Genomic Location: chr_16:7805493...7823992
NR annotation: XP_028512792.1, phenylalanine-4-hydroxylase [Exaiptasia diaphana]
Species Alvinactis idsseensis sp. Nov. · all data for this species · gene families
| CDS |
| alvinactis_v1_g29708 |
| Transcript |
| alvinactis_v1_g29708 |
| Protein |
| alvinactis_v1_g29708 |
| UniProt accession | Description |
|---|---|
| Q2KIH7 | Phenylalanine-4-hydroxylase OS=Bos taurus OX=9913 GN=PAH PE=2 SV=1 |
| P16331 | Phenylalanine-4-hydroxylase OS=Mus musculus OX=10090 GN=Pah PE=1 SV=4 |
| P00439 | Phenylalanine-4-hydroxylase OS=Homo sapiens OX=9606 GN=PAH PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0002367 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF01842 all species → | ACT | ACT domain | Domain | Interproscan |
| PF00351 all species → | Biopterin_H | Biopterin-dependent aromatic amino acid hydroxylase | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR005961 all species → | Family | Phenylalanine-4-hydroxylase, tetrameric form | Interproscan |
| IPR002912 all species → | Domain | ACT domain | Interproscan |
| IPR036329 all species → | Homologous_superfamily | Aromatic amino acid monoxygenase, C-terminal domain superfamily | Interproscan |
| IPR041912 all species → | Domain | Eukaryotic phenylalanine-4-hydroxylase, catalytic domain | Interproscan |
| IPR045865 all species → | Homologous_superfamily | ACT-like domain | Interproscan |
| IPR018301 all species → | Binding_site | Aromatic amino acid hydroxylase, iron/copper binding site | Interproscan |
| IPR019774 all species → | Domain | Aromatic amino acid hydroxylase, C-terminal | Interproscan |
| IPR019773 all species → | Family | Tyrosine 3-monooxygenase-like | Interproscan |
| IPR036951 all species → | Homologous_superfamily | Aromatic amino acid hydroxylase superfamily | Interproscan |
| IPR001273 all species → | Family | Aromatic amino acid hydroxylase | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR11473 all species → | AROMATIC AMINO ACID HYDROXYLASE | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0004505 all species → | Molecular Function | phenylalanine 4-monooxygenase activity | Interproscan |
| GO:0006559 all species → | Biological Process | L-phenylalanine catabolic process | Interproscan |
| GO:0004497 all species → | Molecular Function | monooxygenase activity | Interproscan |
| GO:0005506 all species → | Molecular Function | iron ion binding | Interproscan |
| GO:0009072 all species → | Biological Process | aromatic amino acid metabolic process | Interproscan |
| GO:0016714 all species → | Molecular Function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K00500 | phhA, PAH; phenylalanine-4-hydroxylase | EC:1.14.16.1 | Folate biosynthesis | ko00790 | deepkoala |
Genes whose expression across the transcriptome samples of Alvinactis idsseensis sp. Nov. tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Alvinactis idsseensis sp. Nov., and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
