Gene detail

Detailed information of aech_s0209.g16.t2 in Acropora echinata

Genomic Location: sc0000209_pilon:139846...149469
NR annotation: XP_029214426.2, NEDD8-activating enzyme E1 catalytic subunit-like isoform X1 [Acropora millepora]

Gene Structure

More details in Jbrowse

Sequence

CDS

Transcript

Protein

Uniprot

Gene family

Uniprot term	Description
Q5R4A0	NEDD8-activating enzyme E1 catalytic subunit OS=Pongo abelii OX=9601 GN=UBA3 PE=2 SV=2
Q8TBC4	NEDD8-activating enzyme E1 catalytic subunit OS=Homo sapiens OX=9606 GN=UBA3 PE=1 SV=2
Q99MI7	NEDD8-activating enzyme E1 catalytic subunit OS=Rattus norvegicus OX=10116 GN=Uba3 PE=1 SV=1

Gene family	Subfamily
Ubiquitin Family	E1\|ThiF\|ThiF

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00899	ThiF	ThiF family	Domain	Interproscan
PF08825	E2_bind	E2 binding domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR035985	Homologous_superfamily	Ubiquitin-activating enzyme	Interproscan
IPR000594	Domain	THIF-type NAD/FAD binding fold	Interproscan
IPR023318	Homologous_superfamily	Ubiquitin activating enzyme, alpha domain superfamily	Interproscan
IPR014929	Domain	E2 binding	Interproscan
IPR033127	Active_site	Ubiquitin-activating enzyme E1, Cys active site	Interproscan
IPR030468	Domain	NEDD8-activating enzyme E1 catalytic subunit, N-terminal domain	Interproscan
IPR045886	Family	ThiF/MoeB/HesA family	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR10953	UBIQUITIN-ACTIVATING ENZYME E1	Interproscan

Gene Ontology

GO terms	Category	Description	Source
GO:0008641	Molecular Function	ubiquitin-like modifier activating enzyme activity	Interproscan
GO:0019781	Molecular Function	NEDD8 activating enzyme activity	Interproscan
GO:0045116	Biological Process	protein neddylation	Interproscan
GO:0005634	Cellular Component	nucleus	Interproscan
GO:0005737	Cellular Component	cytoplasm	Interproscan
GO:0032446	Biological Process	protein modification by small protein conjugation	Interproscan

KEGG pathway

KO	Enzyme	Enzyme ID	pathway	mapID	Source
K10686	UBA3, UBE1C; NEDD8-activating enzyme E1	EC:6.2.1.64	Ubiquitin system	ko04121	deepkoala