Gene detail

Detailed information of alor_g17631.t1 in Acropora loripes

Genomic Location: Acropora_loripes_138:549073...562723
NR annotation: XP_044177166.1, phosphoribosylformylglycinamidine synthase-like [Acropora millepora]
Species Acropora loripes · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

alor_g17631.t1

ATGGAGGATTGCAGCGTTCTTAGGTTTTACAGTTTCCCTGGATTATCGTCTGGAAAGCAGGGTGTTACGCTTGCGAAACTGAAAACCGTGTCCTCTCGTTTCACAGTGATCGATTTATTGACTGAAATGTGCTTTAATGTCAGTGTCCAAGGACATGACCTTACCAATGAAGAGCTAAGTAACCTAATATGGCTTTTGAGCGATTCTTTCGAGGAAGGACGCGTTCGTCAAACTTCTTTCCTGGATGAGTCTTCAGAAGCAAATGATGGTTGCAAAGTCCTGATAGAAATCGGGCCAAGGTTGAACTTTTCAACAGCGTGGTCGACAAACGCTGTTTCGATTTGTCGCTCCATAGGGTTGACGAAAATTGACAGAATCGAGAGATCTTTTCGCTATTTGCTGCGAGTGAGCTCCAATGGCGATTCCCGAAAAATTACGAAGGAGGAAGAAAATGCTTTTGCGGCGAAATTGCACGACAGAATGACCGAATGTCGCTATGAAAAGCCGCTGGGTAGTTTCAAAATAAACATTCAAACTGAACAATGTTATGAAGTGGATGTGTTAGGTGAAGGTCGCACAGCACTCGAGAAAGTAAATCGAGATCTTGGTTTGGCATTTGACAATTGGGATCTGGAGTATTATACTAAACTATTCCAAGAGAGAGTGAAGAGAAACCCGACCAGCGTTGAATGCTTTGATTTGGCACAGTCAAATAGCGAACATTCACGCCATTGGTTCTTCAAAGGAAAATTGACAGTTGATGGACAAGAAGTGAAGGAGTCGCTAATGAAGATGGTGATGAGGACTCAGGAGACAAGCAATGATAATAATGTTATTAAGTTCAGCGACAACAGCAGTGCTATAACTGGTTACGAAGTTTCTGTACTACTGCCTGAACACTGCAGTGAAGCTGCCAGATATCGGCTTAAGCAAAAAGCTGCGCGACATATCATTTTCACTGCAGAGACGCACAATTTTCCAACAGGTGTGGCACCATTTCCTGGTGCAACAACAGGAACAGGGGGGCGCATAAGAGATGTGCAGGCTGCTGGCAGAGGAGGTCATGTTGTTGCTGGCACTGCAGGTTACTGCTTTGGAAATCTGCACATACCAGGTTATGACCTTCCCTGGGAAGAAACAACATTTGTTTATCCAAACAACATGGCCCCTCCGGTGGAGATTGCTGTGGAAGCTAGCAATGGTGCTTCAGATTATGGGAACAAGTTTGGAGAGCCTGTTCTTGCTGGATTTGCTAGATCCTTTGGAATGATACTGCCAAGTGGAGAGCGTCGTGAATGGGTGAAGCCGATAATGTTTAGTGGTGGAATTGGAACGATAGATAGTGATGGAGTGACAAAACTTGCACCAGAAAAAGGGATGTCGGTTGTCAAGGTTGGTGGACCTGTGTATCGCCTTGGTGTTGGTGGTGGTGCTGCGTCATCTATCCAAGTACAAGGGGATAATGAGTCAGAACTGGACTTTGGTGCGGTTCAACGGGGTGATGCAGAAATGGAGCAGAAGCTGAATCGCGCAATCAGAGCCTGCATTGAAATGGGTCGCAAGAATCCAATATGTAGCATTCACGACCAAGGAGCTGGAGGCAATGGAAATGTGTTGAAAGAGATCTGTGAGCCTGCTGGAGCCATCATTCATGTCAAAGATTTCATCCTTGGCGACCCAACTCTTTCTGTGCTTGAGTTGTGGGGGGCAGAGTATCAGGAAAGTAATGCTTTACTGGTGCACAAGGAAAACAGGCATGTACTGCAGAGCATCTGTGACAGAGAGAAGGTACCAGTGTCCTTTGTTGGGCAGATTACAGGTGATGGAAGAATTGTGTTGGAAGATGACACTTTATCCTCAACCAATGGTCAACTGCAGGAGAACAATGGAGTGCCAAATAAGCGGCAGAGAACAACAACTTGTCCTGTTGATTTGGAACTGGAGGTTGTGTTGGGCAAAATGCCACAAAAGATCTTCAATTTTGAGCGGGTACAGGCAAAGCTGAAGCCATTACAAATAGGATCTGATCTCACAATAAAAGAAATGTTAGACAGAGTGCTACGCCTGCCAGCTGTGGGCAGCAAGAGATATCTCACAAACAAGGTGGACCGTAGTGTGACAGGTCTTGTTGCACAGCAGCAGTGTGTTGGACCATTACACACACCTGTAGCAGACGTAGCAGTTACTGCATTGACACACTTTGACATTGTGGGTTCAGCAACTGCTATTGGTGAACAGCCAATCAAAGGTTTAGTTAGTCCAGCATGTGGGGCCCATATGGCTGTAGGAGAAGCTCTGACAAATTTGGTGTTTGCAAGAATTACTGATTTGAAGGATGTAAAGTGCAGTGCTAATTGGATGTGGCCAGCAAAGTTACCAGGGGAAGGTGCTGCTCTGTACGATGCCTGTGAAGCCATGTGCGATGTCATGTCACATCTTGGTATTGCAGTTGATGGAGGGAAAGATTCCCTGAGCATGGCAGCAAGGGTTGGCAATAAAACCGTCAAGGCTCCTGGTTCACTGGTCATTTCTGTGTATGCAGCTTGCCCTGATGTTCGAGCCACAGTCACACCAGATCTGAAGCTCCCAGATGGAAGAGGGAATCTCCTGTGGGTGAAATTTGGCAGTGATTCCAAATTCAGACTGGGGGGGAGTGCTTTGGCTCAGGTGTTTAATCAGCTGGGAGATGAAGCTCCAGATTTAGATCATGTAGAGACCTTTGACGCAGCCTTCAGAATCACTCAGGAGCTGATAGTGCAAGGCCTTATTGTGTCCGGTCACGACATCAGTGATGGTGGTCTCATTACTACAATCTTGGAAATGGCTTTTGCTGGAAACTGTGGTCTTAATGTTGATGTTCCTTGCTCAGAGAACTTCAGTCCAACAGTGAGCAAGGCAGTTGATGTTCTCTTTGCAGAAGAGCTTGGAATTGTCCTGGAAGTTAAAGATAGCAACATTGAGAGGGTCATCAATACCTTTCGTGAGAAGCAAGTTCCTTGTTACCTAATTGGCAAAGCAATTGGGCTGGGTGAGGATTCTTTTGTGTCAATCCATGTTGGAGGTGAGCTTTTGTTGGAGCAGAGAATGGTTGATTTGCGGGATGTGTGGGAAGCAACCAGTTTCCAGCTGGAGAGGCTGCAGTCAAACCCACAGTGTGTAAAGGAAGAGGAAGCTGGTCTTTGTAAACGATTTGCACCAATGTACAAGCTGTCATTTGAGCCAATGTCTTCAGTCTTGCCAAGTGAGAAGGGTGTTATCCATCCAAAAGTGGCCATCATACGAGAAGAGGGCAGCAATGGAGACAGGGAGATGGTGGCAAGCTTTCACATGGCAGGTTTCGAAGCATGGGATGTGACCATGAATGATTTGTGCAAAGGAACGGTGTCCCTTGAGGAGTTCCGTGGAGCAGTGTTTGTGGGTGGCTTTAGTTATGCTGACGTACTTGGTTCTGCGAAAGGGTGGGCTGCAGTATGTCAAATAAACAGCACTGTGCGCAGTCAATTGGATGCCTTCTTCACCAGATCTGACACTTTCAGCTTAGGAGTGTGCAATGGCTGCCAGCTCATGGGGCTGCTTGGTTGGATTGGCCAGGCTGTGGACACTTCAGACGATGGAAGTTTGAGGCAAGGAGTTTGCTTTACTCACAACACCTCTGAAAGATATGAATCCAGGTTTGTGACGGTGGCAATCCAGTCCAGTCCTGCCATGATGCTGCGTGGCATGGAAGGATCTACACTGGGAATATGGGTAGCACACGGCGAGGGACGAATTCAGTTCCGTAGCGACTCTGTCCTTCAGAACATCAAAGCCAACAAACTCATTCCGCTGTGCTATGTCAATGATGAAGGCATTCCAACAACTCTATATCCTCTGAATCCAAACGGATCCCCAGAGGGGATTGCTGGTCTTTGCTCTACAGATGGCCGGCATCTTGCCATGATGCCCCACCCAGAAAGATGTACATTACTTTGGCAATGGCCTTGGATGCCATTGGATTGGAGGAATTCGCTCGAGGCATCACCATGGTTGCAGATGTTTCACAATGCGTACAAATGGTGTGTGGAGACTTCATAA

Transcript

alor_g17631.t1

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
O15067	Phosphoribosylformylglycinamidine synthase OS=Homo sapiens OX=9606 GN=PFAS PE=1 SV=4
Q5SUR0	Phosphoribosylformylglycinamidine synthase OS=Mus musculus OX=10090 GN=Pfas PE=1 SV=1
Q9M8D3	Probable phosphoribosylformylglycinamidine synthase, chloroplastic/mitochondrial OS=Arabidopsis thaliana OX=3702 GN=At1g74260 PE=2 SV=3

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0004624 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF13507 all species →	GATase_5	CobB/CobQ-like glutamine amidotransferase domain	Domain	Interproscan
PF18072 all species →	FGAR-AT_linker	Formylglycinamide ribonucleotide amidotransferase linker domain	Domain	Interproscan
PF18076 all species →	FGAR-AT_N	Formylglycinamide ribonucleotide amidotransferase N-terminal	Domain	Interproscan
PF02769 all species →	AIRS_C	AIR synthase related protein, C-terminal domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR036921 all species →	Homologous_superfamily	PurM-like, N-terminal domain superfamily	Interproscan
IPR036604 all species →	Homologous_superfamily	Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily	Interproscan
IPR029062 all species →	Homologous_superfamily	Class I glutamine amidotransferase-like	Interproscan
IPR041609 all species →	Domain	Phosphoribosylformylglycinamidine synthase, linker domain	Interproscan
IPR010073 all species →	Family	Phosphoribosylformylglycinamidine synthase PurL	Interproscan
IPR040707 all species →	Domain	Phosphoribosylformylglycinamidine synthase, N-terminal	Interproscan
IPR036676 all species →	Homologous_superfamily	PurM-like, C-terminal domain superfamily	Interproscan
IPR010918 all species →	Domain	PurM-like, C-terminal domain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR10099 all species →	PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0004642 all species →	Molecular Function	phosphoribosylformylglycinamidine synthase activity	Interproscan
GO:0006189 all species →	Biological Process	'de novo' IMP biosynthetic process	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K01952	PFAS, purL; phosphoribosylformylglycinamidine synthase	EC:6.3.5.3	Purine metabolism	ko00230	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Acropora loripes tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Acropora loripes, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →