Detailed information of alvinactis_v1_g21070 in Alvinactis idsseensis sp. Nov.

Genomic Location: chr_11:2576320...2580697
NR annotation: XP_020896413.1, delta(24)-sterol reductase isoform X1 [Exaiptasia diaphana]
Species Alvinactis idsseensis sp. Nov. · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
Q15392Delta(24)-sterol reductase OS=Homo sapiens OX=9606 GN=DHCR24 PE=1 SV=2
Q60HC5Delta(24)-sterol reductase OS=Macaca fascicularis OX=9541 GN=DHCR24 PE=2 SV=2
Q8VCH6Delta(24)-sterol reductase OS=Mus musculus OX=10090 GN=Dhcr24 PE=1 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0012273 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF01565
all species →
FAD_binding_4FAD binding domain DomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR016169
all species →
Homologous_superfamilyFAD-binding, type PCMH, subdomain 2Interproscan
IPR006094
all species →
DomainFAD linked oxidase, N-terminalInterproscan
IPR036318
all species →
Homologous_superfamilyFAD-binding, type PCMH-like superfamilyInterproscan
IPR016166
all species →
DomainFAD-binding domain, PCMH-typeInterproscan
IPR040165
all species →
FamilyDelta(24)-sterol reductaseInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR10801
all species →
24-DEHYDROCHOLESTEROL REDUCTASEInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0050660
all species →
Molecular Functionflavin adenine dinucleotide bindingInterproscan
GO:0071949
all species →
Molecular FunctionFAD bindingInterproscan
GO:0000246
all species →
Molecular Functiondelta24(24-1) sterol reductase activityInterproscan
GO:0005737
all species →
Cellular ComponentcytoplasmInterproscan
GO:0008202
all species →
Biological Processsteroid metabolic processInterproscan
GO:0016020
all species →
Cellular ComponentmembraneInterproscan
GO:0016628
all species →
Molecular Functionoxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptorInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K09828DHCR24, DWF1; Delta24-sterol reductaseEC:1.3.1.72
EC:1.3.1.-
Steroid biosynthesisko00100deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Alvinactis idsseensis sp. Nov. tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Alvinactis idsseensis sp. Nov., and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.no expression matrix
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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