Detailed information of agem_s0238.g8.t1 in Acropora gemmifera

Genomic Location: sc0000238_pilon:227426...249483
NR annotation: XP_029207817.2, sodium/potassium-transporting ATPase subunit alpha-3-like [Acropora millepora]
Species Acropora gemmifera · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
P18907Sodium/potassium-transporting ATPase subunit alpha-1 OS=Equus caballus OX=9796 GN=ATP1A1 PE=3 SV=1
P05023Sodium/potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1
Q5RDR3Sodium/potassium-transporting ATPase subunit alpha-1 OS=Pongo abelii OX=9601 GN=ATP1A1 PE=2 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0001595 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF00689
all species →
Cation_ATPase_CCation transporting ATPase, C-terminusFamilyInterproscan
PF00122
all species →
E1-E2_ATPaseE1-E2 ATPaseFamilyInterproscan
PF00690
all species →
Cation_ATPase_NCation transporter/ATPase, N-terminusDomainInterproscan
PF13246
all species →
Cation_ATPaseCation transport ATPase (P-type)FamilyInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR050510
all species →
FamilyCation transport ATPase (P-type)Interproscan
IPR036412
all species →
Homologous_superfamilyHAD-like superfamilyInterproscan
IPR023298
all species →
Homologous_superfamilyP-type ATPase, transmembrane domain superfamilyInterproscan
IPR018303
all species →
PTMP-type ATPase, phosphorylation siteInterproscan
IPR006068
all species →
DomainCation-transporting P-type ATPase, C-terminalInterproscan
IPR005775
all species →
FamilyP-type ATPase subfamily IIC, subunit alphaInterproscan
IPR023214
all species →
Homologous_superfamilyHAD superfamilyInterproscan
IPR008250
all species →
Homologous_superfamilyP-type ATPase, A domain superfamilyInterproscan
IPR044492
all species →
DomainP-type ATPase, haloacid dehalogenase domainInterproscan
IPR023299
all species →
Homologous_superfamilyP-type ATPase, cytoplasmic domain NInterproscan
IPR004014
all species →
DomainCation-transporting P-type ATPase, N-terminalInterproscan
IPR001757
all species →
FamilyP-type ATPaseInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR43294
all species →
SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHAInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0005391
all species →
Molecular FunctionP-type sodium:potassium-exchanging transporter activityInterproscan
GO:0005886
all species →
Cellular Componentplasma membraneInterproscan
GO:0006883
all species →
Biological Processintracellular sodium ion homeostasisInterproscan
GO:0019829
all species →
Molecular FunctionATPase-coupled monoatomic cation transmembrane transporter activityInterproscan
GO:0030007
all species →
Biological Processintracellular potassium ion homeostasisInterproscan
GO:0036376
all species →
Biological Processsodium ion export across plasma membraneInterproscan
GO:1902600
all species →
Biological Processproton transmembrane transportInterproscan
GO:1990573
all species →
Biological Processpotassium ion import across plasma membraneInterproscan
GO:0005524
all species →
Molecular FunctionATP bindingInterproscan
GO:0006813
all species →
Biological Processpotassium ion transportInterproscan
GO:0008556
all species →
Molecular FunctionP-type potassium transmembrane transporter activityInterproscan
GO:0016020
all species →
Cellular ComponentmembraneInterproscan
GO:0000166
all species →
Molecular Functionnucleotide bindingInterproscan
GO:0005215
all species →
Molecular Functiontransporter activityInterproscan
GO:0016887
all species →
Molecular FunctionATP hydrolysis activityInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K01539ATP1A; sodium/potassium-transporting ATPase subunit alphaEC:7.2.2.13
Exosomeko04147deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of agem_s0238.g8.t1 across 48 RNA-seq samples of Acropora gemmifera. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

48Samples
2TPM > 0
1Conditions
120.5Max TPM
2.6Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
branch tip 48 2 2.59 120.51

Per sample · hover a bar for the full sample record

Show the sample table (48 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
SRR3223319 branch tip branch tip not recorded not recorded SRP062488 120.51
SRR3223317 branch tip branch tip not recorded not recorded SRP062488 3.78
SRR2169558 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169421 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169422 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169423 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169425 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169426 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169518 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169527 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169528 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169529 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169530 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169531 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169532 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169533 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169534 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169535 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169536 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169537 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169538 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169539 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169540 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3169541 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182410 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182448 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182557 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182684 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182685 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182686 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182775 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182776 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182777 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182778 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182779 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182780 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182781 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182784 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182785 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182786 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182787 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182788 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182789 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182790 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182791 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182792 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182793 branch tip branch tip not recorded not recorded SRP062488 0.00
SRR3182794 branch tip branch tip not recorded not recorded SRP062488 0.00

Source: CnidoSite RNA-seq expression matrices (AGEMM_TPM, StringTie quantification over 48 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Acropora gemmifera tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated9agem_s0341.g15.t10.999999992666574
Negatively correlated3agem_s0028.g73.t1-0.364117160204309

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Acropora gemmifera, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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