Genomic Location: Acropora_loripes_24:2818084...2851743
NR annotation: XP_029198688.2, inhibitor of nuclear factor kappa-B kinase subunit beta-like isoform X2 [Acropora millepora]
| CDS | ||||
| alor_g20514.t1 | ||||
| Transcript |
| alor_g20514.t1 |
| Protein |
| alor_g20514.t1 |
| Uniprot term | Description | |||
|---|---|---|---|---|
| O15111 | Inhibitor of nuclear factor kappa-B kinase subunit alpha OS=Homo sapiens OX=9606 GN=CHUK PE=1 SV=2 | |||
| O88351 | Inhibitor of nuclear factor kappa-B kinase subunit beta OS=Mus musculus OX=10090 GN=Ikbkb PE=1 SV=1 | |||
| Q28DZ1 | Inhibitor of nuclear factor kappa-B kinase subunit alpha OS=Xenopus tropicalis OX=8364 GN=chuk PE=2 SV=1 |
| Gene family | Subfamily |
|---|---|
| Ubiquitin Family | UBD|Other|Jab_MPN |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF08969 | USP8_dimer | USP8 dimerisation domain | Domain | Interproscan |
| PF00069 | Pkinase | Protein kinase domain | Domain | Interproscan |
| PF00001 | 7tm_1 | 7 transmembrane receptor (rhodopsin family) | Family | Interproscan |
| PF18397 | IKBKB_SDD | IQBAL scaffold dimerization domain | Domain | Interproscan |
| PF01398 | JAB | JAB1/Mov34/MPN/PAD-1 ubiquitin protease | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR046375 | Homologous_superfamily | IKBKB, scaffold dimerization domain superfamily | Interproscan |
| IPR000555 | Domain | JAB1/MPN/MOV34 metalloenzyme domain | Interproscan |
| IPR000719 | Domain | Protein kinase domain | Interproscan |
| IPR015063 | Domain | USP8 dimerisation domain | Interproscan |
| IPR044098 | Domain | STAMBP/STALP-like, MPN domain | Interproscan |
| IPR017441 | Binding_site | Protein kinase, ATP binding site | Interproscan |
| IPR000276 | Family | G protein-coupled receptor, rhodopsin-like | Interproscan |
| IPR041185 | Domain | IKBKB, scaffold dimerization domain | Interproscan |
| IPR051180 | Family | Inhibitor of nuclear factor kappa-B kinase | Interproscan |
| IPR037518 | Domain | MPN domain | Interproscan |
| IPR029071 | Homologous_superfamily | Ubiquitin-like domain superfamily | Interproscan |
| IPR000626 | Domain | Ubiquitin-like domain | Interproscan |
| IPR008271 | Active_site | Serine/threonine-protein kinase, active site | Interproscan |
| IPR011009 | Homologous_superfamily | Protein kinase-like domain superfamily | Interproscan |
| IPR017452 | Domain | GPCR, rhodopsin-like, 7TM | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR22969 | IKB KINASE | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0008233 | Molecular Function | peptidase activity | Interproscan |
| GO:0008237 | Molecular Function | metallopeptidase activity | Interproscan |
| GO:0004672 | Molecular Function | protein kinase activity | Interproscan |
| GO:0005524 | Molecular Function | ATP binding | Interproscan |
| GO:0006468 | Biological Process | protein phosphorylation | Interproscan |
| GO:0016579 | Biological Process | protein deubiquitination | Interproscan |
| GO:0061578 | Molecular Function | K63-linked deubiquitinase activity | Interproscan |
| GO:0070536 | Biological Process | protein K63-linked deubiquitination | Interproscan |
| GO:0140492 | Molecular Function | metal-dependent deubiquitinase activity | Interproscan |
| GO:0004930 | Molecular Function | G protein-coupled receptor activity | Interproscan |
| GO:0007186 | Biological Process | G protein-coupled receptor signaling pathway | Interproscan |
| GO:0016020 | Cellular Component | membrane | Interproscan |
| GO:0004674 | Molecular Function | protein serine/threonine kinase activity | Interproscan |
| GO:0005737 | Cellular Component | cytoplasm | Interproscan |
| GO:0008384 | Molecular Function | IkappaB kinase activity | Interproscan |
| GO:0008385 | Cellular Component | IkappaB kinase complex | Interproscan |
| GO:0018105 | Biological Process | peptidyl-serine phosphorylation | Interproscan |
| GO:0033209 | Biological Process | tumor necrosis factor-mediated signaling pathway | Interproscan |
| GO:0045944 | Biological Process | positive regulation of transcription by RNA polymerase II | Interproscan |
| GO:0051092 | Biological Process | positive regulation of NF-kappaB transcription factor activity | Interproscan |