Gene detail

Detailed information of aflo_s0514.g2.t1 in Acropora florida

Genomic Location: sc0000514_pilon:6118...17455
NR annotation: XP_029187073.2, trifunctional purine biosynthetic protein adenosine-3-like [Acropora millepora]
Species Acropora florida · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

aflo_s0514.g2.t1

ATGGAGGTGATTACCAGGGATATTCTTCAAAAAGCAGTCAATGGTTTGCGCAAAGAAGGCTGTAACTTTGTAGGTGTCCTGTTTGCTGGCATGATGTTGACGTCTCATGGACCCAGAGTTCTGGAGTTTAACTGTCGCTTTGGGGATCCGGAGACACAAGTAATCTTACCTCTTTTGAAGAGTGATCTCTATGCCACTATGATGGAATGTGTTAATGGTGACCTCAGCCTGTCTCTTCCCGTGTGGCACACTGATCGATATGCCGTGGGTGTGGTTGCTGCAAGTGGGGGCTATCCAGGTCCCATAAAGAAAGGATTTGTCATTCATGGATTGAAGGACTTGGAGAATGAAGACAATGTGGAGTTGCTTCATGCTGGAACAACCCTGAAGAAGATCAGTGATTCTGATACAGTGGTTACGTCTGGTGGAAGAGTGCTTACAGTGGTGGGTGTGGCTCAGAGAATAGAAGACGCTCAGAAAACAGCCTACAATAATATGAAAAAGATCTGCTTTGATGGTATACAGTACAGAAATGACATTGCTGCCAGGGCTTGTAGGTATGTCAGCAAGACAAAAGCTTTGACATATTCAGACGCTGGAGTGCATATTGATGCTGGCAATCTGTTGGTAAATGCCATCAAGCCATTAGCTGCATCTACATCTCGCCCGGGCTGTAAAGCTGATCTGGGTGGATTTGGAGGATTCTTTGATCTCAAGGCAGCTGGGTTCTCAGACCCTTTGCTTGTCAGTGGTACAGATGGAGTGGGCACTAAGCTGAAGGTTGCCCAAGCAGTGGGTAAGCATAGCTCAGTGGGGATCGATCTGGTTGCAATGTGTGTCAATGACATCCTTGCCCATGGTGCAGAACCCCTGTTCTTCTTAGACTACTTTGCCACTGGTAAACTTGATGTTGGCAAGGCAAAGGAGGTCATTAGTGGAATATCCCAAGGATGTTTAATGGCTGGATGTGCTTTACTGGGAGGTGAAACAGCTGAAATGCCAGGAATGTATTTACCAGGCGAATATGACATTGCTGGATTTGCAGTTGGTGCAGTTGAACGGGATCAAGTTCTCCCTCGCTCAGAGAGTATCAAACCAGACGATGTTGTGATTGGCTTGGCTTCATCTGGCGTTCACAGTAATGGCTTCAGTTTAGTTAGGCAGATCATTGATAGCTGTGGATTGGATTTCAATTCACCATGTCCGTTCCCAACAAATGAAGGCTTACAGTCAGTTACTAAAATTGGGGAAGCTTTACTTGAACCAACAAAGATTTACTGCAAGTCTGTGCTGCCTTTGATGAAAGATGGGAAGGTCAAGGCCTTTGCTCACATCACAGGTGGAGGCCTTCTAGAAAACATTCCCCGTGTCCTCCCACCTGGAGTTGGAGTGATGATAGATGCGACAACGTGGAACATGCCTATGGTGTTCGGTTGGATATTTGGCCAAGGAAATGTTGCCACTCAGGAGATGGCTAGAACATTTAACTGTGGCATAGGTGCTGTTCTCATTGTGGAGAAAGGAGTTGCTTCGTCAGTTTTAGATCACTTGAAAGGATTTGAACAGCAAGCTTGGATTATCGGCCAAGTTACAAAATGCATTGATGACAGCAGACCAGTGACTGTTAACCACCTTCAAGAAGTGCTCAGTGAATGTGCGAGGAAGTCCGACATCAAGGGTCAACAGGTTGACAAGGTCTTTGCCAATGGCCTGGCCAAAAGAGCCAAAATTTGCAGTGGCCAAACAGAACAGCAAGAAAACAGCCAAGAGATGAAAGTTGGTGTTCTCATATCTGGCTCGGGTACCAACTTGCAAGCATTGATTGATCGGAGTTTACAACAAGACAGTTGTGCAGACATTGTTTTGGTCATTTCCAATGTACCAGGTGTCCAAGGATTGAAGCGAGCTGAGGCGGCTGGAATATCAACCAAAGTAATTAAGCACAAGGATTTTAAGAGCCGGTTAGAGTTTGACATGGCAATGGATGCCGCCCTGAAAGAGGCTGGTGTTGAGTTGGTTTGCTTGGCAGGCTTCATGAGAATTGTGACGGGAGAGTTTGTACGCAAGTGGAATGGGCGGCTTCTTAACATCCATCCCTCCTTGTTGCCCTCTTTCAAAGGAATGAATGCACACAAAATGGTACTAGAGGCTGGTGTTTGCATAACAGGCTGCACGGTTCATTTTGTAGCGGAGGAGGTGGATGCGGGGGCAATAATAACTCAAGAGGCAGTTCCTGTGTTAAACAGTGATACAGAAGAAACACTGCAGGAACGAGTTAAATGTGCAGAACACAGGGCATACCCAAGAGCCATGGAGCTTCTGGCGAGTGGTAGGATCAAACTAAATCATGATAACAAAGTGCAGTGGATGTGGTGA

