Gene detail

Detailed information of aint_s0015.g53.t1 in Acropora intermedia

Genomic Location: sc0000015_pilon:899247...915955
NR annotation: XP_015765211.1, PREDICTED: 3-hydroxy-3-methylglutaryl-coenzyme A reductase-like [Acropora digitifera]
Species abbreviation AINTE · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

aint_s0015.g53.t1

ATGTCACGAAGTGGAATTTCGAGCCTTTTCTATACCCATGGCAAACTTTGCTCTTATCATCCGGTTGAGGTATTATTGGTTTGTATAACAGGAACTGTTTGTCTGCTAACTTTGAACCTCTACGATGCGACGCATCACTTTGCAAGCCAGCAAAACGAAGCTTCCGGTGAAAAAATTTCTTTCCCTGTGGCCTTGCATGTAGGTCCTACAAGTTATTTCTTTGCATTGGTGTGCATTTATCTTCAATGCAAAAAGCTTATTCAGCAGGGATCTTCATATGTTTTTGGGTTTGTGTCTGTGTTTGCAATCTTTTCGTGCATAGTTTTCAGTTCTGTCATTGCCAACTTATATGGAAGAGATGTCTGGATTATAAGAGAGGCCTTGCCATATTTCTTCCTTTTGAGTGATTTCAATACTGCCAGTTCACTTGTGAGGCACACTCTTCAGTCTTCTTCGTATGATGGAGTGCATGTCAGGATTGCCGAGGCCATTGCTTATCAGGGACCCATCATCACTCTTAACACACTTGTTGGAGCTCTGGTTATTGGTGTAGGAACTCTTTCAGGAGTTGAAGAGTTAGAAACCATTTGTCAATTTGGCTGTTTGTCGCTAGTCACATATTATGTGATCTTCATGACTTTTTTGCCAGCCTGTCTGTCACTGTTTCTGGAGCTGTGCACAGGAAGAGGACAGTGCAACCCAAGATGGCAGATACCTTCCAAAGGTCTTCCAGCTGAAGATCTAGATCCAAATCCTGTGGTTCAGGGTGTCAAACTTATAATGTCTACAGGCTTGATGTTCGTTCATGTGCATCGTTGGTTTTTGTTGAGAAGTGAGAACTATGAAGGTTCTCATGGAATGTCAAGTTATGTGGACGATAGATGGTTCACGAGGTTTTTAGCTGAAAATACTGAACAGATCATTTTTGCAGTATTTGCTGCTGGTCTTGCCACAAGATACATTTTGTCGTACAAAGATGAAAGAACAGATGACCAAGTTGAGAAGAAACCGGCAGCAATAACAGAGGATGAACAAGTGTACCCTACTCGGGACACAAGGGGCCAAGTTGGCTGTAATGTTCAAATTCATACCCCAGATGGAAAGGAACAATGTACAGATTGTAACAAGCCAAGTGGGAAGAGTTTTGCTTGTGGAACATCTGCTAGTAACAGAATTAAGGTTAATTTTTTATCAAGAAAAATGAGTGAAATATGTGGGAATTTGCCCTCTGTTAGCCAAAGATCTGGGCTGTTGGAAAGGAGGCGAACTGTGAGTGAAGGTGATGGCTTTAGTGAATTTTGTTTCAGTGAAGACAGTGTTCTCATGTCAGAATGTGTAAAAAACAACAGCAGCACACCAACACTAGAAAACAGAGAACGTAGCCTGGAGGAATGCAAGGCAGTCTTGAAACAATCGGATGGAGTATTCAGCTTGAGTGACAAGGAGATCCAGATGCTAGTTGAAGCAAAAACCATTCCTGCACATCAGCTTGAAAAGTTTTTAAAAGATCCATGCAGGGCTGTTAAGATCAGGCGTGAGGTTGTGTCCAAGAAGCTTTCAGGTGAAACAGGTTTATCGGATCTTCCCAGTGAGCACTTTGACTACTCAAGGGTTGTTGGATCTTGTTGCGAAAATGTAGTTGGGTACATGCCTCTCCCAGTTGGCGTTGCTGGTCCTCTCTTACTGGATGGTGAAAACTACCATGTTCCTATGGCAACTACTGAAGGCTGTTTAGTGGCAAGCACAAACAGAGGCTGCAGAGCCTTATTGTTAAGTGGAGGAGTAAGGAGCTCCGTGTTTGGTGATGCTATGACGAGAGGTCCAGTTGTTAGATTTCCTTCAGCACTTCTTGCAAGTGATGTTAAACTTTGGTTAGAAAAAGAGCAAAACTTTATGGAAATCAAACAAGTGTTCAACAGTACAAGCAGATTTGCCAGATTAAAGTCAGTCAAGTGTGTGGTTGCTGGTCGCTTGCTGTTTGTTAGATTTGTAGCTACAACTGGTGATGCCATGGGCATGAATATGGTGTCAAAGGGAACAGAGAAAGCTCTTCATTGTTTGCATGGACACTTCCCGACAATGGAAATCATAAGTTTAAGTGGAAACTTTTGTTCTGATAAGAAGGCAACTGGACTAAACTGGATTGAAGGCCGAGGGAAGTCTGTGGTCTGTGAAGCAATTGTACCTGGTCATATTGTTAATAAGATATTAAAGACGTCAGTGGTAGCACTAACGGAACTCAATGTCAGTAAGAACCTTGTTGGCTCAGCCATGGCAGGAGCCCTTGGAGGATTTAACGCTCACGCAGCTAACGTTGTAACGGCAATTTTTATAGCTACAGGACAGGATCCTGCTCAATGTGTTACAAGCAGCCATTGTATAACTCTACTTGAACCATGTGGACCTAAAAACGAAGATTTATATATCAGCTGCACAATGCCGTCGGTAGAGGTCGGTACAGTTGGAGGTGGCACCATTTTAGGTCCACAGTCAGCCTGCCTAAAGATGCTTGGTGTCCATGGCGCTCATGAGTCCGAGCCTGGTAGAAACGCAATTAAATTGGCTCAAATAGTTTGCGGCACAGTCCTTGCTGGAGAACTGTCCTTACTATCTGCTCTAGCTGCCGGTCATCTTGTGAAAAGCCATTTAGCTCTTAACAGGTCCACTGCTAACATTTCAATGGAAGATGCAAGCAAAAACTGTGCTGTTTTATGA

Transcript

aint_s0015.g53.t1

GTAAATTGAACTCTTGTGCTGCACTTTGTCATTCCTTCTTCGGACAAATCTCTGTAGGTAAAATGAATGCAATGGATTGTTTGGTTGCGTCATCATAACTCTGTAACCTGGCCGCCCGTCTTCCAACATTATAGTTTGTCGTCGCGGTTTGGATGTCGTTTTGCATTTTGCCATGTCACGAAGTGGAATTTCGAGCCTTTTCTATACCCATGGCAAACTTTGCTCTTATCATCCGGTTGAGGTATTATTGGTTTGTATAACAGGAACTGTTTGTCTGCTAACTTTGAACCTCTACGATGCGACGCATCACTTTGCAAGCCAGCAAAACGAAGCTTCCGGTGAAAAAATTTCTTTCCCTGTGGCCTTGCATGTAGGTCCTACAAGTTATTTCTTTGCATTGGTGTGCATTTATCTTCAATGCAAAAAGCTTATTCAGCAGGGATCTTCATATGTTTTTGGGTTTGTGTCTGTGTTTGCAATCTTTTCGTGCATAGTTTTCAGTTCTGTCATTGCCAACTTATATGGAAGAGATGTCTGGATTATAAGAGAGGCCTTGCCATATTTCTTCCTTTTGAGTGATTTCAATACTGCCAGTTCACTTGTGAGGCACACTCTTCAGTCTTCTTCGTATGATGGAGTGCATGTCAGGATTGCCGAGGCCATTGCTTATCAGGGACCCATCATCACTCTTAACACACTTGTTGGAGCTCTGGTTATTGGTGTAGGAACTCTTTCAGGAGTTGAAGAGTTAGAAACCATTTGTCAATTTGGCTGTTTGTCGCTAGTCACATATTATGTGATCTTCATGACTTTTTTGCCAGCCTGTCTGTCACTGTTTCTGGAGCTGTGCACAGGAAGAGGACAGTGCAACCCAAGATGGCAGATACCTTCCAAAGGTCTTCCAGCTGAAGATCTAGATCCAAATCCTGTGGTTCAGGGTGTCAAACTTATAATGTCTACAGGCTTGATGTTCGTTCATGTGCATCGTTGGTTTTTGTTGAGAAGTGAGAACTATGAAGGTTCTCATGGAATGTCAAGTTATGTGGACGATAGATGGTTCACGAGGTTTTTAGCTGAAAATACTGAACAGATCATTTTTGCAGTATTTGCTGCTGGTCTTGCCACAAGATACATTTTGTCGTACAAAGATGAAAGAACAGATGACCAAGTTGAGAAGAAACCGGCAGCAATAACAGAGGATGAACAAGTGTACCCTACTCGGGACACAAGGGGCCAAGTTGGCTGTAATGTTCAAATTCATACCCCAGATGGAAAGGAACAATGTACAGATTGTAACAAGCCAAGTGGGAAGAGTTTTGCTTGTGGAACATCTGCTAGTAACAGAATTAAGGTTAATTTTTTATCAAGAAAAATGAGTGAAATATGTGGGAATTTGCCCTCTGTTAGCCAAAGATCTGGGCTGTTGGAAAGGAGGCGAACTGTGAGTGAAGGTGATGGCTTTAGTGAATTTTGTTTCAGTGAAGACAGTGTTCTCATGTCAGAATGTGTAAAAAACAACAGCAGCACACCAACACTAGAAAACAGAGAACGTAGCCTGGAGGAATGCAAGGCAGTCTTGAAACAATCGGATGGAGTATTCAGCTTGAGTGACAAGGAGATCCAGATGCTAGTTGAAGCAAAAACCATTCCTGCACATCAGCTTGAAAAGTTTTTAAAAGATCCATGCAGGGCTGTTAAGATCAGGCGTGAGGTTGTGTCCAAGAAGCTTTCAGGTGAAACAGGTTTATCGGATCTTCCCAGTGAGCACTTTGACTACTCAAGGGTTGTTGGATCTTGTTGCGAAAATGTAGTTGGGTACATGCCTCTCCCAGTTGGCGTTGCTGGTCCTCTCTTACTGGATGGTGAAAACTACCATGTTCCTATGGCAACTACTGAAGGCTGTTTAGTGGCAAGCACAAACAGAGGCTGCAGAGCCTTATTGTTAAGTGGAGGAGTAAGGAGCTCCGTGTTTGGTGATGCTATGACGAGAGGTCCAGTTGTTAGATTTCCTTCAGCACTTCTTGCAAGTGATGTTAAACTTTGGTTAGAAAAAGAGCAAAACTTTATGGAAATCAAACAAGTGTTCAACAGTACAAGCAGATTTGCCAGATTAAAGTCAGTCAAGTGTGTGGTTGCTGGTCGCTTGCTGTTTGTTAGATTTGTAGCTACAACTGGTGATGCCATGGGCATGAATATGGTGTCAAAGGGAACAGAGAAAGCTCTTCATTGTTTGCATGGACACTTCCCGACAATGGAAATCATAAGTTTAAGTGGAAACTTTTGTTCTGATAAGAAGGCAACTGGACTAAACTGGATTGAAGGCCGAGGGAAGTCTGTGGTCTGTGAAGCAATTGTACCTGGTCATATTGTTAATAAGATATTAAAGACGTCAGTGGTAGCACTAACGGAACTCAATGTCAGTAAGAACCTTGTTGGCTCAGCCATGGCAGGAGCCCTTGGAGGATTTAACGCTCACGCAGCTAACGTTGTAACGGCAATTTTTATAGCTACAGGACAGGATCCTGCTCAATGTGTTACAAGCAGCCATTGTATAACTCTACTTGAACCATGTGGACCTAAAAACGAAGATTTATATATCAGCTGCACAATGCCGTCGGTAGAGGTCGGTACAGTTGGAGGTGGCACCATTTTAGGTCCACAGTCAGCCTGCCTAAAGATGCTTGGTGTCCATGGCGCTCATGAGTCCGAGCCTGGTAGAAACGCAATTAAATTGGCTCAAATAGTTTGCGGCACAGTCCTTGCTGGAGAACTGTCCTTACTATCTGCTCTAGCTGCCGGTCATCTTGTGAAAAGCCATTTAGCTCTTAACAGGTCCACTGCTAACATTTCAATGGAAGATGCAAGCAAAAACTGTGCTGTTTTATGAGACTAAGTGAAATCTTGACAAAGCTAACTATTGCTTTCATGAGAGGCCAGCCCACAAGTGACTGTTGGAAGATACAACAAATTGCCAGGCGCCCCAGCCACCCTCTTTCGGGTTTATAAAATCAAAGCTGAGGGACGTGGCCTTGTGGAGTGGACAAAACAATTCATTTGATGGTCTTATTTTTACTGGATTGATGCGGAATATAGAAAAGCTTTTCGTCTATTTTATTGCAAGAAATAAGAACAAATAACATCTTATTTATTTTAACAAGTTTATGAAAACAAAACTTATTTCAAGAAAGTATTTTAATATGA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
