Gene detail

Detailed information of aflo_s0018.g34.t2 in Acropora florida

Genomic Location: sc0000018_pilon:428008...435965
NR annotation: XP_029190449.2, beta-secretase 2-like isoform X1 [Acropora millepora]

Gene Structure

Sequence

Uniprot

Uniprot term	Description
W8W138	Beta-secretase OS=Strongylocentrotus purpuratus OX=7668 GN=BACE PE=2 SV=1
Q9JL18	Beta-secretase 2 OS=Mus musculus OX=10090 GN=Bace2 PE=1 SV=1
Q2HJ40	Beta-secretase 1 OS=Bos taurus OX=9913 GN=BACE1 PE=2 SV=1

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00026	Asp	Eukaryotic aspartyl protease	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR021109	Homologous_superfamily	Aspartic peptidase domain superfamily	Interproscan
IPR001969	Active_site	Aspartic peptidase, active site	Interproscan
IPR033121	Domain	Peptidase family A1 domain	Interproscan
IPR001461	Family	Aspartic peptidase A1 family	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR47965	ASPARTYL PROTEASE-RELATED	Interproscan

Gene Ontology

GO terms	Category	Description	Source
GO:0004190	Molecular Function	aspartic-type endopeptidase activity	Interproscan
GO:0006508	Biological Process	proteolysis	Interproscan
GO:0005768	Cellular Component	endosome	Interproscan
GO:0005802	Cellular Component	trans-Golgi network	Interproscan
GO:0005886	Cellular Component	plasma membrane	Interproscan
GO:0006509	Biological Process	membrane protein ectodomain proteolysis	Interproscan
GO:0050435	Biological Process	amyloid-beta metabolic process	Interproscan

KEGG pathway

KO	Enzyme	Enzyme ID	pathway	mapID	Source
K07747	BACE2; beta-site APP-cleaving enzyme 2 (memapsin 1)	EC:3.4.23.45	Peptidases and inhibitors	ko01002	deepkoala