Gene detail

Detailed information of amic_s0001.g101.t2 in Acropora microphthalma

Genomic Location: sc0000001_pilon:1372318...1384472
NR annotation: XP_029197886.1, paired amphipathic helix protein Sin3a-like isoform X1 [Acropora millepora]
Species Acropora microphthalma · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

amic_s0001.g101.t2

ATGAAGAGGGTCCGTCCTGAAGACCATGACAGTGTCTATGGGCAGAACAGACAGGGTTTCCGCCCTCCCCCGGTTCTTGCACCAAACCCTGTTGGTATGGCAACTAATTATGATCAGCCCCTGCAGGATGGATTGAGTGGGTTGTCACAGTTTCCTGCTGCCGCACAAATGGCAGGGGCTCCAGGGTTTCAAGTGCAATCGCAAAATCCACAGTCCCATCCTCATGTACAGAATGCATCTTCAACACATCACCAAggtcaaactcaggttcatgcacaagcacaggctcagggacagCAACAACAGTTTCAAAGACTGAAGGTTGAGGATGCTCTGTCATACTTGGACCAAGTCAAGCTCCAGTTTGGCAACCAGCCTCAAGTTTACAATGATTTCTTGGATATCATGAAAGAGTTTAAGTCACAAAGTATTGACACTCCTGGAGTTATCAGCAGAGTTTCATCACTGTTCAAAGGTCACCCAGAACTCATTGTAGGCTTCAACACCTTCCTCCCTCCTGGGTACAAGATTGAGGTTCATGCTAGTGACCCAGGAACAGTCTCAGTTACAGCTCCTAATGGACAATCACAGATTACAACCATCCTTCAGCCAAATCAAAATCAACATCCACTTCATCAGTCTAGTGGCcaacagggacagcaacagcaacaagctcagcaaaaacaacagcagcagcaacagcaacaacaacagcagcctctgcagtcaccaacagcccagcaaGGACAGGGTCAACAGCCTGTGGAGTTTAACCATGCCATTAATTATGTCAACAAGATAAAGAATCGATTCCAAGGACAACCTGACATTTATAAGGCTTTCTTGGAAATCCTTCATACATATCAAAAGGAGCAGAAAATCATTAAGGAGGCTGCTATGCAAGGAACTCCACTTTCTGAGCAAGAGATTTACTTGAGAGAAGCTAAACTTGCTAATGAGGTTTACAAACAAGTTGCCAGGCTGTTTGAAAATCAAGAAGATTTGTTGCAAGAGTTCAGTCAGTTCCTTCCTGATGCAAATGGTGCTGCAACAATGCCTGGGGGTTTATTGTCCTCAAGTAAACTGCAGTCTCACCTAACTTCAGCAAGAAATGAATATGCACCTCCTGCGAAAAAACCTGCAGTGGGTCTGAATTCATCAAAACGCATCACACACCAGATAAGAAGAAATTCCAACAGTGTTTCATCATCACCTACACATTCCCAAACGAAGAAGAAATCAAGAAGTGCAATCAAAGATGTCTCCTTCGCAGAAGCACAACAAATTGGAACCTTGTCAGAATTTTCGTTCTTTGAAAAGGTGAAAAAAGCTCTAAAAAATAATGAGCTTTATAATAATTTTCTTCGCTGTCTTGTACTCTTCAATCAAGAAGTGATATCCAGATCAGAACTTGTGCAATTGGCTGCAAACTTCCTTGGTAAATACGCAGAGCTGTTCCAATGGTTCAAGGAATTCCTTGGTTATAAGGATTCATCTCCAATGGAAAGTGTGGCAAGTTTCAAAGAAAGAACGTCAGGAGAACTTCACCACCTTGAAATTGATTATTCTTCTTGTAAGAGGTATGGCACAAGTTACAGAGCCCTTCCCAAAAGCTACACACAGCCCAAGTGCAGTGGCCGTACAGCCCTGTGTAGAGAAGTCCTCAATGACACCTGGGTGTCCTTCCCATCTTGGTCAGAAGACACACCCTTTCCAGGAACAAGGAAAACACAATATGAAGAGTACATATTCAGGTGTGAGGATGAAAGGTTTGAGTTGGATGTTGTGTTGGAATCAAATCTCTCCACTATTCGGGTATTAGAAGCCATCCAGAAAAAGCTTCAGAGAATGCCAGCTGAAGAACAAGCTAAATTTCGACTCGACAGCTGTATAGGAGGAACCTCAGAATTCATCCACAGGAAAGCTATTCAGAGGATTTATGGAGACAAGGCTCCTGATATAGTTGACGGTTTGAAAAAAACACCTGCAGTTGCTGTCCCACTTGTATTAAAAAGATTAAAGACCAAAGAAGAGGAATGGCGTGAGTCTCAAAGACAATTTAACAAAATATGGAGAGATCAAAATGAAAAATATTATCTGAAGTCTTTGGATCATCAAGGCATTACATTTAAACAAAACGACTTGAAATCCATGAGGTCAAAAAGCCTTATTAATGAAATAGAGACAATTTATGATGAGAGACAAGAGCAAGCTGCAGAAGGTAATGGGGATGCAGCTGGTCCCCACTTAACCTTCAGCTATCAGGACAAGTCCATTCTAGATGACGCTGCTGGGCTCATTGTTCATCACATGAAGAGACAGACAAGTATCCATAAAGAGGACAAAGCTAGGATCAAAGTGCTACTGCATTACTTCTTGCCTGATCTCTTCTTTGCTCCACGAGGTGAACTGAGTGATGATGAAGACTCTGTAAAGGAGCTCAACGGTCTAGGTAAAAATAACTAA

