Gene detail

Detailed information of agem_s0159.g38.t1 in Acropora gemmifera

Genomic Location: sc0000159_pilon:762748...775176
NR annotation: XP_044182421.1, protein artemis-like isoform X2 [Acropora millepora]
Species Acropora gemmifera · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

agem_s0159.g38.t1

AGATTAATTTTGGTGTTCAGTCACAATAACTGTTTTGTTGCATTACCTTCAGGAGAGCTCCATCTGTGTTACATTGCTTCCTGCTGGCCATTGTGTTGGTTCTGTCATGTTCTTATTTGAAGGCCAACATGGAAATGTTCTTTACACAGGTGATTTCCGTTTGTCAGTAGGGGATGTTAAGAGGATACCATTTCTCCATGCAAATGGAAGTATAAAGGATATTAAAAGCATTTACATCGACACCACGTTTTGCCTGCCAAAGATGAACTCTCTTCCCACACGGGAACAAAGCAGAGATGCCATCATAGAACTAATAGAGAGGTGGTTTTCTCGTGGTCCCCAATACGTCGTCAGCTTGTTATGCAAAGGAATGTATGGCTTTGAGTATCTGCTTAAGGAAGTGGCGATGCACTTCAAAACCAAGGTCCATATTAGCCCTGAGCGACTGCGCATGTACCGGTATCTTCCAGACATGTTGCCTTATTTCACTACCGATGGTCGGGCTACAAAGATTCATGCCTGCAAATGGCAGGCTAATCGACATGATGCAGATTCCGATCTTCCTTGTGGGCAGTCAACCTTTCCCGCTCGTAAGATGAAAGTGCTACGAATCAAACCCGCAACGATGTGGGTTGCATTGAGCACAGAGGGAATGCCTGCTGACTTCAAGAGATATGACAAGGAACAAAGAGTGTGGCGAGTTGTGCATTCAATGCATGCATCAATGGAAGAGGTTCAAGATCTTGTTGGCTATCTCAAACCTTACCATGCTTATCCAAACGTACCTCCAGCCGGACTGGACACACTGGAAGATGCCTTTGAAAGGCTAAGGGGACTCACTCGACTTCATGAATGCAACTCTTGCAACAAAGACGAATCTGACGAATTGCATTTCAAGGAAATTACACCAGAGCACTGTGTCGAGATGCAAAAACCGCAGCCAAAGACACTCAAGCCATTATCTGGGATTCGACGGACAGTTACAGACGAGAAAGTCCTAGCGCAATGTAAAGAACTGGGTATCGAAGAGGAGCAATGCATAGCACCGGTTCCCAAGCGACGAAGAGGCAAGATTTTGGAAGAGAGAAAGGTCTATTCTTCGCGACAAGTTACAGAAGAGATGAGTTTAGACTTTGAAAAAGAATTAATAAGCACTTCCGTAAGTCAAACGCAAGACGTATCGTCTCTTGCAAGCCGTCACGCACCTCTTTTACTCGAAGATAGCGGAGACGTGGATAAATGGACAGAAGGAGTTGGAGGGGAAGTTCAGAAGGAAGAGAAACCTTCAAAAAAAAATTTTCAAACGGAATGGAAACATGAGGACATTGGCACAGAACGTAATCAAGGTGGGAAAACCGAGTCTTGCAAAGGTTTCTTGGTTGAAGGTGGCGGGGTCAATGCGTTTGAAAATTCAGTTCACTCTAAAACAAAACGTGATGAGGTTAAATTCCCTGAACTTGAGCAACCAAAGTTCCTGTCCCCAGGGACACCTACAAAATCACAATCGCAGGGAGGGGGGGCCGGGTCTAATTTTGATGTCCCTCCCTCCCCTGGGAATGCGAAGCCACGCGCAGAGAGACTGAAATTCCTCCATCAGAGGATTCAAAACGGAGACACGATTAGCATGACAAAGGCTAACGATAAGGGAGCTCGTTAATCAATGGTCCATGCATCTCTGTTTCAATTCAACCAGGCTTGCAGAATCCCAGTAGACTTCGGGTAGGCTCCACTTTTGAAGAGAGAGAGCCTATCGGATGAACTACACGCAATACGAGGGGTGCGTGGAAAATTTTCCGCGCTCGTCTCGCGCGGGTAGATGTATTTCGCTCGCTCCTTTGTCTTCACATGACGTCACGGCacttgagcgacattttgctcttgttttgtacaccaacatggccgtctcattacgtgagtgaaaaccaagaataCGCTACTACTTGCAGTCGAAAATGACGGCTATTTGACAGTCATACGAGGAAAAAAACCCGTCGTTCGTACCTGCTGTTATACTTGTTTTCTTCATCAGCTCGCCTTTTTCGAACCTCTCTTGATTTTCTTGACCAAAATATGGCCTTCTACTCAAGATTGTTACCTTTCTTCGCGTACATTCCAAAGTGGTCTCGCAACTTTTACGGAAAGATTGTGTGACGACTCGAAAGGAATTCTGCTAAAGATCCATATCTAGAAAaggccatttccaggtacacttcagccctattgcaagccgactcgaggtgcgcagtctttgtttcgaatatcagttttcattcatgttgaaattagaactaattaccataacaacaatttcgcaccaggactcgctttaaaatagcgactgaggggaactgggaaatggtctatCAATGTCCAGTCTTGCAACCACAGGCCTTTAAACACGTCTGCTCTTGCCAAATTACGTGAAATGGCTTTCTCATTTACACCAACGGTGACTCAAATTACTTCGGTTCAAGGTATTATATGTTAACCTATCAACAACTGTATTTGGACCGGTTATATCGTAGGCTCGATTACCAGCCGCTGTTCGGGAAAGGAGCCCGCGTCTCTTCTCGGGGAGGGTAGACCAGACACGAGAGAGCGGCGGAAATCGAGCCTTGTAAAATCGACGACTATAAAATTTCGAATTACGTACATTCATCAATAATATATTTATATCTATTTCATTCACGGGCTGTAAAAAATATGAACAATCTAAAAATATTACTTCTACAAATTCACTTCTATTTGTTAATTATTGCCTATTGACCTAGCCTTTCCGTGAAAAAGAGGCTACAATCGGCCTCATCTTCGTGTAAACCCACTCCATCCTTCATTTCGCTTCTGTCGGGGCTAAAATGGCGGTTGTTGGAGATTTGGTTAAGAGTCAATCTCAGTTTTGTTTCTGATCCTTACCAGGCCTAAGTGGTTCAAAGCTTGGATAGAACTATTCACCCTTTGAACAACTGGGGCCAGGTCGCTAAGCGCGTACAATCTAATAGGGACGGGGTTGATATCGGCATGCTCCAACTGAACACGCCTTAACCGTACGAGGATTTAAAGCGCTACCTAGAAGATAACTCAATAGACCTatccagcggccatctcaaattctatgcttctgaaaaaaaagatattatgggatgctcagggggtaaattcatgttTCATGTGGGTATTACGTTGGTTTTAGGTTTTGAAATTTCCAAACCAGTATGACTTTTTCATCTCCCTTGTTTCAGACGGCAATTTATCTGTGTCAAAGGAAATATAAAAACCTGGATTGGAGAAACAAAACCAGATTTTCTTGCACATGTACGTATTTGCCCCCTAAAATATCAAAATAAAACTTATTCTTAAAGAGATTTACATAACAGCCAATTAAAAAATATTTAGCCCGTTTGCTGACGGGGTCAATGAACTGCATCACGAAGACATTGTTTCGAGCGTACAAAATGATGTAAAAAAAAAGTTTTTCATTCGCTAAATTCACCTAACAATGCTCTTACTTGTACGCTTATAAAAAAAACGGCCAACTAATTTATAGCACAAAAAACTATAATTGCTAAAAGGGATTATCTTTTAAGGCCTCGTTTCCGTGGGCGTGAACATGTTTCGGTCGTGCGAAAACTGGGGCGAGAGGAATAAACCTCTCTCTTACTCTCATGCCATTTTTCGCGGCGCGACCGAAACACGTTCAGGCTCACAGAAAGGCTTGCTCCTTAGGCTAATTAATTTCTTGCAATTTTTTAAGCCGTCATAAATTATCACCTACTGATCGTGCTGTTTTAGAATTCAAGGTTGAATTTTCCTGAAAACAATACGATAAGAGCTTTTACCTTTGAAAGACAGCAAATTTCTGAATAAATTCCACTCTTTCGTATCTTTCTCAATATAAACACTTAaaacactttagaataaaaataagcgactaaaaatttggaatgacgtttcgctgaatcgttcattttcaacttcataaaaagaacattttgaaatgagtttttttatgtagaaaaagcgtgtaaaaatcacgttttatatgcttaaaaactaaaaAAAATTGTAGAAAACAAAAGttttgcgttaactgagtgttgagtataggtttctcttgctgaatgaaacgcatttcacagattaagcattaaaattttgcacCGCCTGAAGATCTTTGTTCTTATGATTTCGGAcaccgaaacctttttcaacgcattgatgagcactccgatattggaaaacacctgcgtgtcgctcgcaatcagaggaacaaaggtctTCCGCAGGAAAAGTTAACCATATAGGAACTaatttcaaaatgatgaacgattcatcgaagaaattttatcactcatttttattcttaagtgtctttcaaaacccttcgttattaAGCACTCAAGACCCTGTCTCCAAATTGCAAAAACTAGTGGATAGAGGGACGACCATGAGGTTAGAAAACATTTGGTTGGACAAAAGGAAATCTACCCTTATTAAAATATAAATGGTCGACAAAAGAATGAACTCTACGCATGCGCAATAATCTATTTTTCTAACGACGAgcgggtagcattcaaatgattttttcctcaatgctaacgagtgcgatcgggtctcaaggtggtcgcaacaagatggctgccgctaaatttctttggcttcactttcgaaacaatagaaggtcgatccagtctttttttagatcagtgGGAATCTAGGTAGTTCCGGTCCCTTATAAGCCCAAAAGACCAGAATGAAAGGACTGTAACTACCCAAGATTCATCACAAACTTCAATTCTATTGAACGTAGTCACTGATCTAAAAAAAAAAGACTGGATCGAGGAAACTATTaggtcatttagatcgccgccatcttgttgaggccactttacgcaccacagctttggatctacggcctgaaggttatgaatctaaacca

