Detailed information of agem_s0002.g470.t1 in Acropora gemmifera

Genomic Location: sc0000002_pilon:5432360...5450679
NR annotation: XP_029194280.2, calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type-like [Acropora millepora]
Species Acropora gemmifera · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
P22700Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type OS=Drosophila melanogaster OX=7227 GN=SERCA PE=1 SV=2
Q7PPA5Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type OS=Anopheles gambiae OX=7165 GN=SERCA PE=3 SV=5
Q292Q0Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type OS=Drosophila pseudoobscura pseudoobscura OX=46245 GN=SERCA PE=3 SV=2
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0001607 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF00702
all species →
Hydrolasehaloacid dehalogenase-like hydrolaseDomainInterproscan
PF00690
all species →
Cation_ATPase_NCation transporter/ATPase, N-terminusDomainInterproscan
PF00122
all species →
E1-E2_ATPaseE1-E2 ATPaseFamilyInterproscan
PF00689
all species →
Cation_ATPase_CCation transporting ATPase, C-terminusFamilyInterproscan
PF13246
all species →
Cation_ATPaseCation transport ATPase (P-type)FamilyInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR036412
all species →
Homologous_superfamilyHAD-like superfamilyInterproscan
IPR008250
all species →
Homologous_superfamilyP-type ATPase, A domain superfamilyInterproscan
IPR004014
all species →
DomainCation-transporting P-type ATPase, N-terminalInterproscan
IPR023299
all species →
Homologous_superfamilyP-type ATPase, cytoplasmic domain NInterproscan
IPR006068
all species →
DomainCation-transporting P-type ATPase, C-terminalInterproscan
IPR001757
all species →
FamilyP-type ATPaseInterproscan
IPR023298
all species →
Homologous_superfamilyP-type ATPase, transmembrane domain superfamilyInterproscan
IPR044492
all species →
DomainP-type ATPase, haloacid dehalogenase domainInterproscan
IPR018303
all species →
PTMP-type ATPase, phosphorylation siteInterproscan
IPR005782
all species →
FamilyP-type ATPase, subfamily IIA, SERCA-typeInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR42861
all species →
CALCIUM-TRANSPORTING ATPASEInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0000166
all species →
Molecular Functionnucleotide bindingInterproscan
GO:0005215
all species →
Molecular Functiontransporter activityInterproscan
GO:0005524
all species →
Molecular FunctionATP bindingInterproscan
GO:0016020
all species →
Cellular ComponentmembraneInterproscan
GO:0016887
all species →
Molecular FunctionATP hydrolysis activityInterproscan
GO:0005388
all species →
Molecular FunctionP-type calcium transporter activityInterproscan
GO:0006816
all species →
Biological Processcalcium ion transportInterproscan
GO:0006874
all species →
Biological Processintracellular calcium ion homeostasisInterproscan
GO:0015662
all species →
Molecular FunctionP-type ion transporter activityInterproscan
GO:0016021
all species →
Cellular ComponentmembraneInterproscan
GO:0034220
all species →
Biological Processmonoatomic ion transmembrane transportInterproscan
GO:0070588
all species →
Biological Processcalcium ion transmembrane transportInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K05853ATP2A; P-type Ca2+ transporter type 2AEC:7.2.2.10
Diabetic cardiomyopathyko05415deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of agem_s0002.g470.t1 across 48 RNA-seq samples of Acropora gemmifera. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

48Samples
3TPM > 0
1Conditions
61.3Max TPM
3.5Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
branch tip 48 3 3.54 61.31

Per sample · hover a bar for the full sample record

Show the sample table (48 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
SRR2169558 branch tip branch tip not recorded not recorded SRP062488 61.31
SRR3223317 branch tip branch tip not recorded not recorded SRP062488 55.43
SRR3223319 branch tip branch tip not recorded not recorded SRP062488 53.36
SRR3169421 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169422 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169423 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169425 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169426 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169518 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169527 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169528 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169529 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169530 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169531 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169532 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169533 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169534 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169535 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169536 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169537 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169538 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169539 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169540 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169541 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182410 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182448 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182557 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182684 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182685 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182686 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182775 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182776 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182777 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182778 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182779 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182780 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182781 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182784 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182785 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182786 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182787 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182788 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182789 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182790 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182791 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182792 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182793 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182794 branch tip branch tip not recorded not recorded SRP062488 0.00

Source: CnidoSite RNA-seq expression matrices (AGEMM_TPM, StringTie quantification over 48 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Acropora gemmifera tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated8agem_s0172.g12.t10.999999592358543
Negatively correlated3agem_s0028.g73.t1-0.61913276622605

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Acropora gemmifera, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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