Transcript

amic_s0001.g101.t2

TATAAGCAGACGAAAGTACGGGAAGGGTTATCGTCGTTATTTGTGCATAATCCTGAAAATTGCTCACCATCCTTTTGTGGAGGAGTGGAATTGTTATCTTTTGGGTCTGAAGACTTTTTGACGGTAAGTTTGACATCCTTATTTTGGCGATGCACTCATTTGTCGTTCGATGAATCTGTTACTCGAGTATCTGTTATTATATCTGTGCACGGCAGTTCGTGTATGTTAAGAGACTGTAAGTCAATTTTTATAGTTTTTACTTAGCGATAAATGAAAGGAGACGTTATGTCTTTAATCAATGTTCCAAGTGAATTACATATCTTCAAGGAAAAGGCTATAAACAACCGTTTTTACGAGTGGAACGTGTGAAACTGTGCTGTATATTTATTACATGGAGAGTTTGTCACACACAATAGCCAAGGGCTAGAGTCACAACAGATGGTTTGAATGAGGGCTTGCAGCAAGACATGAAGAGGGTCCGTCCTGAAGACCATGACAGTGTCTATGGGCAGAACAGACAGGGTTTCCGCCCTCCCCCGGTTCTTGCACCAAACCCTGTTGGTATGGCAACTAATTATGATCAGCCCCTGCAGGATGGATTGAGTGGGTTGTCACAGTTTCCTGCTGCCGCACAAATGGCAGGGGCTCCAGGGTTTCAAGTGCAATCGCAAAATCCACAGTCCCATCCTCATGTACAGAATGCATCTTCAACACATCACCAAggtcaaactcaggttcatgcacaagcacaggctcagggacagCAACAACAGTTTCAAAGACTGAAGGTTGAGGATGCTCTGTCATACTTGGACCAAGTCAAGCTCCAGTTTGGCAACCAGCCTCAAGTTTACAATGATTTCTTGGATATCATGAAAGAGTTTAAGTCACAAAGTATTGACACTCCTGGAGTTATCAGCAGAGTTTCATCACTGTTCAAAGGTCACCCAGAACTCATTGTAGGCTTCAACACCTTCCTCCCTCCTGGGTACAAGATTGAGGTTCATGCTAGTGACCCAGGAACAGTCTCAGTTACAGCTCCTAATGGACAATCACAGATTACAACCATCCTTCAGCCAAATCAAAATCAACATCCACTTCATCAGTCTAGTGGCcaacagggacagcaacagcaacaagctcagcaaaaacaacagcagcagcaacagcaacaacaacagcagcctctgcagtcaccaacagcccagcaaGGACAGGGTCAACAGCCTGTGGAGTTTAACCATGCCATTAATTATGTCAACAAGATAAAGAATCGATTCCAAGGACAACCTGACATTTATAAGGCTTTCTTGGAAATCCTTCATACATATCAAAAGGAGCAGAAAATCATTAAGGAGGCTGCTATGCAAGGAACTCCACTTTCTGAGCAAGAGATTTACTTGAGAGAAGCTAAACTTGCTAATGAGGTTTACAAACAAGTTGCCAGGCTGTTTGAAAATCAAGAAGATTTGTTGCAAGAGTTCAGTCAGTTCCTTCCTGATGCAAATGGTGCTGCAACAATGCCTGGGGGTTTATTGTCCTCAAGTAAACTGCAGTCTCACCTAACTTCAGCAAGAAATGAATATGCACCTCCTGCGAAAAAACCTGCAGTGGGTCTGAATTCATCAAAACGCATCACACACCAGATAAGAAGAAATTCCAACAGTGTTTCATCATCACCTACACATTCCCAAACGAAGAAGAAATCAAGAAGTGCAATCAAAGATGTCTCCTTCGCAGAAGCACAACAAATTGGAACCTTGTCAGAATTTTCGTTCTTTGAAAAGGTGAAAAAAGCTCTAAAAAATAATGAGCTTTATAATAATTTTCTTCGCTGTCTTGTACTCTTCAATCAAGAAGTGATATCCAGATCAGAACTTGTGCAATTGGCTGCAAACTTCCTTGGTAAATACGCAGAGCTGTTCCAATGGTTCAAGGAATTCCTTGGTTATAAGGATTCATCTCCAATGGAAAGTGTGGCAAGTTTCAAAGAAAGAACGTCAGGAGAACTTCACCACCTTGAAATTGATTATTCTTCTTGTAAGAGGTATGGCACAAGTTACAGAGCCCTTCCCAAAAGCTACACACAGCCCAAGTGCAGTGGCCGTACAGCCCTGTGTAGAGAAGTCCTCAATGACACCTGGGTGTCCTTCCCATCTTGGTCAGAAGACACACCCTTTCCAGGAACAAGGAAAACACAATATGAAGAGTACATATTCAGGTGTGAGGATGAAAGGTTTGAGTTGGATGTTGTGTTGGAATCAAATCTCTCCACTATTCGGGTATTAGAAGCCATCCAGAAAAAGCTTCAGAGAATGCCAGCTGAAGAACAAGCTAAATTTCGACTCGACAGCTGTATAGGAGGAACCTCAGAATTCATCCACAGGAAAGCTATTCAGAGGATTTATGGAGACAAGGCTCCTGATATAGTTGACGGTTTGAAAAAAACACCTGCAGTTGCTGTCCCACTTGTATTAAAAAGATTAAAGACCAAAGAAGAGGAATGGCGTGAGTCTCAAAGACAATTTAACAAAATATGGAGAGATCAAAATGAAAAATATTATCTGAAGTCTTTGGATCATCAAGGCATTACATTTAAACAAAACGACTTGAAATCCATGAGGTCAAAAAGCCTTATTAATGAAATAGAGACAATTTATGATGAGAGACAAGAGCAAGCTGCAGAAGGTAATGGGGATGCAGCTGGTCCCCACTTAACCTTCAGCTATCAGGACAAGTCCATTCTAGATGACGCTGCTGGGCTCATTGTTCATCACATGAAGAGACAGACAAGTATCCATAAAGAGGACAAAGCTAGGATCAAAGTGCTACTGCATTACTTCTTGCCTGATCTCTTCTTTGCTCCACGAGGTGAACTGAGTGATGATGAAGACTCTGTAAAGGAGCTCAACGGTCTAGGTAAAAATAACTAAACAATGTACTGTGTTTCTTCTCTATTTTTACAATCTCCTTGGCTGAAAGGGAGGTTTATTTGTAGTTTAGTCAGTTTTTTNNNNNNNNNNNNNNNNNNNN

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q60520	Paired amphipathic helix protein Sin3a OS=Mus musculus OX=10090 GN=Sin3a PE=1 SV=3
Q96ST3	Paired amphipathic helix protein Sin3a OS=Homo sapiens OX=9606 GN=SIN3A PE=1 SV=2
Q62141	Paired amphipathic helix protein Sin3b OS=Mus musculus OX=10090 GN=Sin3b PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0002860 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF02671 all species →	PAH	Paired amphipathic helix repeat	Repeat	Interproscan
PF08295 all species →	Sin3_corepress	Sin3 family co-repressor	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR036600 all species →	Homologous_superfamily	Paired amphipathic helix superfamily	Interproscan
IPR003822 all species →	Repeat	Paired amphipathic helix	Interproscan
IPR013194 all species →	Domain	Histone deacetylase interacting domain	Interproscan
IPR039774 all species →	Family	Transcriptional regulatory protein Sin3-like	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR12346 all species →	SIN3B-RELATED	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0006355 all species →	Biological Process	regulation of DNA-templated transcription	Interproscan
GO:0000118 all species →	Cellular Component	histone deacetylase complex	Interproscan
GO:0000122 all species →	Biological Process	negative regulation of transcription by RNA polymerase II	Interproscan
GO:0000785 all species →	Cellular Component	chromatin	Interproscan
GO:0003714 all species →	Molecular Function	transcription corepressor activity	Interproscan
GO:0016580 all species →	Cellular Component	obsolete Sin3 complex	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K11644	SIN3A; paired amphipathic helix protein Sin3a	-	Chromosome and associated proteins	ko03036	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Acropora microphthalma tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Acropora microphthalma, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →