGAGAAAGGTTCTGAATGCTCCAGAGAGTTGCTGTGGCCTGAAGGAAACGACAGTCCTTCAAATTGCTGGTGATGTCGCTGCAGCTGTGGAGTTTCTTCATAGCCACCGCATCATTCACAGAGATCTTAAACCTGAAAATATTGTGATTAACCATGTTGATAGAAAGGTTATCTACAAACTTATCGATCTTGGTTATGCAAAAGAACTGGATCAAGCAAGTATGGCTACAACATTTGTGGGAACCCTGAAGTATTTGGCTCCTGAACTACTTGACAGAGTTGAATATACAAAATCAGTTGATTATTGGAGTTTTGGCACAGTTCTATTTGAATGCATTACTGGTGTGAGGCCTTTCCTCCCAGAACTTTCTCCAGTGAAATGGCACAATGTGGTTTTCAAAAAAGGTGCAGATGATATTTGTGCCTTCTTTGATGTAAAAGGAGAGGTTCAATTTTCATCGATTTTGCCAGTTCCCAATACTCTCTGCAGACAACTTCAAGATAAGTTTGTTAGTCTGCTAAGACTACTTTTGCTTTGGGACCCAAAAAGGCGGGGAGGCCTTGTGCTTGATAATGGAAAGAGAGAGTGTTTCGACATGCTGGAAAAGATTGTCAATACTGTGGTTGTTCATGTGTTTCCAATAGCAACAGCAACTTTAATCTCATTTGAAGTTTTCCCAAGTGAAACAGTTGATGATTTAAAAGTGAAGTTGTCTGAGGCAACTGGTGTGAAGGAAGAGCATGAATTATTGACAGTGTCGGGGCAACTTCTTGAGTCAAACGGTCTTGTCATGGACATCTGCAATAGAGATAGCAAGTTTGAAGGAGACTGTCTTTTGTATCTTATATCCACGGGGAACGGATCTCTATCACCACCGCCAATTTTTGCCTTGCCTGGCACGGTGCATGGAATGGTCACTGAGCCTAAAACTCTGATGTCTTACGAGGATCTGAAGAAGGCTTTTGCTGTTGGAGTGAATTTCTGTTGGGAACAGAGAAGGATAAATCTCTTGTTAATTGAAGGTTTTAGGGCAGCCCAGATATCCTTGTTACATTTGAATTCAAGGCTTGGACAGATGAAAAATGATGTGACAGCAGAGCTAAAAAAACTTGAAGCCAAAGTGGATTTCTTCAATTCAAGTTTACAATTTGACTTAGAATGCTACGAAGAAAACATCAGCCTCATGAAAAATGACAAAGTATTTCGCGCATGGAAAAGAGCACAGAAAAAAGTGGCGAGTTTCCAAAACAACGATGTACTGGCATTGTTAAATTCAACGATGATTCTTCAGGGTAAGATAGTTGAGTCACAGAAGGGTCCATATGCAAGTGGAACTCAAGCAAAATCGAAAGTGGATGGGATGTATAACAATGTTTTGAAGTTATTTGAAGATTTGAGACAAGGCGATCGACGCCCAGCTGATTCTCAAAATATAGTGGCTGTAATCCTGCAATTTCTTGCTCAGAAAGAGAAACTTCACAAAGATATTCTCAGCCGTCTGAGTAAGATTATTTCTTGCAAGAGTGAGGTCCGAGAAATGATGATCAAGCTTGATAAAGCAAAATCTAAACTATTGGAAAGACAACAGGAACTTGAAGAAATGCAAAATCAAAGACAAGCTGACTTATGGAAAATACTTCAATCAATGCAGAGAGGTCAGGATAGTCGGCGCATTTCCAGTGGATCATGCACGTCTCTTTCTTCTCCGGATATTTCATGCACAGAATCCATTGTTCTTATTGAGGAGAGTTCAAGAGGTTTTGAGAAGTTTGCAGAGGTGGTTGAAAATCTAAAACTCGACCAGATCAATGAGACATTGAATCTTGACTGGGAATTCCTTGAGGAGGACAGCGGTCCTGACGACAAGAAATGGGAAGGGAGACCTGCAAGTTGAGGATATACGGTGGAAGCAGTGAGACTCTGGACTTCTTTTATATTGCATATCAGTCATTCTGACAATCTTTTCACTGAGTGGATCGATGTGGAAAAACTAGTCTACCCTTTTGGGAATGATGGCTCTATGGATATCATTCATTTATTCTAACTACTACGTTCGAACGGTTGAGCTAGTCCAAGAGCATGAAGGAATGAGTGAATCATTTTCGGAAATTGTACCTTCACGAAATATCGTCCCCATGGATTTTCCCAACTGAGCTTAAATCTTTATTGAATATACCTATAACCCTGGTAATTCTCTAGGCCACATTTGTATTTCTAATACATATATTTTTTTCATTTCCTCTGCAAGGACGTGAATTAGTTGTAACTAAAAACATACAGCTCTCCCTCAGTCCAGTTTTTAGCTGACGGTGGTCGTAGTTTCTTCACACTTTTTAGAGGTCATTTTATTTCTCTTAAGTATCAAGCTTTGCAATTCGATCTTTTAAATCCCTTAACGTCTTGTACAGAAGTATAGAATATAGCTATTTGTGCAGTGTCAGTTTATTATCCTGAACGTCAGTGCGGTATCCTTCCACCAATGCATTACCCTTTCTATAGAGAATAAAGAAACGGAAGTATGACAAAATTTAGCCGAAGTATGAAGCCCACATGGCTTTTGAGACGCAACGTTTGGACGTGGTAGTGCCTTTAAATTTGTCTCAAATGAAGACATTCGTGTACA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
O15111	Inhibitor of nuclear factor kappa-B kinase subunit alpha OS=Homo sapiens OX=9606 GN=CHUK PE=1 SV=2
O88351	Inhibitor of nuclear factor kappa-B kinase subunit beta OS=Mus musculus OX=10090 GN=Ikbkb PE=1 SV=1
Q28DZ1	Inhibitor of nuclear factor kappa-B kinase subunit alpha OS=Xenopus tropicalis OX=8364 GN=chuk PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0004442 (this species only)
Ubiquitin family	ULD\|UFD/UBQ\|UBQ_Other · all ubiquitin genes in this species

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00069 all species →	Pkinase	Protein kinase domain	Domain	Interproscan
PF18397 all species →	IKBKB_SDD	IQBAL scaffold dimerization domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR000626 all species →	Domain	Ubiquitin-like domain	Interproscan
IPR046375 all species →	Homologous_superfamily	IKBKB, scaffold dimerization domain superfamily	Interproscan
IPR000719 all species →	Domain	Protein kinase domain	Interproscan
IPR008271 all species →	Active_site	Serine/threonine-protein kinase, active site	Interproscan
IPR017441 all species →	Binding_site	Protein kinase, ATP binding site	Interproscan
IPR029071 all species →	Homologous_superfamily	Ubiquitin-like domain superfamily	Interproscan
IPR041185 all species →	Domain	IKBKB, scaffold dimerization domain	Interproscan
IPR011009 all species →	Homologous_superfamily	Protein kinase-like domain superfamily	Interproscan
IPR051180 all species →	Family	Inhibitor of nuclear factor kappa-B kinase	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR22969 all species →	IKB KINASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005515 all species →	Molecular Function	protein binding	Interproscan
GO:0004672 all species →	Molecular Function	protein kinase activity	Interproscan
GO:0005524 all species →	Molecular Function	ATP binding	Interproscan
GO:0006468 all species →	Biological Process	protein phosphorylation	Interproscan
GO:0004674 all species →	Molecular Function	protein serine/threonine kinase activity	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0008384 all species →	Molecular Function	IkappaB kinase activity	Interproscan
GO:0008385 all species →	Cellular Component	IkappaB kinase complex	Interproscan
GO:0018105 all species →	Biological Process	peptidyl-serine phosphorylation	Interproscan
GO:0033209 all species →	Biological Process	tumor necrosis factor-mediated signaling pathway	Interproscan
GO:0045944 all species →	Biological Process	positive regulation of transcription by RNA polymerase II	Interproscan
GO:0051092 all species →	Biological Process	positive regulation of NF-kappaB transcription factor activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K04467	IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha	EC:2.7.11.10	Protein kinases	ko01001	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.