Protein

UniProt (Swiss-Prot top hit)

No Swiss-Prot hit above the reporting threshold for this gene.

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0004342 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF07522 all species →	DRMBL	DNA repair metallo-beta-lactamase	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR011084 all species →	Domain	DNA repair metallo-beta-lactamase	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR23240 all species →	DNA CROSS-LINK REPAIR PROTEIN PSO2/SNM1-RELATED	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0000723 all species →	Biological Process	telomere maintenance	Interproscan
GO:0003684 all species →	Molecular Function	damaged DNA binding	Interproscan
GO:0006303 all species →	Biological Process	double-strand break repair via nonhomologous end joining	Interproscan
GO:0035312 all species →	Molecular Function	5'-3' DNA exonuclease activity	Interproscan
GO:0036297 all species →	Biological Process	interstrand cross-link repair	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

No KEGG orthology assignment for agem_s0159.g38.t1.

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of agem_s0159.g38.t1 across 48 RNA-seq samples of Acropora gemmifera. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

48Samples

38TPM > 0

1Conditions

940.8Max TPM

293.4Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM	Mean, relative to max
branch tip	48	38	293.38	940.84

Per sample · hover a bar for the full sample record

Show the sample table (48 samples)

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR3169421	branch tip	branch tip	not recorded	not recorded	SRP062488	940.84
SRR3182778	branch tip	branch tip	not recorded	not recorded	SRP062488	908.99
SRR3182784	branch tip	branch tip	not recorded	not recorded	SRP062488	795.70
SRR3182789	branch tip	branch tip	not recorded	not recorded	SRP062488	677.37
SRR3169529	branch tip	branch tip	not recorded	not recorded	SRP062488	609.66
SRR3182781	branch tip	branch tip	not recorded	not recorded	SRP062488	588.64
SRR3169539	branch tip	branch tip	not recorded	not recorded	SRP062488	562.80
SRR3182794	branch tip	branch tip	not recorded	not recorded	SRP062488	540.54
SRR3182785	branch tip	branch tip	not recorded	not recorded	SRP062488	486.67
SRR3169541	branch tip	branch tip	not recorded	not recorded	SRP062488	481.25
SRR3182410	branch tip	branch tip	not recorded	not recorded	SRP062488	458.28
SRR3169538	branch tip	branch tip	not recorded	not recorded	SRP062488	444.19
SRR3182775	branch tip	branch tip	not recorded	not recorded	SRP062488	436.74
SRR3169535	branch tip	branch tip	not recorded	not recorded	SRP062488	382.53
SRR3169531	branch tip	branch tip	not recorded	not recorded	SRP062488	372.69
SRR3169422	branch tip	branch tip	not recorded	not recorded	SRP062488	368.36
SRR3169527	branch tip	branch tip	not recorded	not recorded	SRP062488	362.89
SRR3182779	branch tip	branch tip	not recorded	not recorded	SRP062488	331.24
SRR3169425	branch tip	branch tip	not recorded	not recorded	SRP062488	328.04
SRR3182557	branch tip	branch tip	not recorded	not recorded	SRP062488	318.63
SRR3169530	branch tip	branch tip	not recorded	not recorded	SRP062488	308.64
SRR3182792	branch tip	branch tip	not recorded	not recorded	SRP062488	282.26
SRR3182793	branch tip	branch tip	not recorded	not recorded	SRP062488	280.96
SRR3169533	branch tip	branch tip	not recorded	not recorded	SRP062488	276.94
SRR3169534	branch tip	branch tip	not recorded	not recorded	SRP062488	274.53
SRR3169426	branch tip	branch tip	not recorded	not recorded	SRP062488	268.84
SRR3169537	branch tip	branch tip	not recorded	not recorded	SRP062488	260.75
SRR3169423	branch tip	branch tip	not recorded	not recorded	SRP062488	259.00
SRR3182684	branch tip	branch tip	not recorded	not recorded	SRP062488	241.47
SRR3169532	branch tip	branch tip	not recorded	not recorded	SRP062488	227.88
SRR3182686	branch tip	branch tip	not recorded	not recorded	SRP062488	217.88
SRR3182448	branch tip	branch tip	not recorded	not recorded	SRP062488	215.20
SRR3169528	branch tip	branch tip	not recorded	not recorded	SRP062488	202.15
SRR3169518	branch tip	branch tip	not recorded	not recorded	SRP062488	154.92
SRR3182788	branch tip	branch tip	not recorded	not recorded	SRP062488	94.62
SRR3182791	branch tip	branch tip	not recorded	not recorded	SRP062488	79.47
SRR3223317	branch tip	branch tip	not recorded	not recorded	SRP062488	24.29
SRR3223319	branch tip	branch tip	not recorded	not recorded	SRP062488	16.27
SRR2169558	branch tip	branch tip	not recorded	not recorded	SRP062488	0.00
SRR3169536	branch tip	branch tip	not recorded	not recorded	SRP062488	0.00
SRR3169540	branch tip	branch tip	not recorded	not recorded	SRP062488	0.00
SRR3182685	branch tip	branch tip	not recorded	not recorded	SRP062488	0.00
SRR3182776	branch tip	branch tip	not recorded	not recorded	SRP062488	0.00
SRR3182777	branch tip	branch tip	not recorded	not recorded	SRP062488	0.00
SRR3182780	branch tip	branch tip	not recorded	not recorded	SRP062488	0.00
SRR3182786	branch tip	branch tip	not recorded	not recorded	SRP062488	0.00
SRR3182787	branch tip	branch tip	not recorded	not recorded	SRP062488	0.00
SRR3182790	branch tip	branch tip	not recorded	not recorded	SRP062488	0.00

Source: CnidoSite RNA-seq expression matrices (AGEMM_TPM, StringTie quantification over 48 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Acropora gemmifera tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

Direction	Partners	Most correlated partner	PCC
Positively correlated	0	not in this network	-
Negatively correlated	46	agem_s0247.g29.t1	-0.426181076796901

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Acropora gemmifera, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	ready	open →
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →