Genomic Location: chr_8:24836213...24854537
NR annotation: XP_031574558.1, thioredoxin reductase 2, mitochondrial-like isoform X2 [Actinia tenebrosa]
Species Alvinactis idsseensis sp. Nov. · all data for this species · gene families
| CDS |
| alvinactis_v1_g17547 |
| Transcript |
| alvinactis_v1_g17547 |
| Protein |
| alvinactis_v1_g17547 |
| UniProt accession | Description |
|---|---|
| Q9JLT4 | Thioredoxin reductase 2, mitochondrial OS=Mus musculus OX=10090 GN=Txnrd2 PE=1 SV=4 |
| Q9Z0J5 | Thioredoxin reductase 2, mitochondrial OS=Rattus norvegicus OX=10116 GN=Txnrd2 PE=1 SV=3 |
| Q9NNW7 | Thioredoxin reductase 2, mitochondrial OS=Homo sapiens OX=9606 GN=TXNRD2 PE=1 SV=3 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0001632 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF02852 all species → | Pyr_redox_dim | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain | Domain | Interproscan |
| PF07992 all species → | Pyr_redox_2 | Pyridine nucleotide-disulphide oxidoreductase | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR016156 all species → | Homologous_superfamily | FAD/NAD-linked reductase, dimerisation domain superfamily | Interproscan |
| IPR012999 all species → | Active_site | Pyridine nucleotide-disulphide oxidoreductase, class I, active site | Interproscan |
| IPR004099 all species → | Domain | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain | Interproscan |
| IPR006338 all species → | Family | Thioredoxin/glutathione reductase selenoprotein | Interproscan |
| IPR036188 all species → | Homologous_superfamily | FAD/NAD(P)-binding domain superfamily | Interproscan |
| IPR046952 all species → | Family | Glutathione reductase/thioredoxin reductase-like | Interproscan |
| IPR023753 all species → | Domain | FAD/NAD(P)-binding domain | Interproscan |
| IPR001100 all species → | Family | Pyridine nucleotide-disulphide oxidoreductase, class I | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR42737 all species → | GLUTATHIONE REDUCTASE | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0016491 all species → | Molecular Function | oxidoreductase activity | Interproscan |
| GO:0050660 all species → | Molecular Function | flavin adenine dinucleotide binding | Interproscan |
| GO:0016668 all species → | Molecular Function | oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor | Interproscan |
| GO:0004791 all species → | Molecular Function | thioredoxin-disulfide reductase (NADPH) activity | Interproscan |
| GO:0004362 all species → | Molecular Function | glutathione-disulfide reductase (NADPH) activity | Interproscan |
| GO:0005739 all species → | Cellular Component | mitochondrion | Interproscan |
| GO:0005829 all species → | Cellular Component | cytosol | Interproscan |
| GO:0006749 all species → | Biological Process | glutathione metabolic process | Interproscan |
| GO:0034599 all species → | Biological Process | cellular response to oxidative stress | Interproscan |
| GO:0045454 all species → | Biological Process | cell redox homeostasis | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K22182 | TXNRD; thioredoxin reductase (NADPH) | EC:1.8.1.9 | Hepatocellular carcinoma | ko05225 | deepkoala |
Genes whose expression across the transcriptome samples of Alvinactis idsseensis sp. Nov. tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Alvinactis idsseensis sp. Nov., and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