Transcript

aflo_s0514.g2.t1

CGTAAAGTTATATACATGGCAGACAAAGTTTTGATTATTGGCGGAGGTGGACGGGAAAATGCAATTGCCAGGAAAGTTGCTCAATCAAGCCATGTTGGTAAAATATTAATTGCGCCGGGAAATGCGGGAACAGTAAGCATTCCTTCAAAGACGAAGAACGTCTCCTCTTCTGAACTCGACCCTAACAACAACGAAAATGTTGTAAAATATTGTGTGGATAATAACGTGGATTTTGTCATCGTTGGTCCCGAGGTACCCCTAGCAAATGGCCTTTCAGATTCTCTTAGCGATAATAACATTCCGTGTTTTGGGCCAAGCAAATCTGCTGCACAGATCGAGTCTAGTAAACACTTTGCCAAAGATTTCATGCAACGACATAAAATTCCTACAGCACGTTGGAAGGCTTTTACAGATGTTGAAGAAGCGTGTAAACATATTGAAACGGCTGGCTATGAAGCGTTAATTGTGAAAGCAAGCGGACTGGCAGCTGGTAAAGGTGTTGTTGTTGCTGACAGTTTAAAACAGGCGAAACAAGCTGTTAGAGATATGCTGCAGGAAAAGAGATTGGGTGAGGCTGGATCAACAGTAGTAATAGAGGAAAAGCTAGAAGGCGAGGAAGTATCTGTGCTTTGTTTTACCGATGGAAGAACCATTGCTGTTATGCCTCCAGCCCAAGATCACAAGCGTTTGTTAGACCACGATCAGGGACCCAACACAGGAGGGATGGGTGCATATGCTCCCTGCCCACAGGTATCTGAGTTAACTATGGAGGTGATTACCAGGGATATTCTTCAAAAAGCAGTCAATGGTTTGCGCAAAGAAGGCTGTAACTTTGTAGGTGTCCTGTTTGCTGGCATGATGTTGACGTCTCATGGACCCAGAGTTCTGGAGTTTAACTGTCGCTTTGGGGATCCGGAGACACAAGTAATCTTACCTCTTTTGAAGAGTGATCTCTATGCCACTATGATGGAATGTGTTAATGGTGACCTCAGCCTGTCTCTTCCCGTGTGGCACACTGATCGATATGCCGTGGGTGTGGTTGCTGCAAGTGGGGGCTATCCAGGTCCCATAAAGAAAGGATTTGTCATTCATGGATTGAAGGACTTGGAGAATGAAGACAATGTGGAGTTGCTTCATGCTGGAACAACCCTGAAGAAGATCAGTGATTCTGATACAGTGGTTACGTCTGGTGGAAGAGTGCTTACAGTGGTGGGTGTGGCTCAGAGAATAGAAGACGCTCAGAAAACAGCCTACAATAATATGAAAAAGATCTGCTTTGATGGTATACAGTACAGAAATGACATTGCTGCCAGGGCTTGTAGGTATGTCAGCAAGACAAAAGCTTTGACATATTCAGACGCTGGAGTGCATATTGATGCTGGCAATCTGTTGGTAAATGCCATCAAGCCATTAGCTGCATCTACATCTCGCCCGGGCTGTAAAGCTGATCTGGGTGGATTTGGAGGATTCTTTGATCTCAAGGCAGCTGGGTTCTCAGACCCTTTGCTTGTCAGTGGTACAGATGGAGTGGGCACTAAGCTGAAGGTTGCCCAAGCAGTGGGTAAGCATAGCTCAGTGGGGATCGATCTGGTTGCAATGTGTGTCAATGACATCCTTGCCCATGGTGCAGAACCCCTGTTCTTCTTAGACTACTTTGCCACTGGTAAACTTGATGTTGGCAAGGCAAAGGAGGTCATTAGTGGAATATCCCAAGGATGTTTAATGGCTGGATGTGCTTTACTGGGAGGTGAAACAGCTGAAATGCCAGGAATGTATTTACCAGGCGAATATGACATTGCTGGATTTGCAGTTGGTGCAGTTGAACGGGATCAAGTTCTCCCTCGCTCAGAGAGTATCAAACCAGACGATGTTGTGATTGGCTTGGCTTCATCTGGCGTTCACAGTAATGGCTTCAGTTTAGTTAGGCAGATCATTGATAGCTGTGGATTGGATTTCAATTCACCATGTCCGTTCCCAACAAATGAAGGCTTACAGTCAGTTACTAAAATTGGGGAAGCTTTACTTGAACCAACAAAGATTTACTGCAAGTCTGTGCTGCCTTTGATGAAAGATGGGAAGGTCAAGGCCTTTGCTCACATCACAGGTGGAGGCCTTCTAGAAAACATTCCCCGTGTCCTCCCACCTGGAGTTGGAGTGATGATAGATGCGACAACGTGGAACATGCCTATGGTGTTCGGTTGGATATTTGGCCAAGGAAATGTTGCCACTCAGGAGATGGCTAGAACATTTAACTGTGGCATAGGTGCTGTTCTCATTGTGGAGAAAGGAGTTGCTTCGTCAGTTTTAGATCACTTGAAAGGATTTGAACAGCAAGCTTGGATTATCGGCCAAGTTACAAAATGCATTGATGACAGCAGACCAGTGACTGTTAACCACCTTCAAGAAGTGCTCAGTGAATGTGCGAGGAAGTCCGACATCAAGGGTCAACAGGTTGACAAGGTCTTTGCCAATGGCCTGGCCAAAAGAGCCAAAATTTGCAGTGGCCAAACAGAACAGCAAGAAAACAGCCAAGAGATGAAAGTTGGTGTTCTCATATCTGGCTCGGGTACCAACTTGCAAGCATTGATTGATCGGAGTTTACAACAAGACAGTTGTGCAGACATTGTTTTGGTCATTTCCAATGTACCAGGTGTCCAAGGATTGAAGCGAGCTGAGGCGGCTGGAATATCAACCAAAGTAATTAAGCACAAGGATTTTAAGAGCCGGTTAGAGTTTGACATGGCAATGGATGCCGCCCTGAAAGAGGCTGGTGTTGAGTTGGTTTGCTTGGCAGGCTTCATGAGAATTGTGACGGGAGAGTTTGTACGCAAGTGGAATGGGCGGCTTCTTAACATCCATCCCTCCTTGTTGCCCTCTTTCAAAGGAATGAATGCACACAAAATGGTACTAGAGGCTGGTGTTTGCATAACAGGCTGCACGGTTCATTTTGTAGCGGAGGAGGTGGATGCGGGGGCAATAATAACTCAAGAGGCAGTTCCTGTGTTAAACAGTGATACAGAAGAAACACTGCAGGAACGAGTTAAATGTGCAGAACACAGGGCATACCCAAGAGCCATGGAGCTTCTGGCGAGTGGTAGGATCAAACTAAATCATGATAACAAAGTGCAGTGGATGTGGTGATGACAGAGGGGCTCAGTGTTTGTGGCCCTGAAATGGACTGTGAGGCTAACACTCTCACTGACTTAGCTCCAGTTAACGAAATTCACTGTTTGAACTTAATCATGGTTTGTACAATCTTGAAAAGTCCTCGAAATTCAGGCATTTGTTTATGCCCTACCATATCTCTGATAAATGAAATAATTGTACTATTGAGAATTAATTCATGAACTTCTAAAAATTAAATACGAAAAGAGGTAGTGTAAACATCGGTAAACTGAGTATGAAAAAGTGGACAGAGTTTTGATCTTTTATTGAAACTTTGTCCTTGAAACTTGTTTGTCTGAGGTTGTGCAAACTATGTTTATGTATATCAGGTGTGGGCATTGGACTCGGAAAGCCATCTACTAACTGTTGCGTTACAAAAAAAAATTGTTGTTGTTTGCATATTCTTTAGAGATTTACAGGGATCAGAATTATTCTTCTTGTGAAACTACCGTATGTTCTAGGATATTAGAATAGGCCTGAGAGAAACGTGTGGAAACAAATTATTACCAGTACTCATCTGTATGTCAAGCAAAACCTAATATTGttaacaagtagattctcagttgctgtgggtctgttcagtaatgattatacgcatgatgtcaaaatgtggtaagaacaaaaaagtggcacataa

