Detailed information of agem_s0059.g130.t1 in Acropora gemmifera

Genomic Location: sc0000059_pilon:2204616...2217432
NR annotation: XP_044183808.1, 3-hydroxy-3-methylglutaryl-coenzyme A reductase-like [Acropora millepora]


 Gene Structure
More details in Jbrowse  Sequence
CDS
Transcript
Protein
 Uniprot
Uniprot termDescription
P163933-hydroxy-3-methylglutaryl-coenzyme A reductase OS=Strongylocentrotus purpuratus OX=7668 GN=HMGCR PE=2 SV=2
P040353-hydroxy-3-methylglutaryl-coenzyme A reductase OS=Homo sapiens OX=9606 GN=HMGCR PE=1 SV=1
Q5R6N33-hydroxy-3-methylglutaryl-coenzyme A reductase OS=Pongo abelii OX=9601 GN=HMGCR PE=2 SV=1

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF00368HMG-CoA_redHydroxymethylglutaryl-coenzyme A reductaseFamilyInterproscan
PF12349Sterol-sensingSterol-sensing domain of SREBP cleavage-activationFamilyInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR023076Conserved_siteHydroxymethylglutaryl-CoA reductase, class I/II, conserved siteInterproscan
IPR002202FamilyHydroxymethylglutaryl-CoA reductase, class I/IIInterproscan
IPR004554FamilyHydroxymethylglutaryl-CoA reductase, eukaryotic/archaeal typeInterproscan
IPR023282Homologous_superfamilyHydroxymethylglutaryl-CoA reductase, N-terminalInterproscan
IPR009029Homologous_superfamilyHydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain superfamilyInterproscan
IPR023074Homologous_superfamilyHydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain superfamilyInterproscan
IPR000731DomainSterol-sensing domainInterproscan
IPR009023Homologous_superfamilyHydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamilyInterproscan
IPR004816FamilyHydroxymethylglutaryl-CoA reductase, metazoanInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR105723-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASEInterproscan

 Gene Ontology
GO termsCategoryDescriptionSource
GO:0004420Molecular Functionhydroxymethylglutaryl-CoA reductase (NADPH) activityInterproscan
GO:0015936Biological Processcoenzyme A metabolic processInterproscan
GO:0005515Molecular Functionprotein bindingInterproscan
GO:0008299Biological Processisoprenoid biosynthetic processInterproscan
GO:0016616Molecular Functionoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptorInterproscan
GO:0005789Cellular Componentendoplasmic reticulum membraneInterproscan
GO:0050661Molecular FunctionNADP bindingInterproscan
GO:0005778Cellular Componentperoxisomal membraneInterproscan
GO:0016126Biological Processsterol biosynthetic processInterproscan

 KEGG pathway
KOEnzymeEnzyme IDpathwaymapIDSource
K00021HMGCR; hydroxymethylglutaryl-CoA reductase (NADPH)EC:1.1.1.34
Bile secretionko04976deepkoala

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