Detailed information of aflo_s0055.g81.t1 in Acropora florida

Genomic Location: sc0000055_pilon:1130069...1137534
NR annotation: XP_015772208.1, PREDICTED: pyruvate dehydrogenase E1 component subunit alpha, mitochondrial-like [Acropora digitifera]
Species Acropora florida · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
P08559Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial OS=Homo sapiens OX=9606 GN=PDHA1 PE=1 SV=3
P35486Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial OS=Mus musculus OX=10090 GN=Pdha1 PE=1 SV=1
A5A6L0Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial OS=Pan troglodytes OX=9598 GN=PDHA1 PE=2 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0004454 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF00676
all species →
E1_dhDehydrogenase E1 componentFamilyInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR017597
all species →
FamilyPyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup yInterproscan
IPR029061
all species →
Homologous_superfamilyThiamin diphosphate-binding foldInterproscan
IPR050642
all species →
FamilyPyruvate Dehydrogenase E1 Alpha SubunitInterproscan
IPR001017
all species →
DomainDehydrogenase, E1 componentInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR11516
all species →
PYRUVATE DEHYDROGENASE E1 COMPONENT, ALPHA SUBUNIT BACTERIAL AND ORGANELLARInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0004739
all species →
Molecular Functionpyruvate dehydrogenase (acetyl-transferring) activityInterproscan
GO:0006086
all species →
Biological Processacetyl-CoA biosynthetic process from pyruvateInterproscan
GO:0043231
all species →
Cellular Componentintracellular membrane-bounded organelleInterproscan
GO:0016624
all species →
Molecular Functionoxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptorInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K00161PDHA, pdhA; pyruvate dehydrogenase E1 component subunit alphaEC:1.2.4.1
Diabetic cardiomyopathyko05415deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Acropora florida tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Acropora florida, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.no expression matrix
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
TOP