P16393	3-hydroxy-3-methylglutaryl-coenzyme A reductase OS=Strongylocentrotus purpuratus OX=7668 GN=HMGCR PE=2 SV=2
A7Z064	3-hydroxy-3-methylglutaryl-coenzyme A reductase OS=Bos taurus OX=9913 GN=HMGCR PE=2 SV=2
P04035	3-hydroxy-3-methylglutaryl-coenzyme A reductase OS=Homo sapiens OX=9606 GN=HMGCR PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0005293 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00368 all species →	HMG-CoA_red	Hydroxymethylglutaryl-coenzyme A reductase	Family	Interproscan
PF12349 all species →	Sterol-sensing	Sterol-sensing domain of SREBP cleavage-activation	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR023074 all species →	Homologous_superfamily	Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain superfamily	Interproscan
IPR009023 all species →	Homologous_superfamily	Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily	Interproscan
IPR023076 all species →	Conserved_site	Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site	Interproscan
IPR002202 all species →	Family	Hydroxymethylglutaryl-CoA reductase, class I/II	Interproscan
IPR004816 all species →	Family	Hydroxymethylglutaryl-CoA reductase, metazoan	Interproscan
IPR004554 all species →	Family	Hydroxymethylglutaryl-CoA reductase, eukaryotic/archaeal type	Interproscan
IPR009029 all species →	Homologous_superfamily	Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain superfamily	Interproscan
IPR000731 all species →	Domain	Sterol-sensing domain	Interproscan
IPR023282 all species →	Homologous_superfamily	Hydroxymethylglutaryl-CoA reductase, N-terminal	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR10572 all species →	3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0004420 all species →	Molecular Function	hydroxymethylglutaryl-CoA reductase (NADPH) activity	Interproscan
GO:0015936 all species →	Biological Process	coenzyme A metabolic process	Interproscan
GO:0005789 all species →	Cellular Component	endoplasmic reticulum membrane	Interproscan
GO:0008299 all species →	Biological Process	isoprenoid biosynthetic process	Interproscan
GO:0050661 all species →	Molecular Function	NADP binding	Interproscan
GO:0005515 all species →	Molecular Function	protein binding	Interproscan
GO:0016616 all species →	Molecular Function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	Interproscan
GO:0005778 all species →	Cellular Component	peroxisomal membrane	Interproscan
GO:0016126 all species →	Biological Process	sterol biosynthetic process	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K00021	HMGCR; hydroxymethylglutaryl-CoA reductase (NADPH)	EC:1.1.1.34	Bile secretion	ko04976	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.