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
P21872	Trifunctional purine biosynthetic protein adenosine-3 OS=Gallus gallus OX=9031 GN=GART PE=1 SV=1
Q64737	Trifunctional purine biosynthetic protein adenosine-3 OS=Mus musculus OX=10090 GN=Gart PE=1 SV=3
Q59A32	Trifunctional purine biosynthetic protein adenosine-3 OS=Bos taurus OX=9913 GN=GART PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0002861 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF02769 all species →	AIRS_C	AIR synthase related protein, C-terminal domain	Domain	Interproscan
PF00586 all species →	AIRS	AIR synthase related protein, N-terminal domain	Domain	Interproscan
PF00551 all species →	Formyl_trans_N	Formyl transferase	Domain	Interproscan
PF01071 all species →	GARS_A	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain	Domain	Interproscan
PF02843 all species →	GARS_C	Phosphoribosylglycinamide synthetase, C domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR010918 all species →	Domain	PurM-like, C-terminal domain	Interproscan
IPR011054 all species →	Homologous_superfamily	Rudiment single hybrid motif	Interproscan
IPR036676 all species →	Homologous_superfamily	PurM-like, C-terminal domain superfamily	Interproscan
IPR004607 all species →	Family	Phosphoribosylglycinamide formyltransferase	Interproscan
IPR011761 all species →	Domain	ATP-grasp fold	Interproscan
IPR016188 all species →	Domain	PurM-like, N-terminal domain	Interproscan
IPR036921 all species →	Homologous_superfamily	PurM-like, N-terminal domain superfamily	Interproscan
IPR004733 all species →	Family	Phosphoribosylformylglycinamidine cyclo-ligase	Interproscan
IPR002376 all species →	Domain	Formyl transferase, N-terminal	Interproscan
IPR001555 all species →	Active_site	Phosphoribosylglycinamide formyltransferase, active site	Interproscan
IPR020559 all species →	Conserved_site	Phosphoribosylglycinamide synthetase, conserved site	Interproscan
IPR020560 all species →	Domain	Phosphoribosylglycinamide synthetase, C-domain	Interproscan
IPR020561 all species →	Domain	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain	Interproscan
IPR036477 all species →	Homologous_superfamily	Formyl transferase, N-terminal domain superfamily	Interproscan
IPR037123 all species →	Homologous_superfamily	Phosphoribosylglycinamide synthetase, C-domain superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR10520 all species →	TRIFUNCTIONAL PURINE BIOSYNTHETIC PROTEIN ADENOSINE-3-RELATED	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0004644 all species →	Molecular Function	phosphoribosylglycinamide formyltransferase activity	Interproscan
GO:0006189 all species →	Biological Process	'de novo' IMP biosynthetic process	Interproscan
GO:0005524 all species →	Molecular Function	ATP binding	Interproscan
GO:0046872 all species →	Molecular Function	metal ion binding	Interproscan
GO:0004641 all species →	Molecular Function	phosphoribosylformylglycinamidine cyclo-ligase activity	Interproscan
GO:0009058 all species →	Biological Process	biosynthetic process	Interproscan
GO:0004637 all species →	Molecular Function	phosphoribosylamine-glycine ligase activity	Interproscan
GO:0009113 all species →	Biological Process	purine nucleobase biosynthetic process	Interproscan
GO:0005829 all species →	Cellular Component	cytosol	Interproscan
GO:0006164 all species →	Biological Process	purine nucleotide biosynthetic process	Interproscan
GO:0046084 all species →	Biological Process	adenine biosynthetic process	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K11787	GART; phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase	EC:6.3.4.13 EC:2.1.2.2 EC:6.3.3.1	Antifolate resistance	ko01523	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Acropora florida tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Acropora florida, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →