Detailed information of agem_s0005.g24.t1 in Acropora gemmifera

Genomic Location: sc0000005_pilon:227196...233837
NR annotation: XP_015759266.1, PREDICTED: 26S protease regulatory subunit 10B [Acropora digitifera]
Species Acropora gemmifera · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
P6233326S proteasome regulatory subunit 10B OS=Homo sapiens OX=9606 GN=PSMC6 PE=1 SV=1
P6233526S proteasome regulatory subunit 10B OS=Ictidomys tridecemlineatus OX=43179 GN=PSMC6 PE=2 SV=1
P6233426S proteasome regulatory subunit 10B OS=Mus musculus OX=10090 GN=Psmc6 PE=1 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0000576 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF17862
all species →
AAA_lid_3AAA+ lid domainDomainInterproscan
PF16450
all species →
Prot_ATP_ID_OB_CProteasomal ATPase OB C-terminal domainDomainInterproscan
PF00004
all species →
AAAATPase family associated with various cellular activities (AAA)DomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR041569
all species →
DomainAAA ATPase, AAA+ lid domainInterproscan
IPR003960
all species →
Conserved_siteATPase, AAA-type, conserved siteInterproscan
IPR027417
all species →
Homologous_superfamilyP-loop containing nucleoside triphosphate hydrolaseInterproscan
IPR032501
all species →
DomainProteasomal ATPase, second OB domainInterproscan
IPR012340
all species →
Homologous_superfamilyNucleic acid-binding, OB-foldInterproscan
IPR050221
all species →
Family26S Proteasome Regulatory ATPaseInterproscan
IPR003959
all species →
DomainATPase, AAA-type, coreInterproscan
IPR003593
all species →
DomainAAA+ ATPase domainInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR23073
all species →
26S PROTEASOME REGULATORY SUBUNITInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0005524
all species →
Molecular FunctionATP bindingInterproscan
GO:0016887
all species →
Molecular FunctionATP hydrolysis activityInterproscan
GO:0008540
all species →
Cellular Componentproteasome regulatory particle, base subcomplexInterproscan
GO:0030433
all species →
Biological Processobsolete ubiquitin-dependent ERAD pathwayInterproscan
GO:0031597
all species →
Cellular Componentcytosolic proteasome complexInterproscan
GO:0036402
all species →
Molecular Functionproteasome-activating activityInterproscan
GO:0043161
all species →
Biological Processproteasome-mediated ubiquitin-dependent protein catabolic processInterproscan
GO:0045899
all species →
Biological Processpositive regulation of RNA polymerase II transcription preinitiation complex assemblyInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K03064PSMC6, RPT4; 26S proteasome regulatory subunit T4-Proteasomeko03051deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of agem_s0005.g24.t1 across 48 RNA-seq samples of Acropora gemmifera. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

48Samples
3TPM > 0
1Conditions
97.5Max TPM
4.5Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
branch tip 48 3 4.45 97.45

Per sample · hover a bar for the full sample record

Show the sample table (48 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
SRR3223319 branch tip branch tip not recorded not recorded SRP062488 97.45
SRR3223317 branch tip branch tip not recorded not recorded SRP062488 63.45
SRR2169558 branch tip branch tip not recorded not recorded SRP062488 52.80
SRR3169421 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169422 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169423 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169425 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169426 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169518 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169527 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169528 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169529 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169530 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169531 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169532 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169533 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169534 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169535 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169536 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169537 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169538 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169539 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169540 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169541 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182410 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182448 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182557 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182684 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182685 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182686 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182775 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182776 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182777 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182778 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182779 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182780 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182781 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182784 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182785 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182786 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182787 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182788 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182789 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182790 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182791 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182792 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182793 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182794 branch tip branch tip not recorded not recorded SRP062488 0.00

Source: CnidoSite RNA-seq expression matrices (AGEMM_TPM, StringTie quantification over 48 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Acropora gemmifera tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated10agem_s0047.g33.t10.999989692750854
Negatively correlated3agem_s0028.g73.t1-0.599044578944242

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Acropora gemmifera, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